Pseudocholinesterase levels in patients under electroconvulsive therapy

Objectives: In this study, we aimed to retrospectively assess the correlation of pseudocholinesterase (PChE) levels with age, gender, body weight and diagnosed psychiatric diseases in electroconvulsive therapy (ECT) cases. Methods: This retrospective study was conducted at Bülent Ecevit University Hospital, Zonguldak, Turkey, between 2007 and 2011. In the study, 193 ECT case files were retrospectively scanned to evaluate PChE values before ECT and other file information. Results: There was no difference between gender in terms of PChE levels. Correlation analysis determined a weakly positive correlation between age (p=0.013; correlation coefficient [cc]: 0.178) and body weight (p<0.001; cc: 0.273) and PChE levels. No correlation was found between age, gender, weight or psychiatric diagnosis, and PChE levels. Conclusion: Neuromuscular blockage is a significant factor that increases patient safety, while increasing the efficacy of ECT. In choosing muscle relaxant agents, both patient factors and the pharmacological properties of the neuromuscular blocker should be considered. We think that in situations with delayed recovery of ECT cases without identified PChE levels, low PChE levels must be considered. © 2018, Saudi Arabian Armed Forces Hospital. All rights reserved.

Yazar Küçükosman G.
Pişkin Ö.
Hancı V.
Okyay R.D.
Ayoğlu H.
Yurtlu B.S.
Akın M.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7249
Tek Biçim Adres 10.15537/smj.2018.1.21307
Konu Başlıkları Electroconvulsive therapy
Pseudocholinesterase levels
Retrospective study
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
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Dergi Adı Saudi Medical Journal
Dergi Cilt Bilgisi 39
Dergi Sayısı 1
Sayfalar 103 - 106
Yayın Yılı 2018
Eser Adı
[dc.title]
Pseudocholinesterase levels in patients under electroconvulsive therapy
Yazar
[dc.contributor.author]
Küçükosman G.
Yazar
[dc.contributor.author]
Pişkin Ö.
Yazar
[dc.contributor.author]
Hancı V.
Yazar
[dc.contributor.author]
Okyay R.D.
Yazar
[dc.contributor.author]
Ayoğlu H.
Yazar
[dc.contributor.author]
Yurtlu B.S.
Yazar
[dc.contributor.author]
Akın M.
Yayın Yılı
[dc.date.issued]
2018
Yayıncı
[dc.publisher]
Saudi Arabian Armed Forces Hospital
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objectives: In this study, we aimed to retrospectively assess the correlation of pseudocholinesterase (PChE) levels with age, gender, body weight and diagnosed psychiatric diseases in electroconvulsive therapy (ECT) cases. Methods: This retrospective study was conducted at Bülent Ecevit University Hospital, Zonguldak, Turkey, between 2007 and 2011. In the study, 193 ECT case files were retrospectively scanned to evaluate PChE values before ECT and other file information. Results: There was no difference between gender in terms of PChE levels. Correlation analysis determined a weakly positive correlation between age (p=0.013; correlation coefficient [cc]: 0.178) and body weight (p<0.001; cc: 0.273) and PChE levels. No correlation was found between age, gender, weight or psychiatric diagnosis, and PChE levels. Conclusion: Neuromuscular blockage is a significant factor that increases patient safety, while increasing the efficacy of ECT. In choosing muscle relaxant agents, both patient factors and the pharmacological properties of the neuromuscular blocker should be considered. We think that in situations with delayed recovery of ECT cases without identified PChE levels, low PChE levels must be considered. © 2018, Saudi Arabian Armed Forces Hospital. All rights reserved.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Electroconvulsive therapy
Konu Başlıkları
[dc.subject]
Pseudocholinesterase levels
Konu Başlıkları
[dc.subject]
Retrospective study
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0379-5284
İlk Sayfa Sayısı
[dc.identifier.startpage]
103
Son Sayfa Sayısı
[dc.identifier.endpage]
106
Dergi Adı
[dc.relation.journal]
Saudi Medical Journal
Dergi Sayısı
[dc.identifier.issue]
1
Dergi Cilt Bilgisi
[dc.identifier.volume]
39
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.15537/smj.2018.1.21307
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7249
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
412
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
06 Eylül 2024 19:15
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levels between correlation gender weight psychiatric Hospital considered patient retrospectively efficacy choosing muscle increasing safety blockage increases factor significant agents Neuromuscular Conclusion diagnosis relaxant Objectives identified reserved rights Forces Arabian without factors recovery delayed situations
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