The association of eccentricity indexes with cardiac biomarkers in normotensive acute pulmonary embolism patients: an observational study

Objective: The present study aims at investigating the association of systolic and diastolic eccentricity indexes with cardiac biomarkers in hemodynamically stable patients with acute pulmonary embolism (APE). Methods: Thirty hemodynamically stable (systolic blood pressure >90 mmHg) patients with APE (17M, mean age 61.67 +/- 17.6 years) were included in this cross-sectional observational study. The associations of serum troponin I, D-dimer, brain natriuretic peptide (BNP) and heart type fatty acid binding protein (hFABP) levels with systolic and diastolic eccentricity indices, tricuspid annular plane systolic excursion (TAPSE), myocardial performance index (MPI), systolic pulmonary artery pressure and the index of the inferior vena cava were investigated. The relationships between parameters were evaluated by Pearson and Spearman correlation analysis according to the distribution of data. Results: Correlation analysis revealed that the most significant relationship between cardiac biomarkers and echocardiographic measurements was in the BNP value. Meanwhile, systolic and diastolic eccentricity indexes were found to have significant correlation with serum troponin I (respectively r=0.470, p=0.009/r=0.310, p=0.095) and BNP (respectively r=0.402, p=0.028/r=0.384, p=0.036) values. On the other hand, elevated D-dimer levels led to statistical significance in none of the echocardiographic parameters. Conclusion: According to our results, hFABP was rarely positive in normotensive patients with APE. An elevated D-dimer alone was not significant in predicting RVD. Eccentricity indexes revealed significant relationship with BNP and troponin I values. The results obtained indicate that early echocardiographic evaluation is important in patients with abnormal cardiac biomarkers. (Anadolu Kardiyol Derg 2013; 13: 108-14)

Yazar Cetiner, Mehmet Ali
Sayin, Muhammet Rasit
Yildirim, Nesligul
Karabag, Turgut
Aydin, Mustafa
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3457
Tek Biçim Adres 10.5152/akd.2013.033
Konu Başlıkları Acute pulmonary embolism
systolic eccentricity index
diastolic eccentricity index
BNP
troponin I
hFABP
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı ANATOLIAN JOURNAL OF CARDIOLOGY
Dergi Cilt Bilgisi 13
Dergi Sayısı 2
Sayfalar 108 - 114
Yayın Yılı 2013
Eser Adı
[dc.title]
The association of eccentricity indexes with cardiac biomarkers in normotensive acute pulmonary embolism patients: an observational study
Yazar
[dc.contributor.author]
Cetiner, Mehmet Ali
Yazar
[dc.contributor.author]
Sayin, Muhammet Rasit
Yazar
[dc.contributor.author]
Yildirim, Nesligul
Yazar
[dc.contributor.author]
Karabag, Turgut
Yazar
[dc.contributor.author]
Aydin, Mustafa
Yayın Yılı
[dc.date.issued]
2013
Yayıncı
[dc.publisher]
TURKISH SOC CARDIOLOGY
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective: The present study aims at investigating the association of systolic and diastolic eccentricity indexes with cardiac biomarkers in hemodynamically stable patients with acute pulmonary embolism (APE). Methods: Thirty hemodynamically stable (systolic blood pressure >90 mmHg) patients with APE (17M, mean age 61.67 +/- 17.6 years) were included in this cross-sectional observational study. The associations of serum troponin I, D-dimer, brain natriuretic peptide (BNP) and heart type fatty acid binding protein (hFABP) levels with systolic and diastolic eccentricity indices, tricuspid annular plane systolic excursion (TAPSE), myocardial performance index (MPI), systolic pulmonary artery pressure and the index of the inferior vena cava were investigated. The relationships between parameters were evaluated by Pearson and Spearman correlation analysis according to the distribution of data. Results: Correlation analysis revealed that the most significant relationship between cardiac biomarkers and echocardiographic measurements was in the BNP value. Meanwhile, systolic and diastolic eccentricity indexes were found to have significant correlation with serum troponin I (respectively r=0.470, p=0.009/r=0.310, p=0.095) and BNP (respectively r=0.402, p=0.028/r=0.384, p=0.036) values. On the other hand, elevated D-dimer levels led to statistical significance in none of the echocardiographic parameters. Conclusion: According to our results, hFABP was rarely positive in normotensive patients with APE. An elevated D-dimer alone was not significant in predicting RVD. Eccentricity indexes revealed significant relationship with BNP and troponin I values. The results obtained indicate that early echocardiographic evaluation is important in patients with abnormal cardiac biomarkers. (Anadolu Kardiyol Derg 2013; 13: 108-14)
Açıklama
[dc.description]
WOS: 000317362300003
Açıklama
[dc.description]
PubMed: 23228971
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
tur
Konu Başlıkları
[dc.subject]
Acute pulmonary embolism
Konu Başlıkları
[dc.subject]
systolic eccentricity index
Konu Başlıkları
[dc.subject]
diastolic eccentricity index
Konu Başlıkları
[dc.subject]
BNP
Konu Başlıkları
[dc.subject]
troponin I
Konu Başlıkları
[dc.subject]
hFABP
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
2149-2263
ISSN
[dc.identifier.issn]
2149-2271
İlk Sayfa Sayısı
[dc.identifier.startpage]
108
Son Sayfa Sayısı
[dc.identifier.endpage]
114
Dergi Adı
[dc.relation.journal]
ANATOLIAN JOURNAL OF CARDIOLOGY
Dergi Sayısı
[dc.identifier.issue]
2
Dergi Cilt Bilgisi
[dc.identifier.volume]
13
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.5152/akd.2013.033
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3457
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
19
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
06 Şubat 2024 19:18
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systolic significant patients echocardiographic biomarkers D-dimer indexes cardiac eccentricity diastolic troponin (respectively results elevated revealed pulmonary pressure values between parameters relationship levels stable hemodynamically correlation analysis 028/r=0 measurements 009/r=0 Meanwhile Objective predicting Kardiyol (Anadolu abnormal
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