The association between serum vitamin B-12 deficiency and tension-type headache in Turkish children

This study aimed to determine the relationship between serum vitamin B12 level and tension-type headache. The study groups consisted of 75 patients (40 females, 35 males) with headache and a control group of 49 healthy children (25 females, 24 males). Serum vitamin B12 level < 200 pg/ml was defined as deficient, and < 160 pg/ml as severely deficient. The serum vitamin B12 level was measured by the electrochemiluminescence (ECLIA) method. The serum vitamin B12 levels in the headache and control groups were 273.01 +/- 76.77 and 316.22 +/- 74.53 pg/ml, with the difference determined as statistically significant (p = 0.003). In the case group, 18/75 patients (24%) had a serum vitamin B12 level below the normal of 200 pg/ml, and in the control group 4/49 (8%) patients were also below the normal range (p = 0.021). The serum vitamin B12 level in the children with tensiontype headache was significantly lower than that in the control group. Fromthe results of the study, itwas concluded that there may be an association between vitamin B12 level and tension-type headache. However, further clinical studies are needed.

Yazar Calik, Mustafa
Aktas, Mehmet Salih
Cecen, Emre
Piskin, Ibrahim Etem
Ayaydin, Hamza
Ornek, Zuhal
Karaca, Meryem
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3455
Tek Biçim Adres 10.1007/s10072-018-3286-5
Konu Başlıkları Vitamin B-12 deficiency
Headache
Depression
Anxiety
Children
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı NEUROLOGICAL SCIENCES
Dergi Cilt Bilgisi 39
Dergi Sayısı 6
Sayfalar 1009 - 1014
Yayın Yılı 2018
Eser Adı
[dc.title]
The association between serum vitamin B-12 deficiency and tension-type headache in Turkish children
Yazar
[dc.contributor.author]
Calik, Mustafa
Yazar
[dc.contributor.author]
Aktas, Mehmet Salih
Yazar
[dc.contributor.author]
Cecen, Emre
Yazar
[dc.contributor.author]
Piskin, Ibrahim Etem
Yazar
[dc.contributor.author]
Ayaydin, Hamza
Yazar
[dc.contributor.author]
Ornek, Zuhal
Yazar
[dc.contributor.author]
Karaca, Meryem
Yayın Yılı
[dc.date.issued]
2018
Yayıncı
[dc.publisher]
SPRINGER-VERLAG ITALIA SRL
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
This study aimed to determine the relationship between serum vitamin B12 level and tension-type headache. The study groups consisted of 75 patients (40 females, 35 males) with headache and a control group of 49 healthy children (25 females, 24 males). Serum vitamin B12 level < 200 pg/ml was defined as deficient, and < 160 pg/ml as severely deficient. The serum vitamin B12 level was measured by the electrochemiluminescence (ECLIA) method. The serum vitamin B12 levels in the headache and control groups were 273.01 +/- 76.77 and 316.22 +/- 74.53 pg/ml, with the difference determined as statistically significant (p = 0.003). In the case group, 18/75 patients (24%) had a serum vitamin B12 level below the normal of 200 pg/ml, and in the control group 4/49 (8%) patients were also below the normal range (p = 0.021). The serum vitamin B12 level in the children with tensiontype headache was significantly lower than that in the control group. Fromthe results of the study, itwas concluded that there may be an association between vitamin B12 level and tension-type headache. However, further clinical studies are needed.
Açıklama
[dc.description]
WOS: 000433091600004
Açıklama
[dc.description]
PubMed: 29520674
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Vitamin B-12 deficiency
Konu Başlıkları
[dc.subject]
Headache
Konu Başlıkları
[dc.subject]
Depression
Konu Başlıkları
[dc.subject]
Anxiety
Konu Başlıkları
[dc.subject]
Children
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1590-1874
ISSN
[dc.identifier.issn]
1590-3478
İlk Sayfa Sayısı
[dc.identifier.startpage]
1009
Son Sayfa Sayısı
[dc.identifier.endpage]
1014
Dergi Adı
[dc.relation.journal]
NEUROLOGICAL SCIENCES
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
39
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1007/s10072-018-3286-5
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3455
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
180
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
11 Haziran 2024 08:14
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Tıklayınız
vitamin headache control patients deficient normal children between groups males) females tension-type clinical studies needed tensiontype significantly Fromthe further However results association concluded significant defined healthy severely consisted relationship determine measured statistically determined difference levels
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