Experience with the Edwards MIRA mechanical bileaflet valve: In the aortic and mitral positions

The Edwards MIRA bileaflet mechanical prosthesis, a heart valve not yet available in the United States, is designed with a unique hinge mechanism, curved leaflets, and thin titanium housing. We performed this study to investigate its clinical performance and postoperative hemodynamic results. We implanted 58 Edwards MIRA prostheses in 51 patients in the aortic (n=18), mitral (n=26), and aortic and mitral (n=7) positions. Patients' ages ranged from 25 to 84 years (mean age, 53.7 ± 13.6). Operative mortality was 2% (n=1), and late mortality was 4% (n=2). Thromboembolic events were observed in 2 patients (valve thrombosis in 1 and a cerebrovascular event in 1). There were no complications related to anticoagulation. No signs of valvular dysfunction or paravalvular leakage were observed. Peak transvalvular gradients of the aortic prostheses ranged from 24.25 ± 5.32 mmHg for the 21-mm valve to 11 ± 1.41 mmHg for the 25-mm valve. The effective orifice area ranged from 1.99 ± 0.12 cm2 for the 21-mm valve to 2.44 ± 0.17 cm2 for the 25-mm valve. The mean transvalvular gradients of the mitral prostheses ranged from 5.85 ± 2.91 mmHg for the 27-mm valve to 4.5 ± 0 mmHg for the 31-mm valve. The effective orifice area ranged from 2.31 ± 0.03 cm2 for the 27-mm valve to 2.64 ± 0.05 cm2 for the 33-mm valve. These preliminary data suggest good hemodynamic function and a low rate of valve-related complications in the use of the Edwards MIRA mechanical prosthesis. © 2006 by the Texas Heart® Institute.

Dergi Adı Texas Heart Institute Journal
Dergi Cilt Bilgisi 33
Dergi Sayısı 3
Sayfalar 328 - 332
Yayın Yılı 2006
Eser Adı
[dc.title]
Experience with the Edwards MIRA mechanical bileaflet valve: In the aortic and mitral positions
Yazar
[dc.contributor.author]
Kale A.
Yazar
[dc.contributor.author]
Yildiz U.
Yazar
[dc.contributor.author]
Can B.
Yazar
[dc.contributor.author]
Kandemir O.
Yazar
[dc.contributor.author]
Tokmakoglu H.
Yazar
[dc.contributor.author]
Tezcaner T.
Yazar
[dc.contributor.author]
Zorlutuna, Yaman
Yayın Yılı
[dc.date.issued]
2006
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
The Edwards MIRA bileaflet mechanical prosthesis, a heart valve not yet available in the United States, is designed with a unique hinge mechanism, curved leaflets, and thin titanium housing. We performed this study to investigate its clinical performance and postoperative hemodynamic results. We implanted 58 Edwards MIRA prostheses in 51 patients in the aortic (n=18), mitral (n=26), and aortic and mitral (n=7) positions. Patients' ages ranged from 25 to 84 years (mean age, 53.7 ± 13.6). Operative mortality was 2% (n=1), and late mortality was 4% (n=2). Thromboembolic events were observed in 2 patients (valve thrombosis in 1 and a cerebrovascular event in 1). There were no complications related to anticoagulation. No signs of valvular dysfunction or paravalvular leakage were observed. Peak transvalvular gradients of the aortic prostheses ranged from 24.25 ± 5.32 mmHg for the 21-mm valve to 11 ± 1.41 mmHg for the 25-mm valve. The effective orifice area ranged from 1.99 ± 0.12 cm2 for the 21-mm valve to 2.44 ± 0.17 cm2 for the 25-mm valve. The mean transvalvular gradients of the mitral prostheses ranged from 5.85 ± 2.91 mmHg for the 27-mm valve to 4.5 ± 0 mmHg for the 31-mm valve. The effective orifice area ranged from 2.31 ± 0.03 cm2 for the 27-mm valve to 2.64 ± 0.05 cm2 for the 33-mm valve. These preliminary data suggest good hemodynamic function and a low rate of valve-related complications in the use of the Edwards MIRA mechanical prosthesis. © 2006 by the Texas Heart® Institute.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Aortic valve/surgery
Konu Başlıkları
[dc.subject]
Cerebrovascular disorders/etiology
Konu Başlıkları
[dc.subject]
Embolism
Konu Başlıkları
[dc.subject]
Heart valve diseases/surgery
Konu Başlıkları
[dc.subject]
Heart valve prosthesis
Konu Başlıkları
[dc.subject]
Mitral valve/surgery
Konu Başlıkları
[dc.subject]
Postoperative complications
Konu Başlıkları
[dc.subject]
Prosthesis design
Konu Başlıkları
[dc.subject]
Prosthesis failure
Konu Başlıkları
[dc.subject]
Thrombosis
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0730-2347
İlk Sayfa Sayısı
[dc.identifier.startpage]
328
Son Sayfa Sayısı
[dc.identifier.endpage]
332
Dergi Adı
[dc.relation.journal]
Texas Heart Institute Journal
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
33
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/5816
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
12
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
03 Şubat 2024 15:45
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Tıklayınız
ranged Edwards mitral aortic prostheses gradients prosthesis transvalvular patients mortality complications hemodynamic orifice observed mechanical effective preliminary leakage Heart® paravalvular dysfunction valvular Institute anticoagulation suggest function valve-related related curved postoperative performance clinical investigate performed housing
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