Primary intestinal diffuse large B-cell lymphoma forming multiple lymphomatous polyposis

Multifocal and skip involvement is quite a rare developmental pattern for primary gastrointestinal lymphomas. A 25-year-old male patient with diffuse large B-cell lymphoma of the small intestine, with macroscopic features and clinical aspects imitating Crohn's disease and attracting attention with cobblestone-like appearance, is presented herein together with the clinical and pathological features. Multiple ulcerated lesions were also observed infiltrating the serosa with polypoid appearance, 2.5 cm in largest diameter, within the resected jejunoileal specimen, which displayed patchy, healthy-appearing mucosal areas. In microscopic examination, a tumoral infiltration was observed comprised of pleomorphic, atypical lymphoid cells with abundant eosinophilic cytoplasm, marked nucleoli and vesicular nuclei. A B-cell phenotype immunoreaction was observed by vimentin, LCA, CD20, and CD79a in those atypical cells. The diagnosis of the case was diffuse large B-cell lymphoma.The possibility of the presence of this disorder, although rare, is emphasized here for patients applying to the hospital with the signs and symptoms of Crohn's disease.

Dergi Adı Turkish Journal of Gastroenterology
Dergi Cilt Bilgisi 22
Dergi Sayısı 3
Sayfalar 324 - 328
Yayın Yılı 2011
Eser Adı
[dc.title]
Primary intestinal diffuse large B-cell lymphoma forming multiple lymphomatous polyposis
Yazar
[dc.contributor.author]
Barut F.
Yazar
[dc.contributor.author]
Onak Kandemir N.
Yazar
[dc.contributor.author]
Karakaya K.
Yazar
[dc.contributor.author]
Kökten N.
Yazar
[dc.contributor.author]
Özdamar Ş.O.
Yayın Yılı
[dc.date.issued]
2011
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Multifocal and skip involvement is quite a rare developmental pattern for primary gastrointestinal lymphomas. A 25-year-old male patient with diffuse large B-cell lymphoma of the small intestine, with macroscopic features and clinical aspects imitating Crohn's disease and attracting attention with cobblestone-like appearance, is presented herein together with the clinical and pathological features. Multiple ulcerated lesions were also observed infiltrating the serosa with polypoid appearance, 2.5 cm in largest diameter, within the resected jejunoileal specimen, which displayed patchy, healthy-appearing mucosal areas. In microscopic examination, a tumoral infiltration was observed comprised of pleomorphic, atypical lymphoid cells with abundant eosinophilic cytoplasm, marked nucleoli and vesicular nuclei. A B-cell phenotype immunoreaction was observed by vimentin, LCA, CD20, and CD79a in those atypical cells. The diagnosis of the case was diffuse large B-cell lymphoma.The possibility of the presence of this disorder, although rare, is emphasized here for patients applying to the hospital with the signs and symptoms of Crohn's disease.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Diffuse large B-cell lymphoma
Konu Başlıkları
[dc.subject]
Intestinal involvement
Konu Başlıkları
[dc.subject]
Multiple lymphomatous polyposis
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1300-4948
İlk Sayfa Sayısı
[dc.identifier.startpage]
324
Son Sayfa Sayısı
[dc.identifier.endpage]
328
Dergi Adı
[dc.relation.journal]
Turkish Journal of Gastroenterology
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
22
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.4318/tjg.2011.0220
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7176
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
50
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
30 Mart 2024 13:48
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Tıklayınız
B-cell observed features lymphoma clinical disease appearance atypical diffuse nucleoli marked cytoplasm eosinophilic abundant lymphoid hospital nuclei pleomorphic comprised symptoms infiltration tumoral examination microscopic vesicular immunoreaction phenotype patients disorder although presence possibility emphasized diagnosis mucosal
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