A case of langerhans cell histiocytosis with multisystemic involvement in an adult patient

Langerhans cell histiocytosis (LCH) is a rare group of idiopathic diseases characterized by abnormal proliferation of bone marrow-derived dendritic cells called histiocytes. It is more common in childhood, but in the literature, some adult cases have been reported. For several reasons, the disease is more familiar to pediatricians than it is to physicians handling adult cases; therefore, the diagnosis of adult cases is often delayed or missed. The clinical course of LCH is variable, ranging from a self-healing solitary bone lesion to a widely disseminated life-threatening disease. The diagnosis of LCH should be based on histologic and immunophenotypic examination of perilesional skin. In this report, we present a case of LCH in a 66-yearold woman with bone, skin, and pituitary gland involvement; this case emphasizes that a patient with LCH should undergo careful multidisciplinary evaluation. © 2016 by Erciyes University School of Medicine.

Dergi Adı Erciyes Tip Dergisi
Dergi Cilt Bilgisi 38
Dergi Sayısı 2
Sayfalar 78 - 80
Yayın Yılı 2016
Eser Adı
[dc.title]
A case of langerhans cell histiocytosis with multisystemic involvement in an adult patient
Yazar
[dc.contributor.author]
Demirel B.G.
Yazar
[dc.contributor.author]
Tekin N.S.
Yazar
[dc.contributor.author]
Barut F.
Yazar
[dc.contributor.author]
Aslaner M.
Yazar
[dc.contributor.author]
Koca R.
Yazar
[dc.contributor.author]
Gencer D.
Yayın Yılı
[dc.date.issued]
2016
Yayıncı
[dc.publisher]
AVES Ibrahim Kara
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Langerhans cell histiocytosis (LCH) is a rare group of idiopathic diseases characterized by abnormal proliferation of bone marrow-derived dendritic cells called histiocytes. It is more common in childhood, but in the literature, some adult cases have been reported. For several reasons, the disease is more familiar to pediatricians than it is to physicians handling adult cases; therefore, the diagnosis of adult cases is often delayed or missed. The clinical course of LCH is variable, ranging from a self-healing solitary bone lesion to a widely disseminated life-threatening disease. The diagnosis of LCH should be based on histologic and immunophenotypic examination of perilesional skin. In this report, we present a case of LCH in a 66-yearold woman with bone, skin, and pituitary gland involvement; this case emphasizes that a patient with LCH should undergo careful multidisciplinary evaluation. © 2016 by Erciyes University School of Medicine.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Adult
Konu Başlıkları
[dc.subject]
Dendritic cells
Konu Başlıkları
[dc.subject]
Langerhans cell histiocytosis
Konu Başlıkları
[dc.subject]
Multidisciplinary
Konu Başlıkları
[dc.subject]
Multisystemic
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1300199X
İlk Sayfa Sayısı
[dc.identifier.startpage]
78
Son Sayfa Sayısı
[dc.identifier.endpage]
80
Dergi Adı
[dc.relation.journal]
Erciyes Tip Dergisi
Dergi Sayısı
[dc.identifier.issue]
2
Dergi Cilt Bilgisi
[dc.identifier.volume]
38
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.5152/etd.2016.150038
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3874
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
428
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
16 Temmuz 2024 20:19
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Tıklayınız
diagnosis disease should perilesional Langerhans examination immunophenotypic histologic life-threatening disseminated widely lesion 66-yearold report careful Medicine School University Erciyes evaluation multidisciplinary undergo patient emphasizes involvement pituitary self-healing present solitary marrow-derived childhood common histiocytes called dendritic
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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