Positive correlation of CRP and fibrinogen levels as cardiovascular risk factors in early stage of continuous ambulatory peritoneal dialysis patients

We aimed to study the relationship between the C-reactive protein (CRP), albumin, and fibrinogen as cardiovascular risk factors in continuous ambulatory peritoneal dialysis (CAPD) patients, in the early stage of their therapy. The study included 21 CAPD patients as the study group (SG) and age- and sex-matched 21 healthy patients as the control group (CG). History and physical exam data were obtained for all cases, and demographic baseline characteristics were taken. Twelve-hour fasting serum levels of glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, total protein, albumin, hemoglobin, CRP, and fibrinogen were obtained. There was no statistically significant difference between the SG and CG in baseline characteristics, including age, sex, body mass index (BMI), smoking, and family history of cardiovascular disease. However, diabetes mellitus (DM) and hypertension (HTN) were significantly more common among the study group. The average total protein, albumin, and hemoglobin levels were significantly lower, and the CRP and fibrinogen levels were significantly higher (p < 0.001) in the SG. A positive correlation was seen (r = 0.443, p < 0.05) among CRP and fibrinogen levels in SG. There was no correlation among the other parameters in SG. For CG, there was no correlation seen for any studied parameters. When patients with and without cardiovascular disease (CVD) were compared, no correlation was seen between CRP and other parameters. A positive correlation of CRP and fibrinogen levels as cardiovascular risk factors was shown in early stage of CAPD patients. The CAPD patients with elevated levels of CRP and fibrinogen should receive close follow-up for cardiovascular disease prevention. Copyright © Informa Healthcare USA, Inc.

Yazar Tekin I.O.
Pocan B.
Borazan A.
Ucar E.
Kuvandik G.
Ilikhan S.
Demircan N.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7063
Tek Biçim Adres 10.1080/08860220701813350
Konu Başlıkları Anticardiolipin antibodies
Chronic renal disease
Coronary angiography
Coronary artery disease
Echocardiography
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Renal Failure
Dergi Cilt Bilgisi 30
Dergi Sayısı 2
Sayfalar 219 - 225
Yayın Yılı 2008
Eser Adı
[dc.title]
Positive correlation of CRP and fibrinogen levels as cardiovascular risk factors in early stage of continuous ambulatory peritoneal dialysis patients
Yazar
[dc.contributor.author]
Tekin I.O.
Yazar
[dc.contributor.author]
Pocan B.
Yazar
[dc.contributor.author]
Borazan A.
Yazar
[dc.contributor.author]
Ucar E.
Yazar
[dc.contributor.author]
Kuvandik G.
Yazar
[dc.contributor.author]
Ilikhan S.
Yazar
[dc.contributor.author]
Demircan N.
Yayın Yılı
[dc.date.issued]
2008
Yayıncı
[dc.publisher]
Taylor and Francis Inc.
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
We aimed to study the relationship between the C-reactive protein (CRP), albumin, and fibrinogen as cardiovascular risk factors in continuous ambulatory peritoneal dialysis (CAPD) patients, in the early stage of their therapy. The study included 21 CAPD patients as the study group (SG) and age- and sex-matched 21 healthy patients as the control group (CG). History and physical exam data were obtained for all cases, and demographic baseline characteristics were taken. Twelve-hour fasting serum levels of glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, total protein, albumin, hemoglobin, CRP, and fibrinogen were obtained. There was no statistically significant difference between the SG and CG in baseline characteristics, including age, sex, body mass index (BMI), smoking, and family history of cardiovascular disease. However, diabetes mellitus (DM) and hypertension (HTN) were significantly more common among the study group. The average total protein, albumin, and hemoglobin levels were significantly lower, and the CRP and fibrinogen levels were significantly higher (p < 0.001) in the SG. A positive correlation was seen (r = 0.443, p < 0.05) among CRP and fibrinogen levels in SG. There was no correlation among the other parameters in SG. For CG, there was no correlation seen for any studied parameters. When patients with and without cardiovascular disease (CVD) were compared, no correlation was seen between CRP and other parameters. A positive correlation of CRP and fibrinogen levels as cardiovascular risk factors was shown in early stage of CAPD patients. The CAPD patients with elevated levels of CRP and fibrinogen should receive close follow-up for cardiovascular disease prevention. Copyright © Informa Healthcare USA, Inc.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Anticardiolipin antibodies
Konu Başlıkları
[dc.subject]
Chronic renal disease
Konu Başlıkları
[dc.subject]
Coronary angiography
Konu Başlıkları
[dc.subject]
Coronary artery disease
Konu Başlıkları
[dc.subject]
Echocardiography
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0886022X
İlk Sayfa Sayısı
[dc.identifier.startpage]
219
Son Sayfa Sayısı
[dc.identifier.endpage]
225
Dergi Adı
[dc.relation.journal]
Renal Failure
Dergi Sayısı
[dc.identifier.issue]
2
Dergi Cilt Bilgisi
[dc.identifier.volume]
30
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1080/08860220701813350
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7063
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
17
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Şubat 2024 09:08
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fibrinogen patients levels cardiovascular correlation cholesterol parameters significantly disease albumin protein between positive factors hemoglobin characteristics baseline obtained higher Informa hypertension Healthcare common average should Copyright elevated compared without studied mellitus receive follow-up prevention diabetes
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