Poly(3-hydroxyalkanoate)s: Diversification and biomedical applications: A state of the art review

Biomaterials have played an important role in the treatment of disease and the improvement of health care. Synthetic and naturally occurring biodegradable and biocompatible polymers have been used as biomaterials. Polyhydroxyalkanoates (PHAs) are promising materials for biomedical applications because they are biodegradable, non-toxic and biocompatible. We will shortly summarize the modification reactions, which include functionalization and grafting reactions, to improve the mechanical, thermal and hydrophilic properties of PHAs. The use of the modified PHAs in numerous biomedical applications, such as sutures, cardiovascular patches, wound dressings, scaffolds in tissue engineering, tissue repair/regeneration devices, drug carriers will be discussed in this review. © 2012 Elsevier B.V. All rights reserved.

Eser Adı
[dc.title]
Poly(3-hydroxyalkanoate)s: Diversification and biomedical applications: A state of the art review
Yayın Yılı
[dc.date.issued]
2012
Yayın Türü
[dc.type]
review
Özet
[dc.description.abstract]
Biomaterials have played an important role in the treatment of disease and the improvement of health care. Synthetic and naturally occurring biodegradable and biocompatible polymers have been used as biomaterials. Polyhydroxyalkanoates (PHAs) are promising materials for biomedical applications because they are biodegradable, non-toxic and biocompatible. We will shortly summarize the modification reactions, which include functionalization and grafting reactions, to improve the mechanical, thermal and hydrophilic properties of PHAs. The use of the modified PHAs in numerous biomedical applications, such as sutures, cardiovascular patches, wound dressings, scaffolds in tissue engineering, tissue repair/regeneration devices, drug carriers will be discussed in this review. © 2012 Elsevier B.V. All rights reserved.
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.msec.2012.01.021
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7051
Yayın Dili
[dc.language.iso]
eng
Yazar
[dc.contributor.author]
Hazer, Derya Burcu
Yazar
[dc.contributor.author]
Kılıçay, Ebru
Yazar
[dc.contributor.author]
Hazer, Baki
Künye
[dc.identifier.citation]
Hazer, D. B., Kılıçay, E. ve Hazer, B. (2012). Poly(3-hydroxyalkanoate)s: Diversification and biomedical applications: A state of the art review. Materials Science and Engineering: C, 32(4), 637-647. doi:10.1016/j.msec.2012.01.021
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
İlk Sayfa Sayısı
[dc.identifier.startpage]
637
Son Sayfa Sayısı
[dc.identifier.endpage]
647
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
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31
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1
09.12.2022 tarihinden bu yana
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09 Şubat 2024 06:27
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reactions applications biomedical tissue biocompatible biodegradable hydrophilic properties reserved rights modified numerous sutures cardiovascular patches discussed dressings scaffolds Elsevier engineering repair/regeneration mechanical devices carriers review thermal Biomaterials improve health polymers occurring naturally Synthetic improvement biomaterials
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