Can Teicoplanin Be an Effective Choice for Antibiotic-Impregnated Cement Spacer in Two-Stage Revision Total Knee Arthroplasty?

The main purpose of this study was to evaluate the clinical results of two-stage revision total knee arthroplasty using a teicoplanin-impregnated cement spacer for infected primary total knee replacements. Twenty-five patients operated between 2005 and 2012 were included in this study. At the clinical status analysis, rate of infection eradication was assessed, physical examination was performed, Knee Society Score (KSS) was noted, isolated microorganisms were recorded, and the radiographic evaluation was performed. The mean KSS improved from 40 (range, 25-69) preoperatively to 77 (range, 32-96) at the latest follow-up (p < 0.05). Methicillin-resistant Staphylococcus epidermidis was isolated in 9 of 25 patients as the most frequently isolated pathogen, and the other isolated pathogens were methicillin-susceptible S. epidermidis, methicillin-resistant Staphylococcus aureus, and methicillin-susceptible S. aureus. Infection was successfully eradicated in 24 of 25 patients. Two-stage revision of the infected primary knee replacement is a time-consuming but a reliable procedure with high rates of success. Teicoplanin was found to be an effective choice for antibiotic-impregnated cement spacer applied for the eradication of the infection.

Yazar Buyuk, Abdul Fettah
Sofu, Hakan
Camurcu, Ismet Yalkin
Ucpunar, Hanifi
Kaygusuz, Mehmet Akif
Sahin, Vedat
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2192
Tek Biçim Adres 10.1055/s-0036-1584535
Konu Başlıkları Knee arthroplasty
infection.
two-stage revision
teicoplanin
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı JOURNAL OF KNEE SURGERY
Dergi Cilt Bilgisi 30
Dergi Sayısı 3
Sayfalar 283 - 287
Yayın Yılı 2017
Eser Adı
[dc.title]
Can Teicoplanin Be an Effective Choice for Antibiotic-Impregnated Cement Spacer in Two-Stage Revision Total Knee Arthroplasty?
Yazar
[dc.contributor.author]
Buyuk, Abdul Fettah
Yazar
[dc.contributor.author]
Sofu, Hakan
Yazar
[dc.contributor.author]
Camurcu, Ismet Yalkin
Yazar
[dc.contributor.author]
Ucpunar, Hanifi
Yazar
[dc.contributor.author]
Kaygusuz, Mehmet Akif
Yazar
[dc.contributor.author]
Sahin, Vedat
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
GEORG THIEME VERLAG KG
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The main purpose of this study was to evaluate the clinical results of two-stage revision total knee arthroplasty using a teicoplanin-impregnated cement spacer for infected primary total knee replacements. Twenty-five patients operated between 2005 and 2012 were included in this study. At the clinical status analysis, rate of infection eradication was assessed, physical examination was performed, Knee Society Score (KSS) was noted, isolated microorganisms were recorded, and the radiographic evaluation was performed. The mean KSS improved from 40 (range, 25-69) preoperatively to 77 (range, 32-96) at the latest follow-up (p < 0.05). Methicillin-resistant Staphylococcus epidermidis was isolated in 9 of 25 patients as the most frequently isolated pathogen, and the other isolated pathogens were methicillin-susceptible S. epidermidis, methicillin-resistant Staphylococcus aureus, and methicillin-susceptible S. aureus. Infection was successfully eradicated in 24 of 25 patients. Two-stage revision of the infected primary knee replacement is a time-consuming but a reliable procedure with high rates of success. Teicoplanin was found to be an effective choice for antibiotic-impregnated cement spacer applied for the eradication of the infection.
Açıklama
[dc.description]
WOS: 000395525400016
Açıklama
[dc.description]
PubMed: 27362924
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Knee arthroplasty
Konu Başlıkları
[dc.subject]
infection.
Konu Başlıkları
[dc.subject]
two-stage revision
Konu Başlıkları
[dc.subject]
teicoplanin
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1538-8506
ISSN
[dc.identifier.issn]
1938-2480
İlk Sayfa Sayısı
[dc.identifier.startpage]
283
Son Sayfa Sayısı
[dc.identifier.endpage]
287
Dergi Adı
[dc.relation.journal]
JOURNAL OF KNEE SURGERY
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
30
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1055/s-0036-1584535
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2192
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
17
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
01 Şubat 2024 22:53
Google Kontrol
Tıklayınız
isolated patients methicillin-susceptible aureus performed eradication infection (range epidermidis Staphylococcus primary cement clinical revision infected spacer pathogens pathogen frequently antibiotic-impregnated effective success applied Methicillin-resistant choice methicillin-resistant replacement procedure reliable time-consuming Two-stage eradicated Teicoplanin successfully Infection
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms