Serum Asymmetric Dimethylarginine, Nitrate, Vitamin B-12, and Homocysteine Levels in Individuals with Pulmonary Embolism

We aimed to analyze the pre- and posttreatment serum asymmetric dimethylarginine (ADMA), nitrate (NO3), vitamin B-12 and homocysteine levels in pulmonary embolism (PTE) patients and to determine the prognostic value of these variables in predicting chronic thromboembolic pulmonary hypertension (CTEPH). This study was conducted in 64 patients. The patients were classified into the two groups: patients with normal pulmonary artery pressure (PAP) (group I) and patients with high PAP with persistent lung perfusion defects or who died at the end of 3 months of therapy (group II). We found statistically significant differences between two groups with respect to the partial oxygen pressure, the oxygen saturation, and the PAP, but there was no difference between the two groups with respect to the pretreatment ADMA, NO3, or homocysteine levels. The vitamin B-12 levels were higher in group II. The NO3 levels increased and the ADMA and vitamin B-12 levels decreased with treatment in both groups. These results suggest that these parameters are not predictive of the development of CTEPH.

Yazar Altuntas, Murat
Atalay, Figen
Can, Murat
Altin, Remzi
Tor, Meltem
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3308
Tek Biçim Adres 10.1155/2011/215057
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı MEDIATORS OF INFLAMMATION
Sayfalar -
Yayın Yılı 2011
Eser Adı
[dc.title]
Serum Asymmetric Dimethylarginine, Nitrate, Vitamin B-12, and Homocysteine Levels in Individuals with Pulmonary Embolism
Yazar
[dc.contributor.author]
Altuntas, Murat
Yazar
[dc.contributor.author]
Atalay, Figen
Yazar
[dc.contributor.author]
Can, Murat
Yazar
[dc.contributor.author]
Altin, Remzi
Yazar
[dc.contributor.author]
Tor, Meltem
Yayın Yılı
[dc.date.issued]
2011
Yayıncı
[dc.publisher]
HINDAWI PUBLISHING CORPORATION
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
We aimed to analyze the pre- and posttreatment serum asymmetric dimethylarginine (ADMA), nitrate (NO3), vitamin B-12 and homocysteine levels in pulmonary embolism (PTE) patients and to determine the prognostic value of these variables in predicting chronic thromboembolic pulmonary hypertension (CTEPH). This study was conducted in 64 patients. The patients were classified into the two groups: patients with normal pulmonary artery pressure (PAP) (group I) and patients with high PAP with persistent lung perfusion defects or who died at the end of 3 months of therapy (group II). We found statistically significant differences between two groups with respect to the partial oxygen pressure, the oxygen saturation, and the PAP, but there was no difference between the two groups with respect to the pretreatment ADMA, NO3, or homocysteine levels. The vitamin B-12 levels were higher in group II. The NO3 levels increased and the ADMA and vitamin B-12 levels decreased with treatment in both groups. These results suggest that these parameters are not predictive of the development of CTEPH.
Açıklama
[dc.description]
WOS: 000294641200001
Açıklama
[dc.description]
PubMed: 21765614
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0962-9351
Dergi Adı
[dc.relation.journal]
MEDIATORS OF INFLAMMATION
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1155/2011/215057
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3308
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
10
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 23:15
Google Kontrol
Tıklayınız
patients levels groups vitamin pulmonary pressure between respect oxygen (group homocysteine saturation pretreatment difference analyze partial asymmetric differences significant statistically posttreatment higher development predictive parameters suggest therapy results treatment decreased increased months variables prognostic classified
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms