Fournier's Gangrene: Overview of Prognostic Factors and Definition of New Prognostic Parameter

Objectives: To identify the prognostic factors and the new parameters that might predict a worse outcome in nonsurvivors compared with survivors of Fournier's gangrene (FG) and evaluated the validity of the Fournier's Gangrene Severity Index (FGSI) in patients with FG. Methods: The medical records of 18 patients with FG who were treated and followed up in our clinic were reviewed. Data were collected in terms of medical history, symptoms, and physical examination findings. The biochemical, hematologic, and bacteriologic study (aerobic and anaeorobic wound cultures) results at admission and at the final evaluation, the physical examination findings, the timing and extent of surgical debridement, and the antibiotic therapy were also recorded. The Charlson Comorbidity Index (CCI) and FGSI were evaluated stratified by survival. Results: The results were evaluated for 2 groups: those who survived (n = 14) and those who did not (n = 4). The admission FGSI score was 5.00 ± 2.91 (range 0-10) for survivors compared with 13.5 ± 2.62 (range 9-15) for nonsurvivors (P = .001). The CCI score was 3 ± 1.5 in survivors and 7 ± 2.2 in nonsurvivors (P = .008). Individual laboratory parameters such as hypomagnesemia, hemoglobin, hematocrit, alkaline phosphatase, creatinine, and the heart and respiratory rates were associated with a worse prognosis. In addition, a FGSI >9, rectal involvement, colostomy diversion, and a high CCI were associated with high mortality. Conclusions: Low magnesium levels might be a new parameter for a worse prognosis. High CCI and FGSI scores might be associated with a worse prognosis in patients with FG. A FGSI threshold of 9 was a predictor of mortality during the initial assessment. © 2010 Elsevier Inc. All rights reserved.

Yazar Erol B.
Tuncel A.
Hanci V.
Tokgoz H.
Yildiz A.
Akduman B.
Kargi E.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/5919
Tek Biçim Adres 10.1016/j.urology.2009.08.090
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Urology
Dergi Cilt Bilgisi 75
Dergi Sayısı 5
Sayfalar 1193 - 1198
Yayın Yılı 2010
Eser Adı
[dc.title]
Fournier's Gangrene: Overview of Prognostic Factors and Definition of New Prognostic Parameter
Yazar
[dc.contributor.author]
Erol B.
Yazar
[dc.contributor.author]
Tuncel A.
Yazar
[dc.contributor.author]
Hanci V.
Yazar
[dc.contributor.author]
Tokgoz H.
Yazar
[dc.contributor.author]
Yildiz A.
Yazar
[dc.contributor.author]
Akduman B.
Yazar
[dc.contributor.author]
Kargi E.
Yayın Yılı
[dc.date.issued]
2010
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objectives: To identify the prognostic factors and the new parameters that might predict a worse outcome in nonsurvivors compared with survivors of Fournier's gangrene (FG) and evaluated the validity of the Fournier's Gangrene Severity Index (FGSI) in patients with FG. Methods: The medical records of 18 patients with FG who were treated and followed up in our clinic were reviewed. Data were collected in terms of medical history, symptoms, and physical examination findings. The biochemical, hematologic, and bacteriologic study (aerobic and anaeorobic wound cultures) results at admission and at the final evaluation, the physical examination findings, the timing and extent of surgical debridement, and the antibiotic therapy were also recorded. The Charlson Comorbidity Index (CCI) and FGSI were evaluated stratified by survival. Results: The results were evaluated for 2 groups: those who survived (n = 14) and those who did not (n = 4). The admission FGSI score was 5.00 ± 2.91 (range 0-10) for survivors compared with 13.5 ± 2.62 (range 9-15) for nonsurvivors (P = .001). The CCI score was 3 ± 1.5 in survivors and 7 ± 2.2 in nonsurvivors (P = .008). Individual laboratory parameters such as hypomagnesemia, hemoglobin, hematocrit, alkaline phosphatase, creatinine, and the heart and respiratory rates were associated with a worse prognosis. In addition, a FGSI >9, rectal involvement, colostomy diversion, and a high CCI were associated with high mortality. Conclusions: Low magnesium levels might be a new parameter for a worse prognosis. High CCI and FGSI scores might be associated with a worse prognosis in patients with FG. A FGSI threshold of 9 was a predictor of mortality during the initial assessment. © 2010 Elsevier Inc. All rights reserved.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0090-4295
İlk Sayfa Sayısı
[dc.identifier.startpage]
1193
Son Sayfa Sayısı
[dc.identifier.endpage]
1198
Dergi Adı
[dc.relation.journal]
Urology
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
75
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.urology.2009.08.090
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/5919
Görüntülenme Sayısı ( Şehir )
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Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
195
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
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14 Temmuz 2024 21:39
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evaluated patients survivors prognosis associated nonsurvivors physical mortality examination findings results (range medical parameters compared Fournier admission hypomagnesemia alkaline hematocrit hemoglobin phosphatase Individual laboratory Objectives creatinine reserved rights Elsevier assessment initial during predictor threshold scores
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