Hygroma colli cysticum: Prenatal diagnosis and prognosis

The objective of this study is to analyze the prenatal management and prognostic factors of hygroma colli cysticum by using cytogenetic tests and sonographic morphological features. All cases with hygroma colli cysticum diagnosed and managed at our Prenatal Diagnostics Unit between January 96 and September 2000 were analyzed. Sonographic morphological features were divided in two groups; nonseptated (n = 18) and septated (n = 12) hygroma colli cysticum lesions were compared with fetal karyotype results and pregnancy outcome data. Statistical analysis was performed by Chi-square test and statistical significance was defined as p < 0.05. In 5 years, 30 cases with hygroma colli cysticum were identified. Cytogenetic results were obtained from 23 (76.7%) cases (four chorionic villus sampling and 19 amniocentesis). Chromosomal abnormalities were present in 13 cases (56.5%). The most common chromosomal abnormality was Turner Syndrome (four cases, 17.4%) and Trisomy 18 (four cases, 17.4%). Pregnancy outcome data were available for 29 patients. Those fetuses with septated hygroma colli cysticum tended to have a worse fetal outcome, without statistical significance (p > 0.05), compared with the nonseptated hygroma colli cysticum cases (75 vs. 61.1%, respectively). Fetal hygroma colli cysticum, either septated or not, carries high risks of aneuploidies and adverse fetal outcome. Recommended management includes karyotyping and if parents decide to continue the pregnancy ultrasound scan at 20 to 22 weeks' gestation is necessary, for excluding associated anomalies. At birth, if the cystic hygroma persists, it should be noted that a respiratory difficulty can happen and a pediatrician should standby as a precaution.

Yazar Tanriverdi, HA
Hendrik, HJ
Ertan, AK
Axt, R
Schmidt, W
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2736
Tek Biçim Adres 10.1055/s-2001-18786
Konu Başlıkları hygroma colli cysticum
prenatal diagnosis
karyotyping
ultrasound
prognosis
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı AMERICAN JOURNAL OF PERINATOLOGY
Dergi Cilt Bilgisi 18
Dergi Sayısı 8
Sayfalar 415 - 420
Yayın Yılı 2001
Eser Adı
[dc.title]
Hygroma colli cysticum: Prenatal diagnosis and prognosis
Yazar
[dc.contributor.author]
Tanriverdi, HA
Yazar
[dc.contributor.author]
Hendrik, HJ
Yazar
[dc.contributor.author]
Ertan, AK
Yazar
[dc.contributor.author]
Axt, R
Yazar
[dc.contributor.author]
Schmidt, W
Yayın Yılı
[dc.date.issued]
2001
Yayıncı
[dc.publisher]
THIEME MEDICAL PUBL INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The objective of this study is to analyze the prenatal management and prognostic factors of hygroma colli cysticum by using cytogenetic tests and sonographic morphological features. All cases with hygroma colli cysticum diagnosed and managed at our Prenatal Diagnostics Unit between January 96 and September 2000 were analyzed. Sonographic morphological features were divided in two groups; nonseptated (n = 18) and septated (n = 12) hygroma colli cysticum lesions were compared with fetal karyotype results and pregnancy outcome data. Statistical analysis was performed by Chi-square test and statistical significance was defined as p < 0.05. In 5 years, 30 cases with hygroma colli cysticum were identified. Cytogenetic results were obtained from 23 (76.7%) cases (four chorionic villus sampling and 19 amniocentesis). Chromosomal abnormalities were present in 13 cases (56.5%). The most common chromosomal abnormality was Turner Syndrome (four cases, 17.4%) and Trisomy 18 (four cases, 17.4%). Pregnancy outcome data were available for 29 patients. Those fetuses with septated hygroma colli cysticum tended to have a worse fetal outcome, without statistical significance (p > 0.05), compared with the nonseptated hygroma colli cysticum cases (75 vs. 61.1%, respectively). Fetal hygroma colli cysticum, either septated or not, carries high risks of aneuploidies and adverse fetal outcome. Recommended management includes karyotyping and if parents decide to continue the pregnancy ultrasound scan at 20 to 22 weeks' gestation is necessary, for excluding associated anomalies. At birth, if the cystic hygroma persists, it should be noted that a respiratory difficulty can happen and a pediatrician should standby as a precaution.
Açıklama
[dc.description]
WOS: 000172803700001
Açıklama
[dc.description]
PubMed: 11733855
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
hygroma colli cysticum
Konu Başlıkları
[dc.subject]
prenatal diagnosis
Konu Başlıkları
[dc.subject]
karyotyping
Konu Başlıkları
[dc.subject]
ultrasound
Konu Başlıkları
[dc.subject]
prognosis
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0735-1631
İlk Sayfa Sayısı
[dc.identifier.startpage]
415
Son Sayfa Sayısı
[dc.identifier.endpage]
420
Dergi Adı
[dc.relation.journal]
AMERICAN JOURNAL OF PERINATOLOGY
Dergi Sayısı
[dc.identifier.issue]
8
Dergi Cilt Bilgisi
[dc.identifier.volume]
18
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1055/s-2001-18786
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2736
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
17
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Nisan 2024 01:46
Google Kontrol
Tıklayınız
hygroma cysticum outcome septated statistical nonseptated compared significance results pregnancy should management morphological features respectively) either happen without pediatrician tended fetuses patients standby available Pregnancy Trisomy precaution carries associated excluding necessary gestation cystic ultrasound continue
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms