Environmental boron exposure does not induce DNA damage in lymphocytes and buccal cells of females DNA damage in lymphocytes and buccal cells of boron exposed females
Boron (B) compounds are essential for plants and animals and beneficial for humans in nutritional amounts. I animals and humans increasing evidence have shown beneficial effects on B compounds on nutrition and on antioxidant status. The genotoxic effects of environmental B exposure in women living in boron-rich and boronpoor areas was examined in this study. For this purpose, the DNA damage in the lymphocytes and buccal cells of females were assessed by Comet and micronucleus (MN) assays respectively. No significant difference was observed in the DNA damage of the lymphocytes of B exposed groups of female volunteers in Comet assay. Even buccal micronucleus (MN) frequency observed in the high exposure group was significantly lower than the low exposure group (p < 0.05). The results of this study came to the same conclusions of the previous studies that boron does not induce DNA damage even under extreme exposure conditions.
| Yazar |
Basaran, Nursen Duydu, Yalcin Ustundag, Aylin Taner, Gokce Dilsiz, Sevtap Aydin Anlar, Hatice Gul Yalcin, Can Ozgur |
| Yayın Türü | Article |
| Tek Biçim Adres | https://hdl.handle.net/20.500.12628/2552 |
| Tek Biçim Adres | 10.1016/j.jtemb.2019.03.004 |
| Konu Başlıkları |
Boric acid
Boron exposure DNA damage |
| Koleksiyonlar |
Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD PubMed İndeksli Yayınlar Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu |
| Dergi Adı | JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY |
| Dergi Cilt Bilgisi | 53 |
| Sayfalar | 150 - 153 |
| Yayın Yılı | 2019 |
| Eser Adı [dc.title] | Environmental boron exposure does not induce DNA damage in lymphocytes and buccal cells of females DNA damage in lymphocytes and buccal cells of boron exposed females |
| Yazar [dc.contributor.author] | Basaran, Nursen |
| Yazar [dc.contributor.author] | Duydu, Yalcin |
| Yazar [dc.contributor.author] | Ustundag, Aylin |
| Yazar [dc.contributor.author] | Taner, Gokce |
| Yazar [dc.contributor.author] | Dilsiz, Sevtap Aydin |
| Yazar [dc.contributor.author] | Anlar, Hatice Gul |
| Yazar [dc.contributor.author] | Yalcin, Can Ozgur |
| Yayın Yılı [dc.date.issued] | 2019 |
| Yayıncı [dc.publisher] | ELSEVIER GMBH |
| Yayın Türü [dc.type] | article |
| Özet [dc.description.abstract] | Boron (B) compounds are essential for plants and animals and beneficial for humans in nutritional amounts. I animals and humans increasing evidence have shown beneficial effects on B compounds on nutrition and on antioxidant status. The genotoxic effects of environmental B exposure in women living in boron-rich and boronpoor areas was examined in this study. For this purpose, the DNA damage in the lymphocytes and buccal cells of females were assessed by Comet and micronucleus (MN) assays respectively. No significant difference was observed in the DNA damage of the lymphocytes of B exposed groups of female volunteers in Comet assay. Even buccal micronucleus (MN) frequency observed in the high exposure group was significantly lower than the low exposure group (p < 0.05). The results of this study came to the same conclusions of the previous studies that boron does not induce DNA damage even under extreme exposure conditions. |
| Açıklama [dc.description] | WOS: 000497982700024 |
| Açıklama [dc.description] | PubMed: 30910199 |
| Kayıt Giriş Tarihi [dc.date.accessioned] | 2019-12-23 |
| Açık Erişim Tarihi [dc.date.available] | 2019-12-23 |
| Yayın Dili [dc.language.iso] | eng |
| Konu Başlıkları [dc.subject] | Boric acid |
| Konu Başlıkları [dc.subject] | Boron exposure |
| Konu Başlıkları [dc.subject] | DNA damage |
| Haklar [dc.rights] | info:eu-repo/semantics/closedAccess |
| ISSN [dc.identifier.issn] | 0946-672X |
| Sponsor YAYINCI [dc.description.sponsorship] | Eti Mine Works General ManagementMinistry of Energy & Natural Resources - Turkey |
| Sponsor YAYINCI [dc.description.sponsorship] | The project was funded by Eti Mine Works General Management (2014-2017). |
| İlk Sayfa Sayısı [dc.identifier.startpage] | 150 |
| Son Sayfa Sayısı [dc.identifier.endpage] | 153 |
| Dergi Adı [dc.relation.journal] | JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY |
| Dergi Cilt Bilgisi [dc.identifier.volume] | 53 |
| Tek Biçim Adres [dc.identifier.uri] | https://dx.doi.org/10.1016/j.jtemb.2019.03.004 |
| Tek Biçim Adres [dc.identifier.uri] | https://hdl.handle.net/20.500.12628/2552 |
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