Influence of smoking on serum an milk malondialdehyde, superoxide dismutase, glutathione peroxidase, and antioxidant potential levels in mothers at the postpartum seventh day

The aim of the study was to investigate simultaneously serum and milk malondialdehyde (MDA) levels, superoxide dismutase (SOD), glutathione peroxidase (GPx) activities, and antioxidant potential (AOP) in active-smoking, passive-smoking, and nonsmoking mothers and to search if there is any difference between serum and milk oxidant/ antioxidant status caused by smoking. According to their smoking status, 60 mothers (age range: 20-35 yr) were classified into one of three groups: the active-smoking mothers (n=15), the passive-smoking mothers (n=22), and the nonsmoking mothers (n=23). Serum and milk MDA, SOD, GPx, and AOP values were determined in mothers on the postpartum seventh day by the spectrophotometric method. Serum Zn and Cu concentrations were determined by atomic absorption spectrophotometry (AAS). There was no significant difference in serum samples with respect to MDA (p=0.17), SOD (p=0.51), and AOP (p=0.36) levels, but there was a significant difference in serum GPx (p=0.002) levels among the study groups. The significant differences were also found in milk samples in terms of MDA (p=0.002) and SOD (p=0.011), but not in GPx (p=0.11) and AOP (p=0.29) levels among the study groups. No significant difference was seen in serum zinc concentration (p=0.49), but copper concentration differed significantly among the groups (p=0.005). These observations suggest that human milk is more vulnerable to oxidative stress and lipid peroxidation than serum samples in smoking mothers, even if they are passive smokers.

Yazar Ermis, B
Yildirim, A
Ors, R
Tastekin, A
Ozkan, B
Akcay, F
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2783
Tek Biçim Adres 10.1385/BTER:105:1-3:027
Konu Başlıkları smoking
serum antioxidants
malondialdehyde
superoxide dismutase
glutathione peroxidase
human milk
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı BIOLOGICAL TRACE ELEMENT RESEARCH
Dergi Cilt Bilgisi 105
Dergi Sayısı 01.Mar
Sayfalar 27 - 36
Yayın Yılı 2005
Eser Adı
[dc.title]
Influence of smoking on serum an milk malondialdehyde, superoxide dismutase, glutathione peroxidase, and antioxidant potential levels in mothers at the postpartum seventh day
Yazar
[dc.contributor.author]
Ermis, B
Yazar
[dc.contributor.author]
Yildirim, A
Yazar
[dc.contributor.author]
Ors, R
Yazar
[dc.contributor.author]
Tastekin, A
Yazar
[dc.contributor.author]
Ozkan, B
Yazar
[dc.contributor.author]
Akcay, F
Yayın Yılı
[dc.date.issued]
2005
Yayıncı
[dc.publisher]
HUMANA PRESS INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The aim of the study was to investigate simultaneously serum and milk malondialdehyde (MDA) levels, superoxide dismutase (SOD), glutathione peroxidase (GPx) activities, and antioxidant potential (AOP) in active-smoking, passive-smoking, and nonsmoking mothers and to search if there is any difference between serum and milk oxidant/ antioxidant status caused by smoking. According to their smoking status, 60 mothers (age range: 20-35 yr) were classified into one of three groups: the active-smoking mothers (n=15), the passive-smoking mothers (n=22), and the nonsmoking mothers (n=23). Serum and milk MDA, SOD, GPx, and AOP values were determined in mothers on the postpartum seventh day by the spectrophotometric method. Serum Zn and Cu concentrations were determined by atomic absorption spectrophotometry (AAS). There was no significant difference in serum samples with respect to MDA (p=0.17), SOD (p=0.51), and AOP (p=0.36) levels, but there was a significant difference in serum GPx (p=0.002) levels among the study groups. The significant differences were also found in milk samples in terms of MDA (p=0.002) and SOD (p=0.011), but not in GPx (p=0.11) and AOP (p=0.29) levels among the study groups. No significant difference was seen in serum zinc concentration (p=0.49), but copper concentration differed significantly among the groups (p=0.005). These observations suggest that human milk is more vulnerable to oxidative stress and lipid peroxidation than serum samples in smoking mothers, even if they are passive smokers.
Açıklama
[dc.description]
WOS: 000230740800004
Açıklama
[dc.description]
PubMed: 16034151
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
smoking
Konu Başlıkları
[dc.subject]
serum antioxidants
Konu Başlıkları
[dc.subject]
malondialdehyde
Konu Başlıkları
[dc.subject]
superoxide dismutase
Konu Başlıkları
[dc.subject]
glutathione peroxidase
Konu Başlıkları
[dc.subject]
human milk
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0163-4984
İlk Sayfa Sayısı
[dc.identifier.startpage]
27
Son Sayfa Sayısı
[dc.identifier.endpage]
36
Dergi Adı
[dc.relation.journal]
BIOLOGICAL TRACE ELEMENT RESEARCH
Dergi Sayısı
[dc.identifier.issue]
01.Mar
Dergi Cilt Bilgisi
[dc.identifier.volume]
105
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1385/BTER:105:1-3:027
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2783
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
6
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 11:15
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mothers groups levels significant difference smoking samples determined concentration passive-smoking antioxidant active-smoking status nonsmoking peroxidation differences oxidative passive respect smokers stress vulnerable observations significantly differed copper suggest values activities According caused oxidant/ between search potential
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