HBsAg, anti-HCV, anti-HIV 1/2, and syphilis seroprevalence in blood donors in Eastern Marmara Region, Turkey and an overview of transfusion transmitted infections in Turkey

Introduction: Blood transfusion and component therapies are life-saving medical practices. However these therapies, are not without risks and may lead to the transmission of infectious agents from donor to recipient. Screening of blood donations for infectious agents is necessary to achieve transfusion safety. The aim of the study was to determine the six-years seroprevalence of HBV (hepatitis B virus), HCV (hepatitis C virus), HIV (human immunodeficiency virus), and syphilis in blood donors and to present an overview of transfusion transmitted infections in Turkey. Material and methods: A total of 150,787 volunteer blood donors who admitted to blood centers located in Eastern Marmara Region, Turkey between January 2009 and October 2014 were included in this study. HBsAg (hepatitis B surface antigen), anti-HCV (hepatitis C virus antibody), and HIV-1/2 antibody were detected by using Chemiluminescent Microparticle Enzyme Immunoassay (CMIA) method. Syphilis screening was performed by using VDRL (Venereal Disease Research Laboratory) test in the first three years and by CMIA-based treponemal test in the last three years. Results: Among the blood donors, 140,536 (93.2%) were male and 10,251 (6.8%) female. Out of all donors, 2,019 (1.33%) donors were positive for at least one screening test. The seroprevalence of HBV, HCV, HIV, and syphilis were 0.8 % (n=1340), 0.38% (n=578), 0,0025% (n=38) and 0,004 % (n=63), respectively. A significant decrease was observed in HBV seroprevalence by years (p < 0.005) Conclusion: The risk of transfusion-transmitted infections can be decreased by effectively using questionnaires and screening tests in blood donation centers, HBV vaccination programs, and awareness-raising activities. It is necessary to use improved screening methods for detection of transfusion-transmitted infection agents.

Yazar Altindis M.
Koroglu M.
Mutlu B.
Demiray T.
Dal T.
Sahin I.
Kulah C.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/6041
Tek Biçim Adres 10.19193/0393-6384_2016_2_51
Konu Başlıkları Anti-HCV
Anti-HIV
syphilis
Blood donors
HBsAg
Transfusion
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Acta Medica Mediterranea
Dergi Cilt Bilgisi 32
Dergi Sayısı 2
Sayfalar 343 - 347
Yayın Yılı 2016
Eser Adı
[dc.title]
HBsAg, anti-HCV, anti-HIV 1/2, and syphilis seroprevalence in blood donors in Eastern Marmara Region, Turkey and an overview of transfusion transmitted infections in Turkey
Yazar
[dc.contributor.author]
Altindis M.
Yazar
[dc.contributor.author]
Koroglu M.
Yazar
[dc.contributor.author]
Mutlu B.
Yazar
[dc.contributor.author]
Demiray T.
Yazar
[dc.contributor.author]
Dal T.
Yazar
[dc.contributor.author]
Sahin I.
Yazar
[dc.contributor.author]
Kulah C.
Yayın Yılı
[dc.date.issued]
2016
Yayıncı
[dc.publisher]
A. CARBONE Editore
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Introduction: Blood transfusion and component therapies are life-saving medical practices. However these therapies, are not without risks and may lead to the transmission of infectious agents from donor to recipient. Screening of blood donations for infectious agents is necessary to achieve transfusion safety. The aim of the study was to determine the six-years seroprevalence of HBV (hepatitis B virus), HCV (hepatitis C virus), HIV (human immunodeficiency virus), and syphilis in blood donors and to present an overview of transfusion transmitted infections in Turkey. Material and methods: A total of 150,787 volunteer blood donors who admitted to blood centers located in Eastern Marmara Region, Turkey between January 2009 and October 2014 were included in this study. HBsAg (hepatitis B surface antigen), anti-HCV (hepatitis C virus antibody), and HIV-1/2 antibody were detected by using Chemiluminescent Microparticle Enzyme Immunoassay (CMIA) method. Syphilis screening was performed by using VDRL (Venereal Disease Research Laboratory) test in the first three years and by CMIA-based treponemal test in the last three years. Results: Among the blood donors, 140,536 (93.2%) were male and 10,251 (6.8%) female. Out of all donors, 2,019 (1.33%) donors were positive for at least one screening test. The seroprevalence of HBV, HCV, HIV, and syphilis were 0.8 % (n=1340), 0.38% (n=578), 0,0025% (n=38) and 0,004 % (n=63), respectively. A significant decrease was observed in HBV seroprevalence by years (p < 0.005) Conclusion: The risk of transfusion-transmitted infections can be decreased by effectively using questionnaires and screening tests in blood donation centers, HBV vaccination programs, and awareness-raising activities. It is necessary to use improved screening methods for detection of transfusion-transmitted infection agents.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Anti-HCV
Konu Başlıkları
[dc.subject]
Anti-HIV
Konu Başlıkları
[dc.subject]
syphilis
Konu Başlıkları
[dc.subject]
Blood donors
Konu Başlıkları
[dc.subject]
HBsAg
Konu Başlıkları
[dc.subject]
Transfusion
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0393-6384
İlk Sayfa Sayısı
[dc.identifier.startpage]
343
Son Sayfa Sayısı
[dc.identifier.endpage]
347
Dergi Adı
[dc.relation.journal]
Acta Medica Mediterranea
Dergi Sayısı
[dc.identifier.issue]
2
Dergi Cilt Bilgisi
[dc.identifier.volume]
32
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.19193/0393-6384_2016_2_51
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/6041
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
6
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
04 Şubat 2024 03:57
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Tıklayınız
donors screening (hepatitis seroprevalence agents virus) transfusion infectious therapies methods Turkey infections syphilis necessary transfusion-transmitted centers improved positive detection infection CMIA-based Results female treponemal (n=578) awareness-raising effectively questionnaires Conclusion donation observed vaccination programs activities decrease
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