Effect of 2-octyl-cyanoacrylate on ischemic anastomosis of the left colon.

Introduction: 2-octyl-cyanoacrylate may be a good alternative in ischemic colon anastomosis without impairment of tissue perfusion. Methods: Forty male Wistar albino rats were randomized into four experimental groups (n = 10 in each group). In group 1 (control), a well-perfused left colonic segment was transected, and free ends were anastomosed by propylene sutures. In groups 2, 3, and 4, the animals underwent a standardized surgical procedure to induce ischemic left colon anastomosis. In group 2, an end-to-end anastomosis was created using six interrupted 6-0 polypropylene sutures between ischemic edges. In group 3, after approximating the mesenteric and antimesenteric edges of the anastomosis with two 6-0 polypropylene sutures, 2-octyl-cyanoacrylate was applied between the edges. In group 4, anastomosis was created by the same technique as described in group 2, and additionally 2-octyl-cyanoacrylate was applied on suture line. Rats were killed on day 4 following operation. Anastomotic integrity, intraperitoneal adhesion scores, anastomotic bursting pressures, and tissue hydroxyproline levels were recorded. Histopathological examination of the anastomosis was also performed. Results: There were no statistically significant differences among groups with respect to anastomotic integrity (p =.142). The mean bursting pressure values were 81.1 23.83, 43.3 26.06, 15.8 11.3, and 17.6 18.02 in groups 1, 2, 3, and 4, respectively. There were no statistically significant differences among groups 2, 3, and 4 with respect to tissue hydroxyproline levels and bursting pressure levels. The highest adhesion scores were observed in groups 3 and 4. Discussion: 2-octyl cyanoacrylate does not have additional advantages in the healing of experimental ischemic colon anastomosis.

Dergi Adı JOURNAL OF INVESTIGATIVE SURGERY
Dergi Cilt Bilgisi 22
Dergi Sayısı 3
Sayfalar 188 - 194
Yayın Yılı 2009
Eser Adı
[dc.title]
Effect of 2-octyl-cyanoacrylate on ischemic anastomosis of the left colon.
Yazar
[dc.contributor.author]
İrkörücü, Oktay
Yazar
[dc.contributor.author]
Uçan, Bülent Hamdi
Yazar
[dc.contributor.author]
Çakmak, Güldeniz Karadeniz
Yazar
[dc.contributor.author]
Taşçılar, Öğe
Yazar
[dc.contributor.author]
Emre, Ali Uğur
Yazar
[dc.contributor.author]
Ofluoğlu, Ebru
Yazar
[dc.contributor.author]
Bahadır, Burak
Yazar
[dc.contributor.author]
Karakaya, Kemal
Yazar
[dc.contributor.author]
Demirtaş, Canan
Yazar
[dc.contributor.author]
Paşaoğlu, Hatice
Yazar
[dc.contributor.author]
Ankaralı, Handan
Yazar
[dc.contributor.author]
Cömert, Mustafa
Yayın Yılı
[dc.date.issued]
2009
Yayıncı
[dc.publisher]
TAYLOR & FRANCIS INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Introduction: 2-octyl-cyanoacrylate may be a good alternative in ischemic colon anastomosis without impairment of tissue perfusion. Methods: Forty male Wistar albino rats were randomized into four experimental groups (n = 10 in each group). In group 1 (control), a well-perfused left colonic segment was transected, and free ends were anastomosed by propylene sutures. In groups 2, 3, and 4, the animals underwent a standardized surgical procedure to induce ischemic left colon anastomosis. In group 2, an end-to-end anastomosis was created using six interrupted 6-0 polypropylene sutures between ischemic edges. In group 3, after approximating the mesenteric and antimesenteric edges of the anastomosis with two 6-0 polypropylene sutures, 2-octyl-cyanoacrylate was applied between the edges. In group 4, anastomosis was created by the same technique as described in group 2, and additionally 2-octyl-cyanoacrylate was applied on suture line. Rats were killed on day 4 following operation. Anastomotic integrity, intraperitoneal adhesion scores, anastomotic bursting pressures, and tissue hydroxyproline levels were recorded. Histopathological examination of the anastomosis was also performed. Results: There were no statistically significant differences among groups with respect to anastomotic integrity (p =.142). The mean bursting pressure values were 81.1 23.83, 43.3 26.06, 15.8 11.3, and 17.6 18.02 in groups 1, 2, 3, and 4, respectively. There were no statistically significant differences among groups 2, 3, and 4 with respect to tissue hydroxyproline levels and bursting pressure levels. The highest adhesion scores were observed in groups 3 and 4. Discussion: 2-octyl cyanoacrylate does not have additional advantages in the healing of experimental ischemic colon anastomosis.
Açıklama
[dc.description]
WOS: 000266280200006
Açıklama
[dc.description]
PubMed: 19466656
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Cyanoacrylate
Konu Başlıkları
[dc.subject]
Anastomosis
Konu Başlıkları
[dc.subject]
Ischemia
Konu Başlıkları
[dc.subject]
Colon
Konu Başlıkları
[dc.subject]
Complication
Künye
[dc.identifier.citation]
Irkorucu, O., Ucan, B. H., Cakmak, G. K., Tascilar, O., Emre, A. U., Ofluoglu, E., … Comert, M. (2009). Effect of 2-octyl-cyanoacrylate on ischemic anastomosis of the left colon. Journal of Investigative Surgery, 22(3), 188-194. doi:10.1080/08941930902866261
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0894-1939
ISSN
[dc.identifier.issn]
1521-0553
İlk Sayfa Sayısı
[dc.identifier.startpage]
188
Son Sayfa Sayısı
[dc.identifier.endpage]
194
Dergi Adı
[dc.relation.journal]
JOURNAL OF INVESTIGATIVE SURGERY
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
22
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1080/08941930902866261
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2435
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
125
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
17 Nisan 2024 13:24
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Tıklayınız
anastomosis groups ischemic 2-octyl-cyanoacrylate tissue bursting levels sutures created statistically pressure polypropylene between differences experimental significant applied hydroxyproline anastomotic scores adhesion respect integrity Introduction Results performed examination Histopathological recorded pressures intraperitoneal values healing advantages additional
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