Pretreatment Neutrophil-Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy

Objective To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low- from high-grade parotid gland tumors. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Results Mean neutrophil percentage (63.50% ± 12.11% vs 58.76% ± 8.20%, P =.008) and NLR (3.29 ± 3.13 vs 2.13 ± 1.26, P =.008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42 ± 0.72 103/mm3 vs 1.97 ± 0.87 103/mm3, P <.001) and percentage (30.67% ± 7.68% vs 26.86% ± 10.15%, P =.011) were lower in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte percentage and NLR were significantly different between low- and high-grade malignant parotid gland tumors (P =.026 and P =.030, respectively). Conclusion Elevated NLR could be an inflammatory marker to distinguish low- from high-grade malignant parotid gland tumors. © Official journal of the American Academy of Otolaryngology-Head and Neck Surgery Foundation.

Yazar Damar M.
Dinç A.E.
Erdem D.
Aydil U.
Kizil Y.
Eravcl F.C.
Biskin S.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7153
Tek Biçim Adres 10.1177/0194599816659257
Konu Başlıkları high-grade malignant tumor
inflammatory marker
neutrophil-lymphocyte ratio
salivary gland tumors
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
Dergi Adı Otolaryngology - Head and Neck Surgery (United States)
Dergi Cilt Bilgisi 155
Dergi Sayısı 6
Sayfalar 988 - 996
Yayın Yılı 2016
Eser Adı
[dc.title]
Pretreatment Neutrophil-Lymphocyte Ratio in Salivary Gland Tumors Is Associated with Malignancy
Yazar
[dc.contributor.author]
Damar M.
Yazar
[dc.contributor.author]
Dinç A.E.
Yazar
[dc.contributor.author]
Erdem D.
Yazar
[dc.contributor.author]
Aydil U.
Yazar
[dc.contributor.author]
Kizil Y.
Yazar
[dc.contributor.author]
Eravcl F.C.
Yazar
[dc.contributor.author]
Biskin S.
Yayın Yılı
[dc.date.issued]
2016
Yayıncı
[dc.publisher]
SAGE Publications Inc.
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective To assess pretreatment levels in the counts and percentages of leukocytes and the neutrophil-lymphocyte ratio (NLR) in benign and malignant salivary gland tumors (SGTs) while investigating whether NLR is an inflammatory marker for distinguishing low- from high-grade parotid gland tumors. Study Design Case series with chart review. Setting Tertiary referral center. Subjects and Methods This study was performed on 182 patients with SGTs (age range: 16-87 years; 93 male and 89 female) who were treated between January 2010 and May 2015. Pretreatment counts and percentages of leukocytes and NLR were measured preoperatively in benign and malignant tumors. Results Mean neutrophil percentage (63.50% ± 12.11% vs 58.76% ± 8.20%, P =.008) and NLR (3.29 ± 3.13 vs 2.13 ± 1.26, P =.008) were significantly higher in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte count (2.42 ± 0.72 103/mm3 vs 1.97 ± 0.87 103/mm3, P <.001) and percentage (30.67% ± 7.68% vs 26.86% ± 10.15%, P =.011) were lower in patients with malignant SGTs than in patients with benign SGTs. Mean lymphocyte percentage and NLR were significantly different between low- and high-grade malignant parotid gland tumors (P =.026 and P =.030, respectively). Conclusion Elevated NLR could be an inflammatory marker to distinguish low- from high-grade malignant parotid gland tumors. © Official journal of the American Academy of Otolaryngology-Head and Neck Surgery Foundation.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
high-grade malignant tumor
Konu Başlıkları
[dc.subject]
inflammatory marker
Konu Başlıkları
[dc.subject]
neutrophil-lymphocyte ratio
Konu Başlıkları
[dc.subject]
salivary gland tumors
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0194-5998
İlk Sayfa Sayısı
[dc.identifier.startpage]
988
Son Sayfa Sayısı
[dc.identifier.endpage]
996
Dergi Adı
[dc.relation.journal]
Otolaryngology - Head and Neck Surgery (United States)
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
155
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1177/0194599816659257
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7153
Görüntülenme Sayısı ( Şehir )
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Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
20
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Şubat 2024 05:59
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malignant patients tumors benign percentage high-grade parotid 103/mm3 lymphocyte between counts leukocytes significantly percentages marker inflammatory higher Objective Elevated Foundation Surgery Otolaryngology-Head Academy American journal Official distinguish Conclusion respectively) different distinguishing Subjects center referral Tertiary
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