Bone Pain Assessment and Relationship with Parathyroid Hormone and Health-Related Quality of Life in Hemodialysis

Renal osteodystrophy is a common problem in renal failure patients. Bone pain is a common manifestation of renal osteodystrophy. The aim of the study was to assess the intensity of chronic bone pain via visual analog scale (VAS) and its relationship with parathyroid hormone, health-related quality of life (HRQoL), and depression in hemodialysis patients. Ninety-five patients recruited were asked to rate chronic bone pain via VAS. Depressive symptoms and HRQoL were assessed by Beck Depression Inventory (BDI) and Short-Form 36, respectively. VAS was positively correlated with intact parathyroid hormone (r (_) +0.322, p (-) 0.001), phosphorus (r- +0.300, p -0.003), alkaline phosphatase (r- +0.275, p = 0.009), and negatively correlated with physical component (r= - 0.320, p 0.002) and mental component summary scores (r = -0.247, p = 0.016). In multivariate linear regression analysis, logVAS was independently associated with serum phosphorus (beta = 0.072, 95% confidence interval: 0.020-0.123, p = 0.007), log intact parathyroid hormone (beta = 0.176, 95% confidence interval: 0.041-0.310, p = 0.011), and physical component summary score (beta = -0.018, 95% confidence interval: -0.031-(-0.005), p - 0.008). VAS is correlated with bone metabolism markers, namely, intact parathyroid hormone, and may be used to assess the intensity of chronic bone pain. The intensity of chronic bone pain is related with HRQoL in hemodialysis patients.

Yazar Elsurer, Rengin
Afsar, Baris
Mercanoglu, Esra
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2170
Tek Biçim Adres 10.3109/0886022X.2013.780617
Konu Başlıkları depression
hemodialysis
pain
parathyroid hormone
renal osteodystrophy
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı RENAL FAILURE
Dergi Cilt Bilgisi 35
Dergi Sayısı 5
Sayfalar 667 - 672
Yayın Yılı 2013
Eser Adı
[dc.title]
Bone Pain Assessment and Relationship with Parathyroid Hormone and Health-Related Quality of Life in Hemodialysis
Yazar
[dc.contributor.author]
Elsurer, Rengin
Yazar
[dc.contributor.author]
Afsar, Baris
Yazar
[dc.contributor.author]
Mercanoglu, Esra
Yayın Yılı
[dc.date.issued]
2013
Yayıncı
[dc.publisher]
INFORMA HEALTHCARE
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Renal osteodystrophy is a common problem in renal failure patients. Bone pain is a common manifestation of renal osteodystrophy. The aim of the study was to assess the intensity of chronic bone pain via visual analog scale (VAS) and its relationship with parathyroid hormone, health-related quality of life (HRQoL), and depression in hemodialysis patients. Ninety-five patients recruited were asked to rate chronic bone pain via VAS. Depressive symptoms and HRQoL were assessed by Beck Depression Inventory (BDI) and Short-Form 36, respectively. VAS was positively correlated with intact parathyroid hormone (r (_) +0.322, p (-) 0.001), phosphorus (r- +0.300, p -0.003), alkaline phosphatase (r- +0.275, p = 0.009), and negatively correlated with physical component (r= - 0.320, p 0.002) and mental component summary scores (r = -0.247, p = 0.016). In multivariate linear regression analysis, logVAS was independently associated with serum phosphorus (beta = 0.072, 95% confidence interval: 0.020-0.123, p = 0.007), log intact parathyroid hormone (beta = 0.176, 95% confidence interval: 0.041-0.310, p = 0.011), and physical component summary score (beta = -0.018, 95% confidence interval: -0.031-(-0.005), p - 0.008). VAS is correlated with bone metabolism markers, namely, intact parathyroid hormone, and may be used to assess the intensity of chronic bone pain. The intensity of chronic bone pain is related with HRQoL in hemodialysis patients.
Açıklama
[dc.description]
WOS: 000318951100011
Açıklama
[dc.description]
PubMed: 23560898
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
depression
Konu Başlıkları
[dc.subject]
hemodialysis
Konu Başlıkları
[dc.subject]
pain
Konu Başlıkları
[dc.subject]
parathyroid hormone
Konu Başlıkları
[dc.subject]
renal osteodystrophy
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0886-022X
İlk Sayfa Sayısı
[dc.identifier.startpage]
667
Son Sayfa Sayısı
[dc.identifier.endpage]
672
Dergi Adı
[dc.relation.journal]
RENAL FAILURE
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
35
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.3109/0886022X.2013.780617
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2170
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
17
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
11 Nisan 2024 03:05
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Tıklayınız
patients hormone chronic parathyroid confidence correlated intact intensity component interval physical osteodystrophy phosphorus summary hemodialysis assess common markers namely related mental scores metabolism 031-(-0 multivariate associated independently logVAS analysis regression linear negatively Ninety-five depression (HRQoL)
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