Effect of sevoflurane–nitrous oxide induction on the incidence of rocuronium injection pain in adults

Objective: This randomized, prospective study was designed to investigate the effect of sevoflurane–nitrous oxide application on the incidence of the hand/arm withdrawal movement caused by rocuronium injection. Materials and Methods: There were 90 individuals undergoing elective surgery included in the study. After preoxygen-ation, Group T was given intravenous (i.v.) 5 mg/kg thiopental, Group S was given 7% sevoflurane and 40%/60% air/ O2, and Group N was given 7% sevoflurane and 40%/60% N2O/O2 for induction. After the eyelash reflex was lost, 0.6 mg/kg rocuronium was applied intravenously over 5 seconds, and then 2 ml saline was administered. Patients’ response to rocuronium injection was graded by using a 4-point scale (0–3). Hemodynamic data were recorded. Results: After the rocuronium injection, the mean arterial pressure (MAP) and heart rate (HR) values were different between the groups (p<0.05). The incidence of withdrawal movements associated with the injection of rocuronium was observed to be 96.7% in Group T (29/30), 73.3% in Group S (22/30), and 13.3% in Group N (4/30). There were significant differences between the groups (p<0.05). There were differences between Group T and Group S in terms of MAP and 4-point scale, and between Group N and Group S in terms of MAP, HR, and 4-point scale (p<0.05). Conclusions: Adding nitrous oxide to sevoflurane induction in adults reduces the incidence of withdrawal movements associated with rocuronium injection compared to thiopental induction. © 2017 by Erciyes University Faculty of Medicine.

Yazar Küçükosman G.
Pişkin Ö.
Hancı V.
Ayoğlu H.
Okyay D.
Yurtlu S.
Çalışkan A.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/5376
Tek Biçim Adres 10.5152/etd.2017.17011
Konu Başlıkları Nitrous oxide
Pain
Rocuronium
Sevoflurane
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
Dergi Adı Erciyes Medical Journal
Dergi Cilt Bilgisi 39
Dergi Sayısı 4
Sayfalar 149 - 153
Yayın Yılı 2017
Eser Adı
[dc.title]
Effect of sevoflurane–nitrous oxide induction on the incidence of rocuronium injection pain in adults
Yazar
[dc.contributor.author]
Küçükosman G.
Yazar
[dc.contributor.author]
Pişkin Ö.
Yazar
[dc.contributor.author]
Hancı V.
Yazar
[dc.contributor.author]
Ayoğlu H.
Yazar
[dc.contributor.author]
Okyay D.
Yazar
[dc.contributor.author]
Yurtlu S.
Yazar
[dc.contributor.author]
Çalışkan A.
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
AVES İbrahim KARA
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Objective: This randomized, prospective study was designed to investigate the effect of sevoflurane–nitrous oxide application on the incidence of the hand/arm withdrawal movement caused by rocuronium injection. Materials and Methods: There were 90 individuals undergoing elective surgery included in the study. After preoxygen-ation, Group T was given intravenous (i.v.) 5 mg/kg thiopental, Group S was given 7% sevoflurane and 40%/60% air/ O2, and Group N was given 7% sevoflurane and 40%/60% N2O/O2 for induction. After the eyelash reflex was lost, 0.6 mg/kg rocuronium was applied intravenously over 5 seconds, and then 2 ml saline was administered. Patients’ response to rocuronium injection was graded by using a 4-point scale (0–3). Hemodynamic data were recorded. Results: After the rocuronium injection, the mean arterial pressure (MAP) and heart rate (HR) values were different between the groups (p<0.05). The incidence of withdrawal movements associated with the injection of rocuronium was observed to be 96.7% in Group T (29/30), 73.3% in Group S (22/30), and 13.3% in Group N (4/30). There were significant differences between the groups (p<0.05). There were differences between Group T and Group S in terms of MAP and 4-point scale, and between Group N and Group S in terms of MAP, HR, and 4-point scale (p<0.05). Conclusions: Adding nitrous oxide to sevoflurane induction in adults reduces the incidence of withdrawal movements associated with rocuronium injection compared to thiopental induction. © 2017 by Erciyes University Faculty of Medicine.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Nitrous oxide
Konu Başlıkları
[dc.subject]
Pain
Konu Başlıkları
[dc.subject]
Rocuronium
Konu Başlıkları
[dc.subject]
Sevoflurane
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
2149-2247
İlk Sayfa Sayısı
[dc.identifier.startpage]
149
Son Sayfa Sayısı
[dc.identifier.endpage]
153
Dergi Adı
[dc.relation.journal]
Erciyes Medical Journal
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
39
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.5152/etd.2017.17011
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/5376
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
11
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
07 Nisan 2024 23:40
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rocuronium injection between induction sevoflurane 4-point incidence withdrawal 40%/60% associated groups thiopental movements differences University Hemodynamic Faculty Medicine recorded pressure Results different values arterial adults Conclusions Adding significant (4/30) (22/30) nitrous reduces Erciyes (29/30) compared
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