Unpredicted effects of Ankaferd (R) on cartilage tissue

Objective: This study aims to investigate the histopathological changes secondary to the administration of Ankaferd Blood Stopper (R) (ABS) into the auricular cartilage. Materials and methods: Both of the auricular cartilages of thirty New Zealand rabbits were marked with tattoo ink. A 0.2-cc ABS (study group, n: 30) and 0.2 cc physiological saline (control group, n: 30) were subcutaneously infused into the right auricle and left auricle, respectively. All layers were removed at 14 days. Results: The ABS group had significantly higher level of fibrosis, necrosis, foreign body reaction, inflammation, and cartilage degeneration, compared to the controls. Conclusion: Our study results showed that ABS administration into a closed cavity led to a significantly increased fibrosis and necrosis in the auricular cartilage.

Yazar Evren, Cenk
Ugur, Mehmet Birol
Yildirim, Burhan
Bektas, Sibel
Yigit, Volkan Bilge
Cinar, Fikret
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3745
Konu Başlıkları Ankaferd
hemostatic agent
cartilage
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
Dergi Cilt Bilgisi 8
Dergi Sayısı 1
Sayfalar 922 -
Yayın Yılı 2015
Eser Adı
[dc.title]
Unpredicted effects of Ankaferd (R) on cartilage tissue
Yazar
[dc.contributor.author]
Evren, Cenk
Yazar
[dc.contributor.author]
Ugur, Mehmet Birol
Yazar
[dc.contributor.author]
Yildirim, Burhan
Yazar
[dc.contributor.author]
Bektas, Sibel
Yazar
[dc.contributor.author]
Yigit, Volkan Bilge
Yazar
[dc.contributor.author]
Cinar, Fikret
Yayın Yılı
[dc.date.issued]
2015
Yayıncı
[dc.publisher]
E-CENTURY PUBLISHING CORP
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective: This study aims to investigate the histopathological changes secondary to the administration of Ankaferd Blood Stopper (R) (ABS) into the auricular cartilage. Materials and methods: Both of the auricular cartilages of thirty New Zealand rabbits were marked with tattoo ink. A 0.2-cc ABS (study group, n: 30) and 0.2 cc physiological saline (control group, n: 30) were subcutaneously infused into the right auricle and left auricle, respectively. All layers were removed at 14 days. Results: The ABS group had significantly higher level of fibrosis, necrosis, foreign body reaction, inflammation, and cartilage degeneration, compared to the controls. Conclusion: Our study results showed that ABS administration into a closed cavity led to a significantly increased fibrosis and necrosis in the auricular cartilage.
Açıklama
[dc.description]
WOS: 000349897200109
Açıklama
[dc.description]
PubMed: 25785076
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Ankaferd
Konu Başlıkları
[dc.subject]
hemostatic agent
Konu Başlıkları
[dc.subject]
cartilage
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1940-5901
İlk Sayfa Sayısı
[dc.identifier.startpage]
922
Dergi Adı
[dc.relation.journal]
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
8
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3745
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
9
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 21:50
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Tıklayınız
cartilage auricular fibrosis necrosis significantly auricle administration higher Results removed layers Objective inflammation showed increased cavity closed results foreign Conclusion controls compared degeneration reaction respectively methods Materials Stopper Ankaferd thirty secondary changes histopathological investigate cartilages
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