Antibody response following hepatitis B vaccination in dialysis patients: Does depression and life quality matter?
Previously, it was demonstrated that antibody production against hepatitis B virus (HBV) surface antigen (anti-HBs) achieved in hemodialysis patients is suboptimal. Decreased health-related quality of life (HRQOL) and depression is common among hemodialysis patients. This study evaluated whether HRQOL and depressive behavior are associated with antibody response against HBV surface antigen in hemodialysis patients. Depressive symptoms and HRQOL were assessed by Beck Depression Inventory (BDI) and Medical Outcomes Study Short Form (SF-36), respectively. Patients were separated into non-seroconversion (anti-HBs antibody titers <10 IU/L) and seroconversion (anti-HBs antibody titers >10 IU/L) groups. Among 188 patients, 37 (19.7%) were diagnosed as nonresponsive to vaccination (anti-HBs antibody titers <101 U/L). Anti-HBs response is positively associated with Physical Component Summary Score of SF-36 (odds ratio: 1.44; P: 0.009) and albumin (odds ratio: 10.615, P: 0.007), and negatively with BDI score (odds ratio: 0.903, P: 0.007). We concluded that HRQOL and depression is closely related with antibody response following HBV vaccine in hemodialysis patients. (C) 2009 Elsevier Ltd. All rights reserved.
| Yazar |
Afsar, Baris Elsurer, Rengin Eyileten, Tayfun Yilmaz, M. Ilker Caglar, Kayser |
| Yayın Türü | Article |
| Tek Biçim Adres | https://hdl.handle.net/20.500.12628/2096 |
| Tek Biçim Adres | 10.1016/j.vaccine.2009.07.055 |
| Konu Başlıkları |
Antibody
Depression Hemodialysis Hepatitis B virus Quality of life Vaccine |
| Koleksiyonlar |
Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD PubMed İndeksli Yayınlar Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu |
| Dergi Adı | VACCINE |
| Dergi Cilt Bilgisi | 27 |
| Dergi Sayısı | 42 |
| Sayfalar | 5865 - 5869 |
| Yayın Yılı | 2009 |
| Eser Adı [dc.title] | Antibody response following hepatitis B vaccination in dialysis patients: Does depression and life quality matter? |
| Yazar [dc.contributor.author] | Afsar, Baris |
| Yazar [dc.contributor.author] | Elsurer, Rengin |
| Yazar [dc.contributor.author] | Eyileten, Tayfun |
| Yazar [dc.contributor.author] | Yilmaz, M. Ilker |
| Yazar [dc.contributor.author] | Caglar, Kayser |
| Yayın Yılı [dc.date.issued] | 2009 |
| Yayıncı [dc.publisher] | ELSEVIER SCI LTD |
| Yayın Türü [dc.type] | article |
| Özet [dc.description.abstract] | Previously, it was demonstrated that antibody production against hepatitis B virus (HBV) surface antigen (anti-HBs) achieved in hemodialysis patients is suboptimal. Decreased health-related quality of life (HRQOL) and depression is common among hemodialysis patients. This study evaluated whether HRQOL and depressive behavior are associated with antibody response against HBV surface antigen in hemodialysis patients. Depressive symptoms and HRQOL were assessed by Beck Depression Inventory (BDI) and Medical Outcomes Study Short Form (SF-36), respectively. Patients were separated into non-seroconversion (anti-HBs antibody titers <10 IU/L) and seroconversion (anti-HBs antibody titers >10 IU/L) groups. Among 188 patients, 37 (19.7%) were diagnosed as nonresponsive to vaccination (anti-HBs antibody titers <101 U/L). Anti-HBs response is positively associated with Physical Component Summary Score of SF-36 (odds ratio: 1.44; P: 0.009) and albumin (odds ratio: 10.615, P: 0.007), and negatively with BDI score (odds ratio: 0.903, P: 0.007). We concluded that HRQOL and depression is closely related with antibody response following HBV vaccine in hemodialysis patients. (C) 2009 Elsevier Ltd. All rights reserved. |
| Açıklama [dc.description] | WOS: 000270469900022 |
| Açıklama [dc.description] | PubMed: 19654067 |
| Kayıt Giriş Tarihi [dc.date.accessioned] | 2019-12-23 |
| Açık Erişim Tarihi [dc.date.available] | 2019-12-23 |
| Yayın Dili [dc.language.iso] | eng |
| Konu Başlıkları [dc.subject] | Antibody |
| Konu Başlıkları [dc.subject] | Depression |
| Konu Başlıkları [dc.subject] | Hemodialysis |
| Konu Başlıkları [dc.subject] | Hepatitis B virus |
| Konu Başlıkları [dc.subject] | Quality of life |
| Konu Başlıkları [dc.subject] | Vaccine |
| Haklar [dc.rights] | info:eu-repo/semantics/closedAccess |
| ISSN [dc.identifier.issn] | 0264-410X |
| İlk Sayfa Sayısı [dc.identifier.startpage] | 5865 |
| Son Sayfa Sayısı [dc.identifier.endpage] | 5869 |
| Dergi Adı [dc.relation.journal] | VACCINE |
| Dergi Sayısı [dc.identifier.issue] | 42 |
| Dergi Cilt Bilgisi [dc.identifier.volume] | 27 |
| Tek Biçim Adres [dc.identifier.uri] | https://dx.doi.org/10.1016/j.vaccine.2009.07.055 |
| Tek Biçim Adres [dc.identifier.uri] | https://hdl.handle.net/20.500.12628/2096 |
