The aetiology in paediatric aphakic glaucoma

Purpose To investigate the causes of glaucoma in children following removal of cataracts. Methods In total, 24 patients (37 eyes) with uncomplicated congenital cataracts who developed glaucoma following cataract removal were studied retrospectively. Cataract morphology, surgical technique, postoperative complications, time to glaucoma onset, gonioscopic findings, the presence of microcornea, and the histopathologic characteristics of the filtration angle in one case were the studied parameters. Results We found a bimodal onset of glaucoma. Early-onset glaucoma occurred at a mean age of 6 months in 15 eyes and delayed-onset glaucoma at a mean age of 12 years in 22 eyes. Early-onset glaucoma was significantly (P = 0.018) more likely to be due to angle closure. With delayed-onset glaucoma, the filtration angle is open in 86% of eyes and significantly (P = 0.006) more eyes in the delayed-onset group had microcornea. Conclusions Performing cataract surgery very early in life in microphthalmic eyes and leaving residual lens material increases the risk for glaucoma. We recommend a prophylactic iridectomy in eyes at risk for pupillary block. Eyes with delayed-onset glaucoma have open filtration angles but with findings consistent with incomplete development of filtration structures. Early age at cataract extraction and microcornea are risk factors for delayed-onset glaucoma.

Yazar Koc, F.
Kargi, S.
Biglan, A. W.
Chu, C. T.
Davis, J. S.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3447
Tek Biçim Adres 10.1038/sj.eye.6702150
Konu Başlıkları congenital cataract surgery
aphakia
glaucoma
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı EYE
Dergi Cilt Bilgisi 20
Dergi Sayısı 12
Sayfalar 1360 - 1365
Yayın Yılı 2006
Eser Adı
[dc.title]
The aetiology in paediatric aphakic glaucoma
Yazar
[dc.contributor.author]
Koc, F.
Yazar
[dc.contributor.author]
Kargi, S.
Yazar
[dc.contributor.author]
Biglan, A. W.
Yazar
[dc.contributor.author]
Chu, C. T.
Yazar
[dc.contributor.author]
Davis, J. S.
Yayın Yılı
[dc.date.issued]
2006
Yayıncı
[dc.publisher]
NATURE PUBLISHING GROUP
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose To investigate the causes of glaucoma in children following removal of cataracts. Methods In total, 24 patients (37 eyes) with uncomplicated congenital cataracts who developed glaucoma following cataract removal were studied retrospectively. Cataract morphology, surgical technique, postoperative complications, time to glaucoma onset, gonioscopic findings, the presence of microcornea, and the histopathologic characteristics of the filtration angle in one case were the studied parameters. Results We found a bimodal onset of glaucoma. Early-onset glaucoma occurred at a mean age of 6 months in 15 eyes and delayed-onset glaucoma at a mean age of 12 years in 22 eyes. Early-onset glaucoma was significantly (P = 0.018) more likely to be due to angle closure. With delayed-onset glaucoma, the filtration angle is open in 86% of eyes and significantly (P = 0.006) more eyes in the delayed-onset group had microcornea. Conclusions Performing cataract surgery very early in life in microphthalmic eyes and leaving residual lens material increases the risk for glaucoma. We recommend a prophylactic iridectomy in eyes at risk for pupillary block. Eyes with delayed-onset glaucoma have open filtration angles but with findings consistent with incomplete development of filtration structures. Early age at cataract extraction and microcornea are risk factors for delayed-onset glaucoma.
Açıklama
[dc.description]
WOS: 000242746700007
Açıklama
[dc.description]
PubMed: 16284603
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
congenital cataract surgery
Konu Başlıkları
[dc.subject]
aphakia
Konu Başlıkları
[dc.subject]
glaucoma
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0950-222X
ISSN
[dc.identifier.issn]
1476-5454
İlk Sayfa Sayısı
[dc.identifier.startpage]
1360
Son Sayfa Sayısı
[dc.identifier.endpage]
1365
Dergi Adı
[dc.relation.journal]
EYE
Dergi Sayısı
[dc.identifier.issue]
12
Dergi Cilt Bilgisi
[dc.identifier.volume]
20
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1038/sj.eye.6702150
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3447
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
5
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
11 Aralık 2023 07:43
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Tıklayınız
glaucoma delayed-onset filtration microcornea cataract Early-onset significantly findings cataracts following studied removal recommend development structures closure extraction factors incomplete Conclusions consistent iridectomy increases material residual pupillary leaving microphthalmic prophylactic angles surgery Performing likely Purpose surgical
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