Corneal biomechanical comparison of pseudoexfoliation syndrome, pseudoexfoliative glaucoma and healthy subjects

Purpose: To evaluate the differences in corneal biomechanical properties between healthy subjects and patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliative glaucoma (PEXG) using the ocular response analyzer (ORA). Materials and methods: One hundred eighteen eyes of 45 healthy, 43 PEX and 30 PEXG eyes were included in to the study. Corneal biomechanical parameters measurements were obtained using ORA. The main parameters assessed were corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated pressure measurement (IOPg) and corneal compensated intraocular pressure (IOPcc). Ultrasound pachymetry was used for measurement of central corneal thickness (CCT). Results: In healthy subjects, PEX and PEXG eyes' mean CH values were 10.3±1.4, 8.2±1.4 and 6.8±1.7mmHg, respectively. The difference in mean CH between the PEXG and other two groups were statistically significant (p<0.001). Mean CRF values were 10.3±0.7, 7.9±1.6 and 7.9±1.9mmHg, in healthy subjects PEX and PEXG, respectively. The difference in mean CRF between the PEX and PEXG was not statistically significant (p=0.630), however the mean CRF was significantly higher in healthy subjects, compared to other two groups. Mean CCT were 546.3±28, 525.5±35 and 509±36µ, in healthy subjects, PEX and PEXG, respectively. The differences on CCT were also significant among the three groups (p<0.001). Conclusion: In this study, the corneal biomechanical features of subjects with PEX were found to be changed as compared to healthy controls. In these patients; CH, CRF and CCT were decreased which was more obvious in patients with PEXG in comparison to PEX patients. © 2014 Informa Healthcare USA, Inc. All rights reserved.

Dergi Adı Current Eye Research
Dergi Cilt Bilgisi 40
Dergi Sayısı 5
Sayfalar 470 - 475
Yayın Yılı 2015
Eser Adı
[dc.title]
Corneal biomechanical comparison of pseudoexfoliation syndrome, pseudoexfoliative glaucoma and healthy subjects
Yazar
[dc.contributor.author]
Yazgan S.
Yazar
[dc.contributor.author]
Celik U.
Yazar
[dc.contributor.author]
Alagöz N.
Yazar
[dc.contributor.author]
Taş M.
Yayın Yılı
[dc.date.issued]
2015
Yayıncı
[dc.publisher]
Informa Healthcare
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose: To evaluate the differences in corneal biomechanical properties between healthy subjects and patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliative glaucoma (PEXG) using the ocular response analyzer (ORA). Materials and methods: One hundred eighteen eyes of 45 healthy, 43 PEX and 30 PEXG eyes were included in to the study. Corneal biomechanical parameters measurements were obtained using ORA. The main parameters assessed were corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated pressure measurement (IOPg) and corneal compensated intraocular pressure (IOPcc). Ultrasound pachymetry was used for measurement of central corneal thickness (CCT). Results: In healthy subjects, PEX and PEXG eyes' mean CH values were 10.3±1.4, 8.2±1.4 and 6.8±1.7mmHg, respectively. The difference in mean CH between the PEXG and other two groups were statistically significant (p<0.001). Mean CRF values were 10.3±0.7, 7.9±1.6 and 7.9±1.9mmHg, in healthy subjects PEX and PEXG, respectively. The difference in mean CRF between the PEX and PEXG was not statistically significant (p=0.630), however the mean CRF was significantly higher in healthy subjects, compared to other two groups. Mean CCT were 546.3±28, 525.5±35 and 509±36µ, in healthy subjects, PEX and PEXG, respectively. The differences on CCT were also significant among the three groups (p<0.001). Conclusion: In this study, the corneal biomechanical features of subjects with PEX were found to be changed as compared to healthy controls. In these patients; CH, CRF and CCT were decreased which was more obvious in patients with PEXG in comparison to PEX patients. © 2014 Informa Healthcare USA, Inc. All rights reserved.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Corneal biomechanics
Konu Başlıkları
[dc.subject]
Glaucoma
Konu Başlıkları
[dc.subject]
Ocular response analyzer
Konu Başlıkları
[dc.subject]
Pseudoexfoliation syndrome
Konu Başlıkları
[dc.subject]
Pseudoexfoliative glaucoma
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0271-3683
İlk Sayfa Sayısı
[dc.identifier.startpage]
470
Son Sayfa Sayısı
[dc.identifier.endpage]
475
Dergi Adı
[dc.relation.journal]
Current Eye Research
Dergi Sayısı
[dc.identifier.issue]
5
Dergi Cilt Bilgisi
[dc.identifier.volume]
40
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.3109/02713683.2014.930157
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4917
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
13
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
06 Şubat 2024 18:42
Google Kontrol
Tıklayınız
healthy corneal subjects patients groups significant between biomechanical respectively measurement pressure compared values statistically difference parameters differences Conclusion decreased obvious comparison Informa Healthcare rights reserved controls 509±36µ features changed higher significantly however Purpose analyzer included
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

creativecommons
Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.
Platforms