The oncocytic variant of papillary thyroid carcinoma with multifocal involvement: A case report

The oncocytic variant of papillary thyroid carcinoma is an uncommon form of neoplasm, the clinicopathological features and biological behavior of which have not been precisely defined. The pattern of multifocal growth is an uncommon feature. The case was a 64-year-old female patient with multinodular goiter who had undergone total thyroidectomy. Microscopic examination of cross-sections of the multiple nodules revealed a tumoral lesion characterized by a predominant follicular growth pattern, and sparse, small, abortive papillary structures. Most of the tumor cells also displayed the classical nuclear features of papillary carcinoma, like optically clear nuclei, overlapping of the nuclei, irregular nuclear membranes, and sparse nucleoli. Prominent nuclear grooves and intranuclear pseudoinclusions were seen in many of the neoplastic cells. Due to the presence of the characteristic nuclear features, the diagnosis was papillary carcinoma. The oncocytic variant of papillary carcinoma, although rare, appears to represent a morphologically distinctive variant of papillary cancer. © 2010 Onkoloji Dernegi - © 2010 Association of Oncology.

Dergi Adı Turk Onkoloji Dergisi
Dergi Cilt Bilgisi 25
Dergi Sayısı 4
Sayfalar 161 - 164
Yayın Yılı 2010
Eser Adı
[dc.title]
The oncocytic variant of papillary thyroid carcinoma with multifocal involvement: A case report
Yazar
[dc.contributor.author]
Barut F.
Yazar
[dc.contributor.author]
Özdamar Ş.O.
Yazar
[dc.contributor.author]
Bektaş S.
Yazar
[dc.contributor.author]
Taşcilar Ö.
Yazar
[dc.contributor.author]
Dogan Gün B.
Yayın Yılı
[dc.date.issued]
2010
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The oncocytic variant of papillary thyroid carcinoma is an uncommon form of neoplasm, the clinicopathological features and biological behavior of which have not been precisely defined. The pattern of multifocal growth is an uncommon feature. The case was a 64-year-old female patient with multinodular goiter who had undergone total thyroidectomy. Microscopic examination of cross-sections of the multiple nodules revealed a tumoral lesion characterized by a predominant follicular growth pattern, and sparse, small, abortive papillary structures. Most of the tumor cells also displayed the classical nuclear features of papillary carcinoma, like optically clear nuclei, overlapping of the nuclei, irregular nuclear membranes, and sparse nucleoli. Prominent nuclear grooves and intranuclear pseudoinclusions were seen in many of the neoplastic cells. Due to the presence of the characteristic nuclear features, the diagnosis was papillary carcinoma. The oncocytic variant of papillary carcinoma, although rare, appears to represent a morphologically distinctive variant of papillary cancer. © 2010 Onkoloji Dernegi - © 2010 Association of Oncology.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Multifocal pattern
Konu Başlıkları
[dc.subject]
Oncocytic variant
Konu Başlıkları
[dc.subject]
Papillary thyroid carcinoma
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1300-7467
İlk Sayfa Sayısı
[dc.identifier.startpage]
161
Son Sayfa Sayısı
[dc.identifier.endpage]
164
Dergi Adı
[dc.relation.journal]
Turk Onkoloji Dergisi
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
25
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/8171
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
38
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
20 Şubat 2024 06:25
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Tıklayınız
papillary carcinoma nuclear variant features pattern growth oncocytic nuclei sparse uncommon intranuclear grooves displayed Prominent nucleoli membranes optically classical irregular overlapping pseudoinclusions diagnosis morphologically Oncology Association Dernegi Onkoloji cancer distinctive represent appears although characteristic presence
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