Zinc, copper and iron concentrations in cerebral cortex of male rats exposed to formaldehyde inhalation

Retrospective cohort studies and clinical findings have suggested effects of formaldehyde exposure on the central nervous system in anatomists, embalmers and pathologists. On the other hand, harmful effects of formaldehyde inhalation on the nervous system are not well documented. The concentrations of elements such as zinc, copper and iron within the cerebral cortex indicate whether physiological conditions are maintained. In this study, adult male albino Wistar rats were exposed to formaldehyde at different concentrations (0; 6.1; 12.2 mg·m-3) and during different periods of time (subacute-subchronic), and body weights were recorded weekly. Zinc, copper and iron concentrations were measured in the parietal cortex using atomic absorption spectrometry after wet ashing. We conclude that subacute or subchronic exposure to formaldehyde may cause growth retardation and alter zinc, copper and iron levels in the cerebral cortex.

Yazar Özen O.A.
Songur A.
Sarsilmaz M.
Yaman M.
Kuş I.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/8561
Tek Biçim Adres 10.1016/S0946-672X(03)80027-5
Konu Başlıkları Cerebral cortex
Copper
Formaldehyde exposure
Inhalation
Iron
Zinc
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Journal of Trace Elements in Medicine and Biology
Dergi Cilt Bilgisi 17
Dergi Sayısı 3
Sayfalar 207 - 209
Yayın Yılı 2003
Eser Adı
[dc.title]
Zinc, copper and iron concentrations in cerebral cortex of male rats exposed to formaldehyde inhalation
Yazar
[dc.contributor.author]
Özen O.A.
Yazar
[dc.contributor.author]
Songur A.
Yazar
[dc.contributor.author]
Sarsilmaz M.
Yazar
[dc.contributor.author]
Yaman M.
Yazar
[dc.contributor.author]
Kuş I.
Yayın Yılı
[dc.date.issued]
2003
Yayıncı
[dc.publisher]
Elsevier GmbH
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Retrospective cohort studies and clinical findings have suggested effects of formaldehyde exposure on the central nervous system in anatomists, embalmers and pathologists. On the other hand, harmful effects of formaldehyde inhalation on the nervous system are not well documented. The concentrations of elements such as zinc, copper and iron within the cerebral cortex indicate whether physiological conditions are maintained. In this study, adult male albino Wistar rats were exposed to formaldehyde at different concentrations (0; 6.1; 12.2 mg·m-3) and during different periods of time (subacute-subchronic), and body weights were recorded weekly. Zinc, copper and iron concentrations were measured in the parietal cortex using atomic absorption spectrometry after wet ashing. We conclude that subacute or subchronic exposure to formaldehyde may cause growth retardation and alter zinc, copper and iron levels in the cerebral cortex.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Cerebral cortex
Konu Başlıkları
[dc.subject]
Copper
Konu Başlıkları
[dc.subject]
Formaldehyde exposure
Konu Başlıkları
[dc.subject]
Inhalation
Konu Başlıkları
[dc.subject]
Iron
Konu Başlıkları
[dc.subject]
Zinc
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0946672X
İlk Sayfa Sayısı
[dc.identifier.startpage]
207
Son Sayfa Sayısı
[dc.identifier.endpage]
209
Dergi Adı
[dc.relation.journal]
Journal of Trace Elements in Medicine and Biology
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
17
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/S0946-672X(03)80027-5
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/8561
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
15
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 23:28
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Tıklayınız
formaldehyde copper concentrations cortex cerebral different system exposure effects nervous weekly recorded weights (subacute-subchronic) periods during mg·m-3) Retrospective measured subacute levels retardation growth subchronic parietal conclude ashing absorption atomic spectrometry pathologists inhalation harmful embalmers documented
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