Evaluation of cardiac functions by tissue Doppler echocardiography in the long term follow-up of patients with childhood Hodgkin Lymphoma

Aim: Treatment-associated cardiomyopathy which is one of the side effects of treatment, can be asymptomatic in Hodgkin lymphoma patients. The aim of this study was to find out whether tissue Doppler echocardiography was superior to conventional echocardiography in determining potential cardiac problems in the patients diagnosed with Hodgkin lymphoma. Material and Method: A total of 17 Hodgkin lymphoma patients (12 males, 5 females), and whose treatment had been stopped for at least 4 years were being followed-up with disease-free status and without cardiac symptoms and a control group of 14 healthy persons (8 males, 6 females) were included in the study. The cardiac functions of the patients were evaluated by M-mode, 2 dimentional, colour Doppler, CW Doppler and pulse Doppler techniques. Data analyzes were evaluated by program of Statistical Package for Social Science for Windows 11.5, and Shapiro Wilk, Student's t testi, Mann Whitney U, Fisher's exact chi square tests, respectively. Hospital ethic committee consent was received for the study (07.05.2007/no:5639). Results: There were no statistical differences between the two groups (p=0.302 and p=0.860 respectively) when both groups were evaluated in terms of ejection fraction and fraction shortening by conventional echocardiography technique. Evaluation of both groups for the left ventricle isovolumic contraction time revealed a statistically significant longer time in the patient group compared with the control group (p: 0.038). The results were found longer in the patient group compared with the control group when both groups were evaluated in terms of myocardial performance index parameters and the left ventricle isovolumic contraction time parameters (p=0.029 and p=0.049, respectively). Conclusions: We concluded that the left ventricle isovolumic contraction time, the left ventricle isovolumic acceleration time and myocardial performance index tests are important parameters for the early detection of cardiac pathologies that may develop in relation to chemotherapy. (Turk Arch Ped 2011; 46:228-33)

Yazar Bozkurt, Ceyhun
Orun, Utku Arman
Ertem, Ayse Ulya
Ocal, Burhan
Sahin, Gurses
Yuksek, Nazmiye
Ozdemir, Sonay Incesoy
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/2581
Tek Biçim Adres 10.4274/tpa.46.79
Konu Başlıkları Anthracycline
cardiotoxicity
Hodgkin lymphoma
side effect
tissue Doppler echocardiography
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
Dergi Cilt Bilgisi 46
Dergi Sayısı 3
Sayfalar 228 - 233
Yayın Yılı 2011
Eser Adı
[dc.title]
Evaluation of cardiac functions by tissue Doppler echocardiography in the long term follow-up of patients with childhood Hodgkin Lymphoma
Yazar
[dc.contributor.author]
Bozkurt, Ceyhun
Yazar
[dc.contributor.author]
Orun, Utku Arman
Yazar
[dc.contributor.author]
Ertem, Ayse Ulya
Yazar
[dc.contributor.author]
Ocal, Burhan
Yazar
[dc.contributor.author]
Sahin, Gurses
Yazar
[dc.contributor.author]
Yuksek, Nazmiye
Yazar
[dc.contributor.author]
Ozdemir, Sonay Incesoy
Yayın Yılı
[dc.date.issued]
2011
Yayıncı
[dc.publisher]
GALENOS YAYINCILIK
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Aim: Treatment-associated cardiomyopathy which is one of the side effects of treatment, can be asymptomatic in Hodgkin lymphoma patients. The aim of this study was to find out whether tissue Doppler echocardiography was superior to conventional echocardiography in determining potential cardiac problems in the patients diagnosed with Hodgkin lymphoma. Material and Method: A total of 17 Hodgkin lymphoma patients (12 males, 5 females), and whose treatment had been stopped for at least 4 years were being followed-up with disease-free status and without cardiac symptoms and a control group of 14 healthy persons (8 males, 6 females) were included in the study. The cardiac functions of the patients were evaluated by M-mode, 2 dimentional, colour Doppler, CW Doppler and pulse Doppler techniques. Data analyzes were evaluated by program of Statistical Package for Social Science for Windows 11.5, and Shapiro Wilk, Student's t testi, Mann Whitney U, Fisher's exact chi square tests, respectively. Hospital ethic committee consent was received for the study (07.05.2007/no:5639). Results: There were no statistical differences between the two groups (p=0.302 and p=0.860 respectively) when both groups were evaluated in terms of ejection fraction and fraction shortening by conventional echocardiography technique. Evaluation of both groups for the left ventricle isovolumic contraction time revealed a statistically significant longer time in the patient group compared with the control group (p: 0.038). The results were found longer in the patient group compared with the control group when both groups were evaluated in terms of myocardial performance index parameters and the left ventricle isovolumic contraction time parameters (p=0.029 and p=0.049, respectively). Conclusions: We concluded that the left ventricle isovolumic contraction time, the left ventricle isovolumic acceleration time and myocardial performance index tests are important parameters for the early detection of cardiac pathologies that may develop in relation to chemotherapy. (Turk Arch Ped 2011; 46:228-33)
Açıklama
[dc.description]
WOS: 000294753600009
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
tur
Konu Başlıkları
[dc.subject]
Anthracycline
Konu Başlıkları
[dc.subject]
cardiotoxicity
Konu Başlıkları
[dc.subject]
Hodgkin lymphoma
Konu Başlıkları
[dc.subject]
side effect
Konu Başlıkları
[dc.subject]
tissue Doppler echocardiography
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1306-0015
İlk Sayfa Sayısı
[dc.identifier.startpage]
228
Son Sayfa Sayısı
[dc.identifier.endpage]
233
Dergi Adı
[dc.relation.journal]
TURK PEDIATRI ARSIVI-TURKISH ARCHIVES OF PEDIATRICS
Dergi Sayısı
[dc.identifier.issue]
3
Dergi Cilt Bilgisi
[dc.identifier.volume]
46
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.4274/tpa.46.79
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/2581
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
193
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
11 Haziran 2024 01:15
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Tıklayınız
ventricle patients Doppler evaluated cardiac groups isovolumic echocardiography control Hodgkin lymphoma parameters contraction longer patient females) fraction respectively) compared treatment conventional myocardial performance between differences statistical respectively Hospital Results chemotherapy 2007/no received consent committee results
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