Effect of rapid-eye-movement sleep deprivation on rat hypothalamic prostaglandins

In this study, we investigated thyroid hormones, thyroid stimulating hormone (TSH), prostaglandin D2 (PGD2) and prostaglandin E2 (PGE2) levels in rapid-eye-movement (REM) sleep-deprived rats compared with controls. The aim of the present study was to detect the effect of REM sleep deprivation (RSD) especially on hypothalamic prostaglandin levels. Twenty-seven male rats were randomly assigned in three groups as dry cage control, yoked control, and RSD. RSD rats were sleep deprived for 10 consecutive days. At the end of 10th day all rats were sacrificed for measurement. Our results indicated that total triiodothyronine (T3) and thyroxine (T4) decreased in the RSD group while there was no change in TSH. We also measured hypothalamic PGD2 and PGE2 levels, but we could not find any significant change between groups. © 2005 Elsevier Ltd. All rights reserved.

Yazar Gelir E.
Arslan S.O.
Sayan H.
Pinar L.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/5369
Tek Biçim Adres 10.1016/j.plefa.2005.05.021
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Prostaglandins Leukotrienes and Essential Fatty Acids
Dergi Cilt Bilgisi 73
Dergi Sayısı 5
Sayfalar 391 - 396
Yayın Yılı 2005
Eser Adı
[dc.title]
Effect of rapid-eye-movement sleep deprivation on rat hypothalamic prostaglandins
Yazar
[dc.contributor.author]
Gelir E.
Yazar
[dc.contributor.author]
Arslan S.O.
Yazar
[dc.contributor.author]
Sayan H.
Yazar
[dc.contributor.author]
Pinar L.
Yayın Yılı
[dc.date.issued]
2005
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
In this study, we investigated thyroid hormones, thyroid stimulating hormone (TSH), prostaglandin D2 (PGD2) and prostaglandin E2 (PGE2) levels in rapid-eye-movement (REM) sleep-deprived rats compared with controls. The aim of the present study was to detect the effect of REM sleep deprivation (RSD) especially on hypothalamic prostaglandin levels. Twenty-seven male rats were randomly assigned in three groups as dry cage control, yoked control, and RSD. RSD rats were sleep deprived for 10 consecutive days. At the end of 10th day all rats were sacrificed for measurement. Our results indicated that total triiodothyronine (T3) and thyroxine (T4) decreased in the RSD group while there was no change in TSH. We also measured hypothalamic PGD2 and PGE2 levels, but we could not find any significant change between groups. © 2005 Elsevier Ltd. All rights reserved.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0952-3278
İlk Sayfa Sayısı
[dc.identifier.startpage]
391
Son Sayfa Sayısı
[dc.identifier.endpage]
396
Dergi Adı
[dc.relation.journal]
Prostaglandins Leukotrienes and Essential Fatty Acids
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
73
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.plefa.2005.05.021
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/5369
Görüntülenme Sayısı ( Şehir )
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Görüntülenme
6
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Şubat 2024 00:37
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levels prostaglandin groups hypothalamic control thyroid change decreased thyroxine triiodothyronine indicated results measurement sacrificed reserved rights Elsevier between significant measured rapid-eye-movement controls compared sleep-deprived (PGE2) (PGD2) hormone stimulating hormones investigated present detect consecutive deprived assigned
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