Is computed tomography necessary to determine liver injury in pediatric trauma patients with negative ultrasonography?

Purpose Abdominal trauma is the third most common cause of all trauma-related deaths in children. Liver injury is the second most common, but the most fatal injury associated with abdomen trauma. Because the liver enzymes have high sensitivity and specificity, the use of tomography has been discussed for accurate diagnosis of liver injury. Methods Our study was based on retrospective analyses of hemodynamically stabil patients under the age of 18 who were admitted to the emergency department with blunt abdominal trauma. Results Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were significantly higher as a result of liver injury. In the patients whose AST and ALT levels were lower than 40 IU/L, no liver injury was observed in the contrast-enhanced computed tomography (CT). No liver injury was detected in the patients with AST levels lower than 100 IU/L. Liver injury was detected with contrast-enhanced CT in only one patient whose ALT level was lower than 100 IU/L, but ultrasonography initially detected liver injury in this patient. Conclusions According to our findings, abdominal CT may not be necessary to detect liver injury if the patient has ALT and AST levels below 100 IU/L with a negative abdominal USG at admission and during follow-up.

Yazar Kaya, U.
Cavus, U. Y.
Karakilic, M. E.
Erdem, A. B.
Aydin, K.
Isik, B.
Abacioglu, Serkan
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2845
Tek Biçim Adres 10.1007/s00068-013-0322-2
Konu Başlıkları Pediatric abdominal trauma
Liver enzyme
Liver injury
Ultrasonography
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
Dergi Cilt Bilgisi 39
Dergi Sayısı 6
Sayfalar 641 - 646
Yayın Yılı 2013
Eser Adı
[dc.title]
Is computed tomography necessary to determine liver injury in pediatric trauma patients with negative ultrasonography?
Yazar
[dc.contributor.author]
Kaya, U.
Yazar
[dc.contributor.author]
Cavus, U. Y.
Yazar
[dc.contributor.author]
Karakilic, M. E.
Yazar
[dc.contributor.author]
Erdem, A. B.
Yazar
[dc.contributor.author]
Aydin, K.
Yazar
[dc.contributor.author]
Isik, B.
Yazar
[dc.contributor.author]
Abacioglu, Serkan
Yayın Yılı
[dc.date.issued]
2013
Yayıncı
[dc.publisher]
SPRINGER HEIDELBERG
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose Abdominal trauma is the third most common cause of all trauma-related deaths in children. Liver injury is the second most common, but the most fatal injury associated with abdomen trauma. Because the liver enzymes have high sensitivity and specificity, the use of tomography has been discussed for accurate diagnosis of liver injury. Methods Our study was based on retrospective analyses of hemodynamically stabil patients under the age of 18 who were admitted to the emergency department with blunt abdominal trauma. Results Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were significantly higher as a result of liver injury. In the patients whose AST and ALT levels were lower than 40 IU/L, no liver injury was observed in the contrast-enhanced computed tomography (CT). No liver injury was detected in the patients with AST levels lower than 100 IU/L. Liver injury was detected with contrast-enhanced CT in only one patient whose ALT level was lower than 100 IU/L, but ultrasonography initially detected liver injury in this patient. Conclusions According to our findings, abdominal CT may not be necessary to detect liver injury if the patient has ALT and AST levels below 100 IU/L with a negative abdominal USG at admission and during follow-up.
Açıklama
[dc.description]
WOS: 000328083700012
Açıklama
[dc.description]
PubMed: 26815549
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Pediatric abdominal trauma
Konu Başlıkları
[dc.subject]
Liver enzyme
Konu Başlıkları
[dc.subject]
Liver injury
Konu Başlıkları
[dc.subject]
Ultrasonography
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1863-9933
ISSN
[dc.identifier.issn]
1863-9941
İlk Sayfa Sayısı
[dc.identifier.startpage]
641
Son Sayfa Sayısı
[dc.identifier.endpage]
646
Dergi Adı
[dc.relation.journal]
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
39
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1007/s00068-013-0322-2
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2845
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
5
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
29 Ocak 2024 05:43
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Tıklayınız
injury levels patient trauma detected patients abdominal contrast-enhanced aminotransferase tomography common According negative admission observed during follow-up result Conclusions higher initially ultrasonography findings detect necessary computed Purpose emergency significantly Because discussed specificity sensitivity enzymes abdomen
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