Low magnesium levels an important new prognostic parameter can be overlooked in patients with Fournier's gangrene: a multicentric study

Introduction We evaluated low magnesium levels and three different scoring systems including the Fournier's Gangrene Severity Index (FGSI), the Uludag Fournier's Gangrene Severity Index (UFGSI), and the Charlson Comorbidity Index (CCI) for predicting mortality in a multicentric, large patient population with FG. Methods The medical records of 99 FG patients who were treated and followed up in different clinics were reviewed. The biochemical, hematological, and bacteriological results from the admission evaluation were recorded. The CCI, FGSI, and UFGSI were evaluated and stratified by survival. Results The results were evaluated for the following patients: the survivors (n = 82) and the nonsurvivors (n = 17). The magnesium level for the survivors and nonsurvivors was 2.09 +/- 0.28 and 1.68 +/- 0.23, respectively (p 0.004). The admission FGSI, UFGSI, and CCI scores were significantly higher in nonsurvivors (p 0.001, p 0.001, p < 0.001, respectively). The receiver operating characteristics analysis revealed that the UFGSI was more powerful than the FGSI. The hypomagnesemia, low hemoglobin and hematocrit, low albumin and HCO3 levels; high alkaline phosphatase; and the high heart and respiratory rates, an FGSI >9, rectal involvement, and a high CCI were associated with a worse prognosis. Conclusion Low magnesium levels might be an important parameter for a worse FG prognosis. Monitoring the serum magnesium levels might have prognostic and therapeutic implications in patients with FG. High CCI, FGSI, and UFGSI scores might be associated with a worse prognosis in patients with FG. The UFGSI might be more powerful scoring system than the FGSI.

Yazar Erol, Bulent
Tuncel, Altug
Tok, Adem
Hanci, Volkan
Sari, Utku
Sendogan, Furkan
Budak, Salih
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2898
Tek Biçim Adres 10.1007/s11255-015-1131-9
Konu Başlıkları Fournier's Gangrene
Magnesium
Index
Prognosis
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı INTERNATIONAL UROLOGY AND NEPHROLOGY
Dergi Cilt Bilgisi 47
Dergi Sayısı 12
Sayfalar 1939 - 1945
Yayın Yılı 2015
Eser Adı
[dc.title]
Low magnesium levels an important new prognostic parameter can be overlooked in patients with Fournier's gangrene: a multicentric study
Yazar
[dc.contributor.author]
Erol, Bulent
Yazar
[dc.contributor.author]
Tuncel, Altug
Yazar
[dc.contributor.author]
Tok, Adem
Yazar
[dc.contributor.author]
Hanci, Volkan
Yazar
[dc.contributor.author]
Sari, Utku
Yazar
[dc.contributor.author]
Sendogan, Furkan
Yazar
[dc.contributor.author]
Budak, Salih
Yayın Yılı
[dc.date.issued]
2015
Yayıncı
[dc.publisher]
SPRINGER
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Introduction We evaluated low magnesium levels and three different scoring systems including the Fournier's Gangrene Severity Index (FGSI), the Uludag Fournier's Gangrene Severity Index (UFGSI), and the Charlson Comorbidity Index (CCI) for predicting mortality in a multicentric, large patient population with FG. Methods The medical records of 99 FG patients who were treated and followed up in different clinics were reviewed. The biochemical, hematological, and bacteriological results from the admission evaluation were recorded. The CCI, FGSI, and UFGSI were evaluated and stratified by survival. Results The results were evaluated for the following patients: the survivors (n = 82) and the nonsurvivors (n = 17). The magnesium level for the survivors and nonsurvivors was 2.09 +/- 0.28 and 1.68 +/- 0.23, respectively (p 0.004). The admission FGSI, UFGSI, and CCI scores were significantly higher in nonsurvivors (p 0.001, p 0.001, p < 0.001, respectively). The receiver operating characteristics analysis revealed that the UFGSI was more powerful than the FGSI. The hypomagnesemia, low hemoglobin and hematocrit, low albumin and HCO3 levels; high alkaline phosphatase; and the high heart and respiratory rates, an FGSI >9, rectal involvement, and a high CCI were associated with a worse prognosis. Conclusion Low magnesium levels might be an important parameter for a worse FG prognosis. Monitoring the serum magnesium levels might have prognostic and therapeutic implications in patients with FG. High CCI, FGSI, and UFGSI scores might be associated with a worse prognosis in patients with FG. The UFGSI might be more powerful scoring system than the FGSI.
Açıklama
[dc.description]
WOS: 000369016000003
Açıklama
[dc.description]
PubMed: 26494633
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Fournier's Gangrene
Konu Başlıkları
[dc.subject]
Magnesium
Konu Başlıkları
[dc.subject]
Index
Konu Başlıkları
[dc.subject]
Prognosis
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0301-1623
ISSN
[dc.identifier.issn]
1573-2584
İlk Sayfa Sayısı
[dc.identifier.startpage]
1939
Son Sayfa Sayısı
[dc.identifier.endpage]
1945
Dergi Adı
[dc.relation.journal]
INTERNATIONAL UROLOGY AND NEPHROLOGY
Dergi Sayısı
[dc.identifier.issue]
12
Dergi Cilt Bilgisi
[dc.identifier.volume]
47
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1007/s11255-015-1131-9
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2898
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
186
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Haziran 2024 07:43
Google Kontrol
Tıklayınız
patients magnesium levels prognosis nonsurvivors evaluated results admission powerful survivors scores associated Gangrene different scoring Severity Fournier rectal operating revealed analysis characteristics respectively) receiver implications system higher significantly therapeutic involvement Conclusion respiratory phosphatase alkaline albumin
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms