Enhancement kinetics of normal ovaries on dynamic contrast-enhanced MR imaging

Objective: The objective was to determine the enhancement kinetics of the normal ovaries in healthy women on dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging. Method: Twenty-one women who had normal ovulatory cycles (volunteers; mean age = 26.3 years, range = 20-35), normal hormone profile, and apparently normal ovaries on ultrasonographic scan underwent DCE-MR imaging on a 1.5-T system (Philips Medical Systems, Gyroscan Intera, Best, The Netherlands) using a phased array pelvic coil. Sequential images with an imaging time of 14.4 s per dynamic image were acquired before and after injection of a contrast bolus at 30 s and at 1, 2, 3, 4, and 5 min. On postprocessing examination the following measurements were obtained for ovarian and muscle tissue: the signal intensity value per dynamic study, early phase enhancement rate, time to peak enhancement (T-p), and percentage of wash-out at the fifth minute were determined. Data of the ovaries and skeletal muscle were compared using Wilcoxon's rank sum test. Results: Most of the mean values of the postcontrast signal intensity measurements, the mean values of the early phase enhancement rate, and the percentage of wash-out at the fifth minute were found to be significantly higher in ovary than in muscle (p < 0.05). The mean values of T-p, on the other hand, were nonsignificantly lower in ovary than in muscle (p > 0.05). On the examination of the mean signal intensity-time data graphics the ovary showed a tendency toward greater and quicker enhancement and wash-out. Conclusion: In our opinion, DCE-MR imaging, which determines contrast enhancement such as wash-in and wash-out kinetics, can provide knowledge of ovarian vascularization. Thus, by using DCE-MR imaging, determination of these vascularization changes in various ovarian diseases may provide us with additional parameters in the diagnosis of and treatment strategies for ovarian diseases. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

Yazar Gundogdu, Sadi
Erdem, C. Zuhal
Erdem, L. Oktay
Bayar, Ulku
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2548
Tek Biçim Adres 10.1016/j.ejogrb.2006.03.017
Konu Başlıkları ovary
dynamic contrast-enhanced magnetic resonance imaging
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Dergi Cilt Bilgisi 129
Dergi Sayısı 1
Sayfalar 60 - 64
Yayın Yılı 2006
Eser Adı
[dc.title]
Enhancement kinetics of normal ovaries on dynamic contrast-enhanced MR imaging
Yazar
[dc.contributor.author]
Gundogdu, Sadi
Yazar
[dc.contributor.author]
Erdem, C. Zuhal
Yazar
[dc.contributor.author]
Erdem, L. Oktay
Yazar
[dc.contributor.author]
Bayar, Ulku
Yayın Yılı
[dc.date.issued]
2006
Yayıncı
[dc.publisher]
ELSEVIER IRELAND LTD
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective: The objective was to determine the enhancement kinetics of the normal ovaries in healthy women on dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging. Method: Twenty-one women who had normal ovulatory cycles (volunteers; mean age = 26.3 years, range = 20-35), normal hormone profile, and apparently normal ovaries on ultrasonographic scan underwent DCE-MR imaging on a 1.5-T system (Philips Medical Systems, Gyroscan Intera, Best, The Netherlands) using a phased array pelvic coil. Sequential images with an imaging time of 14.4 s per dynamic image were acquired before and after injection of a contrast bolus at 30 s and at 1, 2, 3, 4, and 5 min. On postprocessing examination the following measurements were obtained for ovarian and muscle tissue: the signal intensity value per dynamic study, early phase enhancement rate, time to peak enhancement (T-p), and percentage of wash-out at the fifth minute were determined. Data of the ovaries and skeletal muscle were compared using Wilcoxon's rank sum test. Results: Most of the mean values of the postcontrast signal intensity measurements, the mean values of the early phase enhancement rate, and the percentage of wash-out at the fifth minute were found to be significantly higher in ovary than in muscle (p < 0.05). The mean values of T-p, on the other hand, were nonsignificantly lower in ovary than in muscle (p > 0.05). On the examination of the mean signal intensity-time data graphics the ovary showed a tendency toward greater and quicker enhancement and wash-out. Conclusion: In our opinion, DCE-MR imaging, which determines contrast enhancement such as wash-in and wash-out kinetics, can provide knowledge of ovarian vascularization. Thus, by using DCE-MR imaging, determination of these vascularization changes in various ovarian diseases may provide us with additional parameters in the diagnosis of and treatment strategies for ovarian diseases. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
Açıklama
[dc.description]
WOS: 000242858800011
Açıklama
[dc.description]
PubMed: 16698167
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
ovary
Konu Başlıkları
[dc.subject]
dynamic contrast-enhanced magnetic resonance imaging
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0301-2115
İlk Sayfa Sayısı
[dc.identifier.startpage]
60
Son Sayfa Sayısı
[dc.identifier.endpage]
64
Dergi Adı
[dc.relation.journal]
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
129
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.ejogrb.2006.03.017
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2548
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
13
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 20:59
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Tıklayınız
enhancement imaging ovarian muscle wash-out normal DCE-MR dynamic values signal ovaries contrast measurements provide examination vascularization kinetics minute percentage intensity diseases nonsignificantly Results higher significantly postcontrast Objective intensity-time treatment changes various additional parameters diagnosis strategies
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