Differential diagnosis of bacterial and viral meningitis in childhood acute meningitis: A statistical model

Acute bacterial meningitis (BM) which is a pediatric emergency with high mortality and morbidity, must be diagnosed and treated promptly. There is no unique method to prove or rule out the diagnosis of BM in a patient with cerebrospinal fluid (CSF) findings consistent with BM but negative Gram stain and culture results. For this purpose the combination of CSF parameters are used for diagnosis. The aims of this study were to compare retrospectively the mean leukocyte count, serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), CSF leukocyte and neutrophil, CSF protein and glucose values in 40 bacterial and 29 viral meningitis (VM) patients, ages between 1 month and 14 years, and to develop a statistical model for the differentiation of BM and VM cases. Logistic regression analysis was used to investigate the relationship between BM and age, CRP, ESR, leukocyte count, CSF leukocyte, neutrophil, protein and glucose values. Based on CSF protein and neutrophil ratio which were found as independent variables, the regression model could predict the patients having BM with 95% and viral meningitis with 93.2% accuracy.

Yazar Celik, Nesat
Tanir, Gonul
Aydemir, Cumhur
Tuygun, Nilden
Zorlu, Pelin
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2389
Konu Başlıkları bacterial meningitis
viral meningitis
childhood
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı MIKROBIYOLOJI BULTENI
Dergi Cilt Bilgisi 41
Dergi Sayısı 1
Sayfalar 63 - 69
Yayın Yılı 2007
Eser Adı
[dc.title]
Differential diagnosis of bacterial and viral meningitis in childhood acute meningitis: A statistical model
Yazar
[dc.contributor.author]
Celik, Nesat
Yazar
[dc.contributor.author]
Tanir, Gonul
Yazar
[dc.contributor.author]
Aydemir, Cumhur
Yazar
[dc.contributor.author]
Tuygun, Nilden
Yazar
[dc.contributor.author]
Zorlu, Pelin
Yayın Yılı
[dc.date.issued]
2007
Yayıncı
[dc.publisher]
ANKARA MICROBIOLOGY SOC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Acute bacterial meningitis (BM) which is a pediatric emergency with high mortality and morbidity, must be diagnosed and treated promptly. There is no unique method to prove or rule out the diagnosis of BM in a patient with cerebrospinal fluid (CSF) findings consistent with BM but negative Gram stain and culture results. For this purpose the combination of CSF parameters are used for diagnosis. The aims of this study were to compare retrospectively the mean leukocyte count, serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), CSF leukocyte and neutrophil, CSF protein and glucose values in 40 bacterial and 29 viral meningitis (VM) patients, ages between 1 month and 14 years, and to develop a statistical model for the differentiation of BM and VM cases. Logistic regression analysis was used to investigate the relationship between BM and age, CRP, ESR, leukocyte count, CSF leukocyte, neutrophil, protein and glucose values. Based on CSF protein and neutrophil ratio which were found as independent variables, the regression model could predict the patients having BM with 95% and viral meningitis with 93.2% accuracy.
Açıklama
[dc.description]
WOS: 000246531100007
Açıklama
[dc.description]
PubMed: 17427553
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
tur
Konu Başlıkları
[dc.subject]
bacterial meningitis
Konu Başlıkları
[dc.subject]
viral meningitis
Konu Başlıkları
[dc.subject]
childhood
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0374-9096
İlk Sayfa Sayısı
[dc.identifier.startpage]
63
Son Sayfa Sayısı
[dc.identifier.endpage]
69
Dergi Adı
[dc.relation.journal]
MIKROBIYOLOJI BULTENI
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
41
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2389
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
13
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 10:24
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Tıklayınız
protein leukocyte meningitis neutrophil patients regression between diagnosis bacterial values glucose develop statistical differentiation accuracy having predict variables independent relationship investigate sedimentation analysis Logistic erythrocyte promptly patient method unique treated diagnosed morbidity mortality emergency pediatric
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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