The effect of hemodialysis adequacy on ventricular repolarization in end-stage kidney disease

Objective: Ventricular repolarization (VR) markers may predict ventricular arrhythmias and cardiac arrest. The aim of this study was to investigate the acute effects of a hemodialysis (HD) session and HD adequacy on VR markers in HD patients. Methods: This cross-sectional study was conducted at 2 university hospitals with 83 patients and VR markers were measured before and after an HD session: QT, QTc, QT minimum, QT maximum, dispersion of QT (QTd), T-peak to T-end (Tp-e) interval, and Tp-e/QT. Kt/V measurements calculated using the second generation Daugirdas formula were used to indicate dialysis adequacy. The patients were divided into 2 groups according to the Kt/V value. Group 1 patients had a Kt/V of ?1.6 with a standard dialysis dose, and Group 2 comprised those with a measurement of >1.6 with a high dialysis dose. Results: There were 36 patients in Group 1 and 47 patients in Group 2. There were statistically significantly more female patients in Group 2 (p=0.016). After an HD session, heart rate increased, blood pressure decreased, and the QT, QTc, QT maximum, QTd, Tp-e interval, and Tp-e/QT were prolonged (p<0.05). The VR markers measured were similar in the 2 groups. VR markers were not significantly different in diabetic patients. Conclusion: HD may be a risk factor for cardiac arrest because of prolonged VR parameters, independent of HD adequacy. A high dialysis dose may not always be best for the heart. © 2019 Turkish Society of Cardiology

Yazar Kalaycı B.
Onan E.
Paydaş S.
Kaya B.
Adam Ü.
Besli S.
Kalaycı S.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/7943
Tek Biçim Adres 10.5543/tkda.2019.64359
Konu Başlıkları Dialysis dose
Hemodialysis
Hemodialysis adequacy
Kt/V
QT interval
Ventricular repolarization
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Turk Kardiyoloji Dernegi Arsivi
Dergi Cilt Bilgisi 47
Dergi Sayısı 7
Sayfalar 572 - 580
Yayın Yılı 2019
Eser Adı
[dc.title]
The effect of hemodialysis adequacy on ventricular repolarization in end-stage kidney disease
Yazar
[dc.contributor.author]
Kalaycı B.
Yazar
[dc.contributor.author]
Onan E.
Yazar
[dc.contributor.author]
Paydaş S.
Yazar
[dc.contributor.author]
Kaya B.
Yazar
[dc.contributor.author]
Adam Ü.
Yazar
[dc.contributor.author]
Besli S.
Yazar
[dc.contributor.author]
Kalaycı S.
Yayın Yılı
[dc.date.issued]
2019
Yayıncı
[dc.publisher]
Turkish Society of Cardiology
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective: Ventricular repolarization (VR) markers may predict ventricular arrhythmias and cardiac arrest. The aim of this study was to investigate the acute effects of a hemodialysis (HD) session and HD adequacy on VR markers in HD patients. Methods: This cross-sectional study was conducted at 2 university hospitals with 83 patients and VR markers were measured before and after an HD session: QT, QTc, QT minimum, QT maximum, dispersion of QT (QTd), T-peak to T-end (Tp-e) interval, and Tp-e/QT. Kt/V measurements calculated using the second generation Daugirdas formula were used to indicate dialysis adequacy. The patients were divided into 2 groups according to the Kt/V value. Group 1 patients had a Kt/V of ?1.6 with a standard dialysis dose, and Group 2 comprised those with a measurement of >1.6 with a high dialysis dose. Results: There were 36 patients in Group 1 and 47 patients in Group 2. There were statistically significantly more female patients in Group 2 (p=0.016). After an HD session, heart rate increased, blood pressure decreased, and the QT, QTc, QT maximum, QTd, Tp-e interval, and Tp-e/QT were prolonged (p<0.05). The VR markers measured were similar in the 2 groups. VR markers were not significantly different in diabetic patients. Conclusion: HD may be a risk factor for cardiac arrest because of prolonged VR parameters, independent of HD adequacy. A high dialysis dose may not always be best for the heart. © 2019 Turkish Society of Cardiology
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Dialysis dose
Konu Başlıkları
[dc.subject]
Hemodialysis
Konu Başlıkları
[dc.subject]
Hemodialysis adequacy
Konu Başlıkları
[dc.subject]
Kt/V
Konu Başlıkları
[dc.subject]
QT interval
Konu Başlıkları
[dc.subject]
Ventricular repolarization
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
1016-5169
İlk Sayfa Sayısı
[dc.identifier.startpage]
572
Son Sayfa Sayısı
[dc.identifier.endpage]
580
Dergi Adı
[dc.relation.journal]
Turk Kardiyoloji Dernegi Arsivi
Dergi Sayısı
[dc.identifier.issue]
7
Dergi Cilt Bilgisi
[dc.identifier.volume]
47
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.5543/tkda.2019.64359
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/7943
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
59
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
18 Mayıs 2024 11:21
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patients markers dialysis adequacy session measured maximum prolonged significantly Tp-e/QT interval cardiac groups arrest measurement Results female statistically Objective factor Society Turkish always independent parameters because increased Conclusion diabetic different similar decreased pressure generation comprised
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