Nephrolithiasis in ankylosing spondylitis and its relationship with disease assessment scales

OBJECTIVE: The aim of this study was to investigate the frequency of renal calculi in patients with ankylosing spondylitis (AS) and to determine its relationship with disease assessment variables. METHODS: The study was designed retrospectively, and it included a cohort of 320 patients with AS diagnosed using the Modified New York Criteria. A total of 119 patients who underwent renal ultrasonography (USG), in who the erythrocyte sedimentation rate, C-reactive protein, blood calcium, phosphorus, Vitamin D, parathormone, and urinary calcium excretion were measured, and who also had lateral cervical and lumbar radiography in the same time period were extracted from the cohort. All patients' demographic characteristics and the results of blood and urine tests were recorded. The Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Mobility Index (BASMI), and Modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) were evaluated in all patients. RESULTS: Thirteen of the 119 patients had renal calculi confirmed by USG data. The frequency of nephrolithiasis detected by USG was 10.9% in patients with AS. The disease lasted significantly longer in patients with renal calculi ([nephrolithiasis (+): 18.39 +/- 8.72 years; nephrolithiasis (-): 12.02 +/- 8.43 years, p=0.01]). The BASMI total score was significantly higher in the group of patients with renal calculi. There was not any significant difference in terms of blood samples, HLA-B27, BASDAI, BASFI, and mSASSS between groups. CONCLUSION: The frequency of renal stones is increased in patients with AS compared to healthy population. Especially patients who had AS for a long time and higher BASMI values are more susceptible to renal calculi. It is important to point out that the results of this type of studies would be more reliable if the study is conducted on large patient groups and population-based prevalence.

Yazar Rezvani, Aylin
Aktas, Ilknur
Tastekin, Nurettin
Celiker, Reyhan
Sarikaya, Selda
Dursun, Erbil
Ozdolap, Senay
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2987
Tek Biçim Adres 10.14744/nci.2018.58219
Konu Başlıkları Ankylosing spondylitis
BASDAI
BASFI
BASMI
mSASSS
nephroilitasiz
urolithiasis
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı NORTHERN CLINICS OF ISTANBUL
Dergi Cilt Bilgisi 6
Dergi Sayısı 3
Sayfalar 254 - 259
Yayın Yılı 2019
Eser Adı
[dc.title]
Nephrolithiasis in ankylosing spondylitis and its relationship with disease assessment scales
Yazar
[dc.contributor.author]
Rezvani, Aylin
Yazar
[dc.contributor.author]
Aktas, Ilknur
Yazar
[dc.contributor.author]
Tastekin, Nurettin
Yazar
[dc.contributor.author]
Celiker, Reyhan
Yazar
[dc.contributor.author]
Sarikaya, Selda
Yazar
[dc.contributor.author]
Dursun, Erbil
Yazar
[dc.contributor.author]
Ozdolap, Senay
Yayın Yılı
[dc.date.issued]
2019
Yayıncı
[dc.publisher]
KARE PUBL
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
OBJECTIVE: The aim of this study was to investigate the frequency of renal calculi in patients with ankylosing spondylitis (AS) and to determine its relationship with disease assessment variables. METHODS: The study was designed retrospectively, and it included a cohort of 320 patients with AS diagnosed using the Modified New York Criteria. A total of 119 patients who underwent renal ultrasonography (USG), in who the erythrocyte sedimentation rate, C-reactive protein, blood calcium, phosphorus, Vitamin D, parathormone, and urinary calcium excretion were measured, and who also had lateral cervical and lumbar radiography in the same time period were extracted from the cohort. All patients' demographic characteristics and the results of blood and urine tests were recorded. The Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Mobility Index (BASMI), and Modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) were evaluated in all patients. RESULTS: Thirteen of the 119 patients had renal calculi confirmed by USG data. The frequency of nephrolithiasis detected by USG was 10.9% in patients with AS. The disease lasted significantly longer in patients with renal calculi ([nephrolithiasis (+): 18.39 +/- 8.72 years; nephrolithiasis (-): 12.02 +/- 8.43 years, p=0.01]). The BASMI total score was significantly higher in the group of patients with renal calculi. There was not any significant difference in terms of blood samples, HLA-B27, BASDAI, BASFI, and mSASSS between groups. CONCLUSION: The frequency of renal stones is increased in patients with AS compared to healthy population. Especially patients who had AS for a long time and higher BASMI values are more susceptible to renal calculi. It is important to point out that the results of this type of studies would be more reliable if the study is conducted on large patient groups and population-based prevalence.
Açıklama
[dc.description]
WOS: 000486393500008
Açıklama
[dc.description]
PubMed: 31650112
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Ankylosing spondylitis
Konu Başlıkları
[dc.subject]
BASDAI
Konu Başlıkları
[dc.subject]
BASFI
Konu Başlıkları
[dc.subject]
BASMI
Konu Başlıkları
[dc.subject]
mSASSS
Konu Başlıkları
[dc.subject]
nephroilitasiz
Konu Başlıkları
[dc.subject]
urolithiasis
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
2148-4902
İlk Sayfa Sayısı
[dc.identifier.startpage]
254
Son Sayfa Sayısı
[dc.identifier.endpage]
259
Dergi Adı
[dc.relation.journal]
NORTHERN CLINICS OF ISTANBUL
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
6
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.14744/nci.2018.58219
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2987
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
18
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 07:23
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Tıklayınız
patients calculi Ankylosing Spondylitis frequency significantly Modified groups higher calcium nephrolithiasis results cohort disease difference significant ([nephrolithiasis longer lasted OBJECTIVE studies reliable conducted patient population-based prevalence important susceptible samples stones HLA-B27 BASDAI mSASSS between CONCLUSION
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