Comparison of propofol-dexmedetomidine, tiopental-dexmedetomidine and etomidate-dexmedetomidine combinations' effects on the tracheal intubation conditions without using muscle relaxants

Background: In our study, we aimed to compare the endotracheal intubation conditions without muscle relaxants during induction with the combinations of dexmedotimidine-propofol, dexmedotimidine-thiopenthal and dexmedetomidine-etomidate. Method: Seventy-six patients, in ASA risk group I-II, between ages 20-60 years, with Mallampati Class 1 were included in the study. All patients were premedicated with midazolam. The patients were randomly divided into three groups as Group P (n=30, dexmedetomidine-propofol), Group T (n=30, dexmedetomidine-thiopenthal), Group E (n=16, dexmedetomidine-etomidate). All patients received dexmedetomidine 1 µg.kg-1 in 10 min. Then, the patients were administered 2.5 mg.kg-1 propofol for Group P, 5 mg.kg-1 thiopental for Group T and 0.3 mg.kg-1 etomidate for Group E during induction. Hemodynamic data of the patients were recorded before induction, after dexmedetomidine administration, immediately after intubation and 3, 5 and 10 minutes after intubation. Results: There was no difference between the groups according to hemodynamic data. Sixteen patients in Group P and 10 patients in Group T had acceptable intubation conditions. Muscle relaxant was needed in 14, 20 and 16 patients in Groups P, T and E, respectively (p<0.05). Conclusion: In conclusion, we determined that best intubation conditions without muscle relaxants were achieved with propofol-dexmedetomidine combination. None of the patients receiving etomidate -dexmedetomidine combination could be intubated without muscle relaxants (Tab. 6, Ref. 29). Full Text in PDF www.elis.sk.

Yazar Bollucuoglu K.
Hanci V.
Yurtlu S.
Okyay D.
Ayoglu H.
Turan I.O.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/4827
Tek Biçim Adres 10.4149/BLL_2013_107
Konu Başlıkları Dexmedetomidine
Etomidate
Intubation without muscle relaxants
Propofol
Thiopental
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Bratislava Medical Journal
Dergi Cilt Bilgisi 114
Dergi Sayısı 9
Sayfalar 514 - 518
Yayın Yılı 2013
Eser Adı
[dc.title]
Comparison of propofol-dexmedetomidine, tiopental-dexmedetomidine and etomidate-dexmedetomidine combinations' effects on the tracheal intubation conditions without using muscle relaxants
Yazar
[dc.contributor.author]
Bollucuoglu K.
Yazar
[dc.contributor.author]
Hanci V.
Yazar
[dc.contributor.author]
Yurtlu S.
Yazar
[dc.contributor.author]
Okyay D.
Yazar
[dc.contributor.author]
Ayoglu H.
Yazar
[dc.contributor.author]
Turan I.O.
Yayın Yılı
[dc.date.issued]
2013
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Background: In our study, we aimed to compare the endotracheal intubation conditions without muscle relaxants during induction with the combinations of dexmedotimidine-propofol, dexmedotimidine-thiopenthal and dexmedetomidine-etomidate. Method: Seventy-six patients, in ASA risk group I-II, between ages 20-60 years, with Mallampati Class 1 were included in the study. All patients were premedicated with midazolam. The patients were randomly divided into three groups as Group P (n=30, dexmedetomidine-propofol), Group T (n=30, dexmedetomidine-thiopenthal), Group E (n=16, dexmedetomidine-etomidate). All patients received dexmedetomidine 1 µg.kg-1 in 10 min. Then, the patients were administered 2.5 mg.kg-1 propofol for Group P, 5 mg.kg-1 thiopental for Group T and 0.3 mg.kg-1 etomidate for Group E during induction. Hemodynamic data of the patients were recorded before induction, after dexmedetomidine administration, immediately after intubation and 3, 5 and 10 minutes after intubation. Results: There was no difference between the groups according to hemodynamic data. Sixteen patients in Group P and 10 patients in Group T had acceptable intubation conditions. Muscle relaxant was needed in 14, 20 and 16 patients in Groups P, T and E, respectively (p<0.05). Conclusion: In conclusion, we determined that best intubation conditions without muscle relaxants were achieved with propofol-dexmedetomidine combination. None of the patients receiving etomidate -dexmedetomidine combination could be intubated without muscle relaxants (Tab. 6, Ref. 29). Full Text in PDF www.elis.sk.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Dexmedetomidine
Konu Başlıkları
[dc.subject]
Etomidate
Konu Başlıkları
[dc.subject]
Intubation without muscle relaxants
Konu Başlıkları
[dc.subject]
Propofol
Konu Başlıkları
[dc.subject]
Thiopental
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0006-9248
İlk Sayfa Sayısı
[dc.identifier.startpage]
514
Son Sayfa Sayısı
[dc.identifier.endpage]
518
Dergi Adı
[dc.relation.journal]
Bratislava Medical Journal
Dergi Sayısı
[dc.identifier.issue]
9
Dergi Cilt Bilgisi
[dc.identifier.volume]
114
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.4149/BLL_2013_107
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4827
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
23
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Nisan 2024 02:25
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Tıklayınız
patients intubation induction without relaxants muscle conditions between dexmedetomidine combination groups etomidate during relaxant needed Muscle acceptable Sixteen hemodynamic according difference Results Groups intubated -dexmedetomidine receiving propofol-dexmedetomidine achieved minutes determined conclusion Conclusion respectively Background immediately
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