Dobrava hantavirus variants found in Apodemus flavicollis mice in Krklareli Province, Turkey

Hantaviruses infect humans via inhalation of viral particles within secretions of infected rodents or rarely through direct contact with infected rodents. Determining the prevalence of hantavirus infections among rodent populations is of vital importance to obtain information on hantavirus-related cases and to predict possible outbreaks. We hypothesized that DOBV strains circulating in the Thrace Region in Turkey would be related to other Balkan DOBV strains. In this study, hantavirus infections in the rodent population of the Krklareli-neada Region (north-western Turkey, near the Bulgarian border) were investigated. This region is of particular importance, as it is located in the south-eastern margin of the European continent and was used as an entrance point of Asian faunal elements into Europe. DOBV infection was detected in eight of 73 rodents; all were of the Apodemus flavicollis species. Partial sequences of the viral S-, M-, and L-genome segments were recovered and compared with previously reported DOBV sequences. The newly characterized Turkish strains were similar to other DOBV variants. Silent nucleotide mutations were dominant. The hantavirus prevalence in the neada region was similar to what has been reported in Greece and Bulgaria. For the first time, the M-segment sequences of DOBV from Turkey were recovered and genetic data of hantaviruses from Thrace region of Turkey were obtained.

Yazar Polat, Ceylan
Sironen, Tarja
Plyusnina, Angelina
Karatas, Ahmet
Sozen, Mustafa
Matur, Ferhat
Vapalahti, Olli
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2411
Tek Biçim Adres 10.1002/jmv.25036
Konu Başlıkları DOBV
Hantavirus
phylogenetic analysis
rodent
Turkey
Zoonosis
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı JOURNAL OF MEDICAL VIROLOGY
Dergi Cilt Bilgisi 90
Dergi Sayısı 5
Sayfalar 810 - 818
Yayın Yılı 2018
Eser Adı
[dc.title]
Dobrava hantavirus variants found in Apodemus flavicollis mice in Krklareli Province, Turkey
Yazar
[dc.contributor.author]
Polat, Ceylan
Yazar
[dc.contributor.author]
Sironen, Tarja
Yazar
[dc.contributor.author]
Plyusnina, Angelina
Yazar
[dc.contributor.author]
Karatas, Ahmet
Yazar
[dc.contributor.author]
Sozen, Mustafa
Yazar
[dc.contributor.author]
Matur, Ferhat
Yazar
[dc.contributor.author]
Vapalahti, Olli
Yayın Yılı
[dc.date.issued]
2018
Yayıncı
[dc.publisher]
WILEY
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Hantaviruses infect humans via inhalation of viral particles within secretions of infected rodents or rarely through direct contact with infected rodents. Determining the prevalence of hantavirus infections among rodent populations is of vital importance to obtain information on hantavirus-related cases and to predict possible outbreaks. We hypothesized that DOBV strains circulating in the Thrace Region in Turkey would be related to other Balkan DOBV strains. In this study, hantavirus infections in the rodent population of the Krklareli-neada Region (north-western Turkey, near the Bulgarian border) were investigated. This region is of particular importance, as it is located in the south-eastern margin of the European continent and was used as an entrance point of Asian faunal elements into Europe. DOBV infection was detected in eight of 73 rodents; all were of the Apodemus flavicollis species. Partial sequences of the viral S-, M-, and L-genome segments were recovered and compared with previously reported DOBV sequences. The newly characterized Turkish strains were similar to other DOBV variants. Silent nucleotide mutations were dominant. The hantavirus prevalence in the neada region was similar to what has been reported in Greece and Bulgaria. For the first time, the M-segment sequences of DOBV from Turkey were recovered and genetic data of hantaviruses from Thrace region of Turkey were obtained.
Açıklama
[dc.description]
WOS: 000427254600005
Açıklama
[dc.description]
PubMed: 29377182
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
DOBV
Konu Başlıkları
[dc.subject]
Hantavirus
Konu Başlıkları
[dc.subject]
phylogenetic analysis
Konu Başlıkları
[dc.subject]
rodent
Konu Başlıkları
[dc.subject]
Turkey
Konu Başlıkları
[dc.subject]
Zoonosis
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0146-6615
ISSN
[dc.identifier.issn]
1096-9071
Sponsor YAYINCI
[dc.description.sponsorship]
Federation of European Microbiological Societies FEMS Research Fellowship
Sponsor YAYINCI
[dc.description.sponsorship]
Federation of European Microbiological Societies FEMS Research Fellowship
İlk Sayfa Sayısı
[dc.identifier.startpage]
810
Son Sayfa Sayısı
[dc.identifier.endpage]
818
Dergi Adı
[dc.relation.journal]
JOURNAL OF MEDICAL VIROLOGY
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
90
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1002/jmv.25036
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2411
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
14
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 12:23
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Tıklayınız
Turkey region strains rodents hantavirus sequences importance similar reported Thrace Region recovered rodent infections prevalence infected L-genome faunal elements Europe infection detected Partial species flavicollis Apodemus segments Hantaviruses compared obtained hantaviruses genetic M-segment Bulgaria Greece
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