The effect of Helicobacter pylori on insulin resistance

Helicobacter pylori causes a lifelong infection in the stomach after exposure. H. pylorihas been shown to be associated with peptic ulcer and gastric cancer development. Moreover, it is held responsible for some other nongastric diseases. Among them, coronary heart disease attracts much debate. Many studies have demonstrated a close relationship between insulin resistance and atherosclerosis. Chronic inflammation and alterations in counter-regulatory hormones are deemed responsible for the etiology of insulin resistance. We aimed to examine the effect of H. pylori on insulin resistance. Sixty-three patients were enrolled in the study. Patients were divided into two groups according to H. pylori presence. HOMA-IR (homeostasis model assessment of insulin resistance) level was used to assess insülin resistance. Thirty-six patients were H. pylori positive and 27 were H. pylori negative. There was no difference between the two groups with regard to age, gender, or body mass index. HOMA-IR level was 1.73± 1.1 in the H. pylori-negative group, whereas it was 2.56 ± 1.54 in the H. pylori-positive group (P < 0.05). This study provides the first direct evidence for an association between chronic H. pylori infection and insulin resistance. © 2005 Springer Science + Business Media, Inc.

Yazar Aydemir S.
Bayraktaroglu T.
Sert M.
Sokmen C.
Atmaca H.
Mungan G.
Gun B.D.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7942
Tek Biçim Adres 10.1007/s10620-005-3012-z
Konu Başlıkları Helicobacter pylori
Insulin resistance
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Digestive Diseases and Sciences
Dergi Cilt Bilgisi 50
Dergi Sayısı 11
Sayfalar 2090 - 2093
Yayın Yılı 2005
Eser Adı
[dc.title]
The effect of Helicobacter pylori on insulin resistance
Yazar
[dc.contributor.author]
Aydemir S.
Yazar
[dc.contributor.author]
Bayraktaroglu T.
Yazar
[dc.contributor.author]
Sert M.
Yazar
[dc.contributor.author]
Sokmen C.
Yazar
[dc.contributor.author]
Atmaca H.
Yazar
[dc.contributor.author]
Mungan G.
Yazar
[dc.contributor.author]
Gun B.D.
Yayın Yılı
[dc.date.issued]
2005
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Helicobacter pylori causes a lifelong infection in the stomach after exposure. H. pylorihas been shown to be associated with peptic ulcer and gastric cancer development. Moreover, it is held responsible for some other nongastric diseases. Among them, coronary heart disease attracts much debate. Many studies have demonstrated a close relationship between insulin resistance and atherosclerosis. Chronic inflammation and alterations in counter-regulatory hormones are deemed responsible for the etiology of insulin resistance. We aimed to examine the effect of H. pylori on insulin resistance. Sixty-three patients were enrolled in the study. Patients were divided into two groups according to H. pylori presence. HOMA-IR (homeostasis model assessment of insulin resistance) level was used to assess insülin resistance. Thirty-six patients were H. pylori positive and 27 were H. pylori negative. There was no difference between the two groups with regard to age, gender, or body mass index. HOMA-IR level was 1.73± 1.1 in the H. pylori-negative group, whereas it was 2.56 ± 1.54 in the H. pylori-positive group (P < 0.05). This study provides the first direct evidence for an association between chronic H. pylori infection and insulin resistance. © 2005 Springer Science + Business Media, Inc.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Helicobacter pylori
Konu Başlıkları
[dc.subject]
Insulin resistance
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0163-2116
İlk Sayfa Sayısı
[dc.identifier.startpage]
2090
Son Sayfa Sayısı
[dc.identifier.endpage]
2093
Dergi Adı
[dc.relation.journal]
Digestive Diseases and Sciences
Dergi Sayısı
[dc.identifier.issue]
11
Dergi Cilt Bilgisi
[dc.identifier.volume]
50
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1007/s10620-005-3012-z
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7942
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
14
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 18:55
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Tıklayınız
pylori resistance insulin between responsible groups patients HOMA-IR infection (homeostasis regard difference negative resistance) positive Thirty-six assessment insülin assess gender Helicobacter Business Science Springer chronic association evidence direct provides pylori-positive presence pylori-negative whereas according gastric
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