Urinary albumin excretion among nondipper hypertensive patients is closely related with the pattern of nondipping

The relationship between 24-hour urinary albumin excretion (UAE) rate and the pattern of nondipping (isolated systolic nondipping, isolated diastolic nondipping, and both systolic and diastolic nondipping) is not known. Medical history, physical examination, laboratory analysis, and office and ambulatory blood pressure measurements were performed. Twenty-four hour urine specimens were collected to determine creatinine clearance and UAE. In total, 158 essential hypertensive patients (104 dippers, 54 nondippers) were included. Fourteen patients were isolated systolic nondippers, 7 patients were isolated diastolic nondippers, and 33 patients were both systolic and diastolic nondippers. Among nondipper patients, 17 had microalbuminuria and, among dipper patients, 9 had microalbuminuria (P < .0001). The median UAE of dippers was lower when compared with nondippers (5.25 mg/day vs.23 mg/day, P < .0001). The median UAE of isolated systolic nondippers, isolated diastolic nondippers, and both systolic and diastolic nondippers were 8.45 mg/day, 7.7 mg/day, and 25.5 mg/day, respectively (P = .001). Subgroup comparison of patients revealed that UAE was higher in patients with both systolic and diastolic nondippers when compared with dippers (P < .0001), isolated systolic nondippers (P = .001), and isolated diastolic nondippers (P = .017). Not only nondipping itself, but nondipping profile may be related with UAE in essential hypertensive patients. J Am Soc Hypertens 2010;4(4):196-202. (C) 2010 American Society of Hypertension. All rights reserved.

Dergi Adı JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
Dergi Cilt Bilgisi 4
Dergi Sayısı 4
Sayfalar 196 - 202
Yayın Yılı 2010
Eser Adı
[dc.title]
Urinary albumin excretion among nondipper hypertensive patients is closely related with the pattern of nondipping
Yazar
[dc.contributor.author]
Afsar, Baris
Yazar
[dc.contributor.author]
Elsurer, Rengin
Yayın Yılı
[dc.date.issued]
2010
Yayıncı
[dc.publisher]
ELSEVIER SCIENCE INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The relationship between 24-hour urinary albumin excretion (UAE) rate and the pattern of nondipping (isolated systolic nondipping, isolated diastolic nondipping, and both systolic and diastolic nondipping) is not known. Medical history, physical examination, laboratory analysis, and office and ambulatory blood pressure measurements were performed. Twenty-four hour urine specimens were collected to determine creatinine clearance and UAE. In total, 158 essential hypertensive patients (104 dippers, 54 nondippers) were included. Fourteen patients were isolated systolic nondippers, 7 patients were isolated diastolic nondippers, and 33 patients were both systolic and diastolic nondippers. Among nondipper patients, 17 had microalbuminuria and, among dipper patients, 9 had microalbuminuria (P < .0001). The median UAE of dippers was lower when compared with nondippers (5.25 mg/day vs.23 mg/day, P < .0001). The median UAE of isolated systolic nondippers, isolated diastolic nondippers, and both systolic and diastolic nondippers were 8.45 mg/day, 7.7 mg/day, and 25.5 mg/day, respectively (P = .001). Subgroup comparison of patients revealed that UAE was higher in patients with both systolic and diastolic nondippers when compared with dippers (P < .0001), isolated systolic nondippers (P = .001), and isolated diastolic nondippers (P = .017). Not only nondipping itself, but nondipping profile may be related with UAE in essential hypertensive patients. J Am Soc Hypertens 2010;4(4):196-202. (C) 2010 American Society of Hypertension. All rights reserved.
Açıklama
[dc.description]
WOS: 000281294600007
Açıklama
[dc.description]
PubMed: 20655503
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Essential hypertension
Konu Başlıkları
[dc.subject]
dipper
Konu Başlıkları
[dc.subject]
nondipper
Konu Başlıkları
[dc.subject]
urinary albumin excretion
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1933-1711
İlk Sayfa Sayısı
[dc.identifier.startpage]
196
Son Sayfa Sayısı
[dc.identifier.endpage]
202
Dergi Adı
[dc.relation.journal]
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
4
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.jash.2010.06.004
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3747
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
22
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
06 Şubat 2024 17:08
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nondippers patients systolic diastolic isolated mg/day nondipping dippers essential hypertensive median microalbuminuria compared comparison Subgroup urinary between respectively revealed 24-hour Hypertens reserved rights Hypertension Society American 196-202 related profile itself higher excretion albumin pressure collected
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