Pretreatment Neutrophil- Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy

Objective. To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low-from high-grade parotid gland tumors. Study Design. Case series with chart review. Setting. Tertiary referral center. Subjects and Methods. This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Results. Mean neutrophil percentage (63.50% +/- 12.11% vs 58.76% +/- 8.20%, P =.008) and NLR (3.29+/-3.13 vs 2.13 +/- 1.26, P =.008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42+/-0.72 10(3)/mm(3) vs 1.97+/-0.87 10(3)/mm(3) , P<.001) and percentage (30.67%+/-7.68% vs 26.86%+/-10.15%, P =.011) were lower in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte percentage and NLR were significantly different between low-and high-grade malignant parotid gland tumors (P =.026 and P =.030, respectively). Conclusion. Elevated NLR could be an inflammatory marker to distinguish low-from high-grade malignant parotid gland tumors.

Yazar Damar, Murat
Dinc, Aykut Erdem
Erdem, Duygu
Aydil, Utku
Kizil, Yusuf
Eravci, Fakih Cihat
Biskin, Sultan
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3142
Tek Biçim Adres 10.1177/0194599816659257
Konu Başlıkları salivary gland tumors
neutrophil-lymphocyte ratio
inflammatory marker
high-grade malignant tumor
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı OTOLARYNGOLOGY-HEAD AND NECK SURGERY
Dergi Cilt Bilgisi 155
Dergi Sayısı 6
Sayfalar 988 - 996
Yayın Yılı 2016
Eser Adı
[dc.title]
Pretreatment Neutrophil- Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy
Yazar
[dc.contributor.author]
Damar, Murat
Yazar
[dc.contributor.author]
Dinc, Aykut Erdem
Yazar
[dc.contributor.author]
Erdem, Duygu
Yazar
[dc.contributor.author]
Aydil, Utku
Yazar
[dc.contributor.author]
Kizil, Yusuf
Yazar
[dc.contributor.author]
Eravci, Fakih Cihat
Yazar
[dc.contributor.author]
Biskin, Sultan
Yayın Yılı
[dc.date.issued]
2016
Yayıncı
[dc.publisher]
SAGE PUBLICATIONS LTD
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective. To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low-from high-grade parotid gland tumors. Study Design. Case series with chart review. Setting. Tertiary referral center. Subjects and Methods. This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Results. Mean neutrophil percentage (63.50% +/- 12.11% vs 58.76% +/- 8.20%, P =.008) and NLR (3.29+/-3.13 vs 2.13 +/- 1.26, P =.008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42+/-0.72 10(3)/mm(3) vs 1.97+/-0.87 10(3)/mm(3) , P<.001) and percentage (30.67%+/-7.68% vs 26.86%+/-10.15%, P =.011) were lower in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte percentage and NLR were significantly different between low-and high-grade malignant parotid gland tumors (P =.026 and P =.030, respectively). Conclusion. Elevated NLR could be an inflammatory marker to distinguish low-from high-grade malignant parotid gland tumors.
Açıklama
[dc.description]
WOS: 000389146500012
Açıklama
[dc.description]
PubMed: 27436419
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
salivary gland tumors
Konu Başlıkları
[dc.subject]
neutrophil-lymphocyte ratio
Konu Başlıkları
[dc.subject]
inflammatory marker
Konu Başlıkları
[dc.subject]
high-grade malignant tumor
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0194-5998
ISSN
[dc.identifier.issn]
1097-6817
İlk Sayfa Sayısı
[dc.identifier.startpage]
988
Son Sayfa Sayısı
[dc.identifier.endpage]
996
Dergi Adı
[dc.relation.journal]
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
155
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1177/0194599816659257
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3142
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
24
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 21:39
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Tıklayınız
malignant patients tumors benign percentage parotid high-grade leukocytes percentages 10(3)/mm(3) between low-from marker inflammatory lymphocyte counts significantly 29+/-3 distinguish higher Elevated low-and different respectively) Conclusion 86%+/-10 67%+/-7 97+/-0 42+/-0 Objective neutrophil Tertiary Setting review series
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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