Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer in Untreated Patients with Obstructive Sleep Apnea-Hypopnea Syndrome: A Case–Control Study

Purpose: To evaluate peripapillary choroidal thickness (PPCT), central macular choroidal thickness (CMCT), and retinal nerve fiber layer (RNFL) thickness in untreated patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: This prospective, randomized, and comparative study was conducted in a university ophthalmology clinic. 106 eyes of 106 patients with OSAHS and 44 eyes of 44 healthy individuals were evaluated in this study. Only right eyes were evaluated. The patients with OSAHS were divided into three groups as mild (group 1), moderate (group 2), and severe (group 3) according to apnea-hypopnea index. The PPCT, CMCT, and RNFL measurements were performed by using spectral domain optical coherence tomography with enhanced depth imaging technique. The main parameters assessed were PPCT-Temporal, PPCT-Superior, PPCT-Nasal, PPCT-Inferior quadrants, CMCT, and RNFL thicknesses. Results: The PPCT of all quadrants was significantly thicker in the control group compared with the moderate and severe subgroups of OSAHS (p < 0.05). The PPCT-Superior and PPCT-Temporal were significantly thinner in the mild subgroup compared with the control group (p = 0.003 and p = 0.028, respectively). There was no difference between the control and mild groups regarding the RNFL thicknesses except nasal RNFL and inferotemporal RNFL which are thinner in the mild group. The RNFL thicknesses of all quadrants were significantly thicker in the control group compared with moderate and severe subgroups (p < 0.05). The CMCT was significantly thicker in the control group compared with all subgroups of OSAHS (p < 0.05). Conclusions: In OSAHS patients, PPCT, CMCT, and RNFL were significantly thinner compared with the control group. These results may explain why OSAHS patients are prone to normotensive glaucoma. © 2017 Taylor & Francis Group.

Yazar Yazgan S.
Erboy F.
Celik H.U.
Ornek T.
Ugurbas S.H.
Kokturk F.
Ayar O.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/6979
Tek Biçim Adres 10.1080/02713683.2016.1266661
Konu Başlıkları Obstructive sleep apnea-hypopnea syndrome
peripapillary choroidal thickness
retinal nerve fiber layer
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
Dergi Adı Current Eye Research
Dergi Cilt Bilgisi 42
Dergi Sayısı 11
Sayfalar 1552 - 1560
Yayın Yılı 2017
Eser Adı
[dc.title]
Peripapillary Choroidal Thickness and Retinal Nerve Fiber Layer in Untreated Patients with Obstructive Sleep Apnea-Hypopnea Syndrome: A Case–Control Study
Yazar
[dc.contributor.author]
Yazgan S.
Yazar
[dc.contributor.author]
Erboy F.
Yazar
[dc.contributor.author]
Celik H.U.
Yazar
[dc.contributor.author]
Ornek T.
Yazar
[dc.contributor.author]
Ugurbas S.H.
Yazar
[dc.contributor.author]
Kokturk F.
Yazar
[dc.contributor.author]
Ayar O.
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
Taylor and Francis Ltd
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose: To evaluate peripapillary choroidal thickness (PPCT), central macular choroidal thickness (CMCT), and retinal nerve fiber layer (RNFL) thickness in untreated patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: This prospective, randomized, and comparative study was conducted in a university ophthalmology clinic. 106 eyes of 106 patients with OSAHS and 44 eyes of 44 healthy individuals were evaluated in this study. Only right eyes were evaluated. The patients with OSAHS were divided into three groups as mild (group 1), moderate (group 2), and severe (group 3) according to apnea-hypopnea index. The PPCT, CMCT, and RNFL measurements were performed by using spectral domain optical coherence tomography with enhanced depth imaging technique. The main parameters assessed were PPCT-Temporal, PPCT-Superior, PPCT-Nasal, PPCT-Inferior quadrants, CMCT, and RNFL thicknesses. Results: The PPCT of all quadrants was significantly thicker in the control group compared with the moderate and severe subgroups of OSAHS (p < 0.05). The PPCT-Superior and PPCT-Temporal were significantly thinner in the mild subgroup compared with the control group (p = 0.003 and p = 0.028, respectively). There was no difference between the control and mild groups regarding the RNFL thicknesses except nasal RNFL and inferotemporal RNFL which are thinner in the mild group. The RNFL thicknesses of all quadrants were significantly thicker in the control group compared with moderate and severe subgroups (p < 0.05). The CMCT was significantly thicker in the control group compared with all subgroups of OSAHS (p < 0.05). Conclusions: In OSAHS patients, PPCT, CMCT, and RNFL were significantly thinner compared with the control group. These results may explain why OSAHS patients are prone to normotensive glaucoma. © 2017 Taylor & Francis Group.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Obstructive sleep apnea-hypopnea syndrome
Konu Başlıkları
[dc.subject]
peripapillary choroidal thickness
Konu Başlıkları
[dc.subject]
retinal nerve fiber layer
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0271-3683
İlk Sayfa Sayısı
[dc.identifier.startpage]
1552
Son Sayfa Sayısı
[dc.identifier.endpage]
1560
Dergi Adı
[dc.relation.journal]
Current Eye Research
Dergi Sayısı
[dc.identifier.issue]
11
Dergi Cilt Bilgisi
[dc.identifier.volume]
42
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1080/02713683.2016.1266661
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/6979
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
28
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 20:05
Google Kontrol
Tıklayınız
control compared patients significantly thinner (group moderate severe subgroups quadrants thicker thicknesses thickness PPCT-Superior evaluated PPCT-Temporal groups apnea-hypopnea choroidal PPCT-Inferior Results PPCT-Nasal Purpose subgroup Francis Taylor glaucoma normotensive explain results Conclusions inferotemporal except regarding between
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms