Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer in Untreated Patients with Obstructive Sleep Apnea-Hypopnea Syndrome: A Case-Control Study

Purpose: To evaluate peripapillary choroidal thickness (PPCT), central macular choroidal thickness (CMCT), and retinal nerve fiber layer (RNFL) thickness in untreated patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).Methods: This prospective, randomized, and comparative study was conducted in a university ophthalmology clinic. 106 eyes of 106 patients with OSAHS and 44 eyes of 44 healthy individuals were evaluated in this study. Only right eyes were evaluated. The patients with OSAHS were divided into three groups as mild (group 1), moderate (group 2), and severe (group 3) according to apnea-hypopnea index. The PPCT, CMCT, and RNFL measurements were performed by using spectral domain optical coherence tomography with enhanced depth imaging technique. The main parameters assessed were PPCT-Temporal, PPCT-Superior, PPCT-Nasal, PPCT-Inferior quadrants, CMCT, and RNFL thicknesses.Results: The PPCT of all quadrants was significantly thicker in the control group compared with the moderate and severe subgroups of OSAHS (p < 0.05). The PPCT-Superior and PPCT-Temporal were significantly thinner in the mild subgroup compared with the control group (p = 0.003 and p = 0.028, respectively). There was no difference between the control and mild groups regarding the RNFL thicknesses except nasal RNFL and inferotemporal RNFL which are thinner in the mild group. The RNFL thicknesses of all quadrants were significantly thicker in the control group compared with moderate and severe subgroups (p < 0.05). The CMCT was significantly thicker in the control group compared with all subgroups of OSAHS (p < 0.05).Conclusions: In OSAHS patients, PPCT, CMCT, and RNFL were significantly thinner compared with the control group. These results may explain why OSAHS patients are prone to normotensive glaucoma.

Yazar Yazgan, Serpil
Erboy, Fatma
Celik, Haci Ugur
Ornek, Tacettin
Ugurbas, Suat Hayri
Kokturk, Firuzan
Ayar, Orhan
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3088
Tek Biçim Adres 10.1080/02713683.2016.1266661
Konu Başlıkları Obstructive sleep apnea-hypopnea syndrome
peripapillary choroidal thickness
retinal nerve fiber layer
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı CURRENT EYE RESEARCH
Dergi Cilt Bilgisi 42
Dergi Sayısı 11
Sayfalar 1552 - 1560
Yayın Yılı 2017
Eser Adı
[dc.title]
Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer in Untreated Patients with Obstructive Sleep Apnea-Hypopnea Syndrome: A Case-Control Study
Yazar
[dc.contributor.author]
Yazgan, Serpil
Yazar
[dc.contributor.author]
Erboy, Fatma
Yazar
[dc.contributor.author]
Celik, Haci Ugur
Yazar
[dc.contributor.author]
Ornek, Tacettin
Yazar
[dc.contributor.author]
Ugurbas, Suat Hayri
Yazar
[dc.contributor.author]
Kokturk, Firuzan
Yazar
[dc.contributor.author]
Ayar, Orhan
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
TAYLOR & FRANCIS INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose: To evaluate peripapillary choroidal thickness (PPCT), central macular choroidal thickness (CMCT), and retinal nerve fiber layer (RNFL) thickness in untreated patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).Methods: This prospective, randomized, and comparative study was conducted in a university ophthalmology clinic. 106 eyes of 106 patients with OSAHS and 44 eyes of 44 healthy individuals were evaluated in this study. Only right eyes were evaluated. The patients with OSAHS were divided into three groups as mild (group 1), moderate (group 2), and severe (group 3) according to apnea-hypopnea index. The PPCT, CMCT, and RNFL measurements were performed by using spectral domain optical coherence tomography with enhanced depth imaging technique. The main parameters assessed were PPCT-Temporal, PPCT-Superior, PPCT-Nasal, PPCT-Inferior quadrants, CMCT, and RNFL thicknesses.Results: The PPCT of all quadrants was significantly thicker in the control group compared with the moderate and severe subgroups of OSAHS (p < 0.05). The PPCT-Superior and PPCT-Temporal were significantly thinner in the mild subgroup compared with the control group (p = 0.003 and p = 0.028, respectively). There was no difference between the control and mild groups regarding the RNFL thicknesses except nasal RNFL and inferotemporal RNFL which are thinner in the mild group. The RNFL thicknesses of all quadrants were significantly thicker in the control group compared with moderate and severe subgroups (p < 0.05). The CMCT was significantly thicker in the control group compared with all subgroups of OSAHS (p < 0.05).Conclusions: In OSAHS patients, PPCT, CMCT, and RNFL were significantly thinner compared with the control group. These results may explain why OSAHS patients are prone to normotensive glaucoma.
Açıklama
[dc.description]
WOS: 000415906800020
Açıklama
[dc.description]
PubMed: 28910165
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Obstructive sleep apnea-hypopnea syndrome
Konu Başlıkları
[dc.subject]
peripapillary choroidal thickness
Konu Başlıkları
[dc.subject]
retinal nerve fiber layer
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0271-3683
ISSN
[dc.identifier.issn]
1460-2202
İlk Sayfa Sayısı
[dc.identifier.startpage]
1552
Son Sayfa Sayısı
[dc.identifier.endpage]
1560
Dergi Adı
[dc.relation.journal]
CURRENT EYE RESEARCH
Dergi Sayısı
[dc.identifier.issue]
11
Dergi Cilt Bilgisi
[dc.identifier.volume]
42
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1080/02713683.2016.1266661
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3088
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
8
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
06 Şubat 2024 21:59
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control significantly patients compared subgroups (group thicker moderate severe thicknesses quadrants thinner thickness apnea-hypopnea groups PPCT-Temporal PPCT-Superior evaluated choroidal Results PPCT-Inferior normotensive glaucoma PPCT-Nasal assessed parameters explain results between subgroup imaging respectively) difference regarding except
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