Ropivacaine, Articaine or Combination of Ropivacaine and Articaine for Epidural Anesthesia in Cesarean Section: a Randomized, Prospective, Double-Blinded Study

Background and objectives: Initiation of epidural anesthesia with long-lasting local anesthetics consumes a significant amount of time, which could be problematic in busy obstetric anesthesia suites. We have hypothesized that a combination of articaine and ropivacaine provides faster onset and even an early recovery of sensory-motor block characteristics. Methods: Sixty term parturients scheduled to have elective cesarean section were randomly allocated into three groups to receive either 20 mL 2% articaine (Group A), 10 mL 2% articaine + 10 mL 0.75% ropivacaine (Group AR) or 20 mL 0.75% ropivacaine (Group R) via lumbar epidural catheter. The onset time of sensory block to T-10, T-6 and maximum sensory block level, time to two segments regression from maximum sensory block level, onset time and duration of motor block were all recorded. Intraoperative and postoperative additional analgesic requirements were also recorded. Results: Demographic data were similar. The onset times of sensorial block to T-10 and T-6 were significantly shorter in Groups A and AR in comparison with Group R (p < 0.05). The onset times of motor block were similar in all groups, but a more intense motor block was observed in Group R (p < 0.05). Two segments regression time and motor block durations were significantly shorter in Groups A and AR in comparison with Group R (p < 0.05). Intraoperative supplementary analgesic requirements were higher in Group A than in the other two groups (p < 0.05). Conclusion: A combination of 2% articaine and 0.75% ropivacaine for epidural anesthesia in a cesarean section should be preferred over epidural 0.75% ropivacaine alone. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

Dergi Adı REVISTA BRASILEIRA DE ANESTESIOLOGIA
Dergi Cilt Bilgisi 63
Dergi Sayısı 1
Sayfalar 85 - 98
Yayın Yılı 2013
Eser Adı
[dc.title]
Ropivacaine, Articaine or Combination of Ropivacaine and Articaine for Epidural Anesthesia in Cesarean Section: a Randomized, Prospective, Double-Blinded Study
Yazar
[dc.contributor.author]
Yurtlu, Derya Arslan
Yazar
[dc.contributor.author]
Kaya, Kadir
Yayın Yılı
[dc.date.issued]
2013
Yayıncı
[dc.publisher]
ELSEVIER SCIENCE INC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Background and objectives: Initiation of epidural anesthesia with long-lasting local anesthetics consumes a significant amount of time, which could be problematic in busy obstetric anesthesia suites. We have hypothesized that a combination of articaine and ropivacaine provides faster onset and even an early recovery of sensory-motor block characteristics. Methods: Sixty term parturients scheduled to have elective cesarean section were randomly allocated into three groups to receive either 20 mL 2% articaine (Group A), 10 mL 2% articaine + 10 mL 0.75% ropivacaine (Group AR) or 20 mL 0.75% ropivacaine (Group R) via lumbar epidural catheter. The onset time of sensory block to T-10, T-6 and maximum sensory block level, time to two segments regression from maximum sensory block level, onset time and duration of motor block were all recorded. Intraoperative and postoperative additional analgesic requirements were also recorded. Results: Demographic data were similar. The onset times of sensorial block to T-10 and T-6 were significantly shorter in Groups A and AR in comparison with Group R (p < 0.05). The onset times of motor block were similar in all groups, but a more intense motor block was observed in Group R (p < 0.05). Two segments regression time and motor block durations were significantly shorter in Groups A and AR in comparison with Group R (p < 0.05). Intraoperative supplementary analgesic requirements were higher in Group A than in the other two groups (p < 0.05). Conclusion: A combination of 2% articaine and 0.75% ropivacaine for epidural anesthesia in a cesarean section should be preferred over epidural 0.75% ropivacaine alone. (C) 2013 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.
Açıklama
[dc.description]
WOS: 000319781500007
Açıklama
[dc.description]
PubMed: 23438803
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Anesthesia, Epidural
Konu Başlıkları
[dc.subject]
Anesthetics
Konu Başlıkları
[dc.subject]
Local/ropivacaine
Konu Başlıkları
[dc.subject]
Carticaine
Konu Başlıkları
[dc.subject]
Cesarean Section
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0034-7094
ISSN
[dc.identifier.issn]
1806-907X
İlk Sayfa Sayısı
[dc.identifier.startpage]
85
Son Sayfa Sayısı
[dc.identifier.endpage]
98
Dergi Adı
[dc.relation.journal]
REVISTA BRASILEIRA DE ANESTESIOLOGIA
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
63
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/S0034-7094(13)70200-9
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3288
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
13
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 18:33
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Tıklayınız
ropivacaine articaine epidural anesthesia groups (Group sensory comparison Groups section cesarean requirements shorter significantly analgesic Intraoperative recorded similar regression segments maximum combination Demographic sensorial Background reserved rights Editora Elsevier Published Anestesiologia Brasileira Sociedade preferred should
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