DECREASED HEART RATE VARIABILITY IN SICKLE CELL ANEMIA AS EFFECT OF PULMONARY ARTERIAL HYPERTENSION

Decreased heart rate variability (HRV) is associated with increased mortality risk in various diseases. The objective of this investigation: to study HRV in patients with sickle cell anemia (SCA) and to assess the effect of pulmonary arterial hypertension (PAH) on HRV in these patients. Materials and methods. HRV registration and Doppler echocardiographic assessment of systolic pulmonary arterial pressure (PAP) was carried out in 61 stable patients with SCA and 24 healthy subjects. Results. Low frequency power (LFP) and high frequency power (HFP) were decreased in SCA patients compared to healthy subjects. Among SCA patients, PAH patients had lower LFP and HFP than patients without PAH. In SCA patients, systolic PAP showed significant negative correlation with LFP and HFP. Conclusion. HRV is significantly decreased in SCA patients, especially in those with PAH. HRV may be particularly useful in early detection of PAH patients who may have worse prognosis and higher mortality risk.

Yazar Akgul, F.
Batyraliev, T. A.
Fettser, D., V
Seyfeli, E.
Arystan, A. G.
Seydaliyeva, T.
Gali, E.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2342
Tek Biçim Adres 10.18087/cardio.2019.4.10237
Konu Başlıkları Sickle cell anemia
pulmonary hypertension
heart rate variability
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı KARDIOLOGIYA
Dergi Cilt Bilgisi 59
Dergi Sayısı 4
Sayfalar 39 - 44
Yayın Yılı 2019
Eser Adı
[dc.title]
DECREASED HEART RATE VARIABILITY IN SICKLE CELL ANEMIA AS EFFECT OF PULMONARY ARTERIAL HYPERTENSION
Yazar
[dc.contributor.author]
Akgul, F.
Yazar
[dc.contributor.author]
Batyraliev, T. A.
Yazar
[dc.contributor.author]
Fettser, D., V
Yazar
[dc.contributor.author]
Seyfeli, E.
Yazar
[dc.contributor.author]
Arystan, A. G.
Yazar
[dc.contributor.author]
Seydaliyeva, T.
Yazar
[dc.contributor.author]
Gali, E.
Yayın Yılı
[dc.date.issued]
2019
Yayıncı
[dc.publisher]
RUSSIAN HEART FAILURE SOC
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Decreased heart rate variability (HRV) is associated with increased mortality risk in various diseases. The objective of this investigation: to study HRV in patients with sickle cell anemia (SCA) and to assess the effect of pulmonary arterial hypertension (PAH) on HRV in these patients. Materials and methods. HRV registration and Doppler echocardiographic assessment of systolic pulmonary arterial pressure (PAP) was carried out in 61 stable patients with SCA and 24 healthy subjects. Results. Low frequency power (LFP) and high frequency power (HFP) were decreased in SCA patients compared to healthy subjects. Among SCA patients, PAH patients had lower LFP and HFP than patients without PAH. In SCA patients, systolic PAP showed significant negative correlation with LFP and HFP. Conclusion. HRV is significantly decreased in SCA patients, especially in those with PAH. HRV may be particularly useful in early detection of PAH patients who may have worse prognosis and higher mortality risk.
Açıklama
[dc.description]
WOS: 000474853700006
Açıklama
[dc.description]
PubMed: 31002038
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
rus
Konu Başlıkları
[dc.subject]
Sickle cell anemia
Konu Başlıkları
[dc.subject]
pulmonary hypertension
Konu Başlıkları
[dc.subject]
heart rate variability
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0022-9040
İlk Sayfa Sayısı
[dc.identifier.startpage]
39
Son Sayfa Sayısı
[dc.identifier.endpage]
44
Dergi Adı
[dc.relation.journal]
KARDIOLOGIYA
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
59
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.18087/cardio.2019.4.10237
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2342
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
20
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Şubat 2024 07:27
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Tıklayınız
patients decreased systolic arterial frequency pulmonary healthy subjects mortality compared prognosis higher detection particularly especially significantly Conclusion correlation negative significant showed useful without Decreased carried Results objective anemia sickle investigation diseases various increased associated variability
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