Determination of biogenic amines in licorice (Glycyrrhiza glabra) by ion-pair extraction and liquid chromatography-tandem mass spectrometry

BACKGROUND: Ion-pair extraction combined with liquid chromatography-tandem mass spectrometry method has been proposed for the determination of biogenic amines in licorice samples. RESULTS: Limit of detection and limit of quantitation for the biogenic amines were 1.4-2.7 and 4.7-9.1 ng mL(-1), respectively. Relative standard deviations based on five replicate extraction of 100 ng mL(-1) of each biogenic amine were <4.7% for intra-day and 7.4% for inter-day precision. The method described in this study has been shown to be in accordance with satisfactory accuracy and good reproducibility for the quantitative determination of biogenic amines in licorice samples. Nine biogenic amines (putrescine, cadaverine, histamine, spermine, spermidine, tyramine, tryptamine, agmatine and phenylethylamine) were detected in licorice samples and total biogenic amine concentrations were determined at 369 ng mL(-1) in fresh and 3532 ng mL(-1) in non-fresh licorice samples. Putrescine was found at the highest concentrations to be up to 704 ng mL(-1) in all the analyzed samples, followed by tyramine (675 ng mL(-1)) and tryptamine (282 ng mL(-1)). Putrescine, tyramine and spermine concentrations were dramatically increased, whereas agmatine concentration was significantly decreased, in non-fresh licorice samples compared to fresh ones. CONCLUSION: The consumption of freshly prepared licorice is recommended because of the relatively low concentration of total biogenic amines. (C) 2016 Society of Chemical Industry

Yazar Ata, Sevket
Akyuz, Mehmet
Cabuk, Hasan
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2358
Tek Biçim Adres 10.1002/jsfa.7881
Konu Başlıkları licorice
biogenic amines
ion-pair extraction
LC-MS/MS
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
Dergi Cilt Bilgisi 97
Dergi Sayısı 5
Sayfalar 1427 - 1432
Yayın Yılı 2017
Eser Adı
[dc.title]
Determination of biogenic amines in licorice (Glycyrrhiza glabra) by ion-pair extraction and liquid chromatography-tandem mass spectrometry
Yazar
[dc.contributor.author]
Ata, Sevket
Yazar
[dc.contributor.author]
Akyuz, Mehmet
Yazar
[dc.contributor.author]
Cabuk, Hasan
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
WILEY
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
BACKGROUND: Ion-pair extraction combined with liquid chromatography-tandem mass spectrometry method has been proposed for the determination of biogenic amines in licorice samples. RESULTS: Limit of detection and limit of quantitation for the biogenic amines were 1.4-2.7 and 4.7-9.1 ng mL(-1), respectively. Relative standard deviations based on five replicate extraction of 100 ng mL(-1) of each biogenic amine were <4.7% for intra-day and 7.4% for inter-day precision. The method described in this study has been shown to be in accordance with satisfactory accuracy and good reproducibility for the quantitative determination of biogenic amines in licorice samples. Nine biogenic amines (putrescine, cadaverine, histamine, spermine, spermidine, tyramine, tryptamine, agmatine and phenylethylamine) were detected in licorice samples and total biogenic amine concentrations were determined at 369 ng mL(-1) in fresh and 3532 ng mL(-1) in non-fresh licorice samples. Putrescine was found at the highest concentrations to be up to 704 ng mL(-1) in all the analyzed samples, followed by tyramine (675 ng mL(-1)) and tryptamine (282 ng mL(-1)). Putrescine, tyramine and spermine concentrations were dramatically increased, whereas agmatine concentration was significantly decreased, in non-fresh licorice samples compared to fresh ones. CONCLUSION: The consumption of freshly prepared licorice is recommended because of the relatively low concentration of total biogenic amines. (C) 2016 Society of Chemical Industry
Açıklama
[dc.description]
WOS: 000397419600007
Açıklama
[dc.description]
PubMed: 27381870
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
licorice
Konu Başlıkları
[dc.subject]
biogenic amines
Konu Başlıkları
[dc.subject]
ion-pair extraction
Konu Başlıkları
[dc.subject]
LC-MS/MS
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0022-5142
ISSN
[dc.identifier.issn]
1097-0010
Sponsor YAYINCI
[dc.description.sponsorship]
Bulent Ecevit UniversityBulent Ecevit University
Sponsor YAYINCI
[dc.description.sponsorship]
The authors wish to thank Bulent Ecevit University for the opportunity and support to carry out this research. The authors also thank the Editing Office of Bulent Ecevit University for linguistic corrections.
İlk Sayfa Sayısı
[dc.identifier.startpage]
1427
Son Sayfa Sayısı
[dc.identifier.endpage]
1432
Dergi Adı
[dc.relation.journal]
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
97
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1002/jsfa.7881
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2358
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
27
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 09:46
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biogenic samples licorice mL(-1) amines concentrations tyramine Putrescine non-fresh mL(-1)) concentration agmatine spermine determination extraction method tryptamine significantly compared relatively determined prepared Society detected phenylethylamine) consumption Chemical freshly whereas increased dramatically recommended decreased because followed
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