Cytological features of pure micropapillary carcinoma of various organs: A report of eight cases

Micropapillary carcinoma (MPC) is a rare aggressive tumor, which generally accompanies the primary carcinoma of the organ of its origin, while the pure form is extremely uncommon. Angiolymphatic involvement is widespread and a considerable proportion of the cases present with metastases. The current study presents eight pure MPC cases arising from the breast (n=3), urinary bladder (n=3), parotid gland (n=1) and lung (n=1, presenting with pericardial effusion), with the cytological findings. The eight patients included three female and five male cases aged between 48 and 74 years. The most common cytological findings were three-dimensional aggregates, cell clusters with angulated or scalloped borders, single cells with a columnar configuration and eccentric nuclei, and high-grade nuclear features. Histopathological sections showed accompanying in situ ductal carcinoma in the cases of MPC arising in the parotid gland and breast (n=3), and one case in the bladder exhibited only in situ MPC. The average follow-up period was 20 months (range, 6-54 months) and, during this period, three patients succumbed to the disease. At present, four patients are alive with disease and one patient is alive and disease-free. In conclusion, cytology is an important tool for the diagnosis and management of MPC.

Yazar Huq G.E.
Canberk Ş.
Öznur M.
Yildiz P.
Bahadir B.
Behzatoglu K.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/4972
Tek Biçim Adres 10.3892/ol.2014.2198
Konu Başlıkları Breast
Cytology
Lung
Micropapillary carcinoma
Parotid
Urinary bladder
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Oncology Letters
Dergi Cilt Bilgisi 8
Dergi Sayısı 2
Sayfalar 705 - 710
Yayın Yılı 2014
Eser Adı
[dc.title]
Cytological features of pure micropapillary carcinoma of various organs: A report of eight cases
Yazar
[dc.contributor.author]
Huq G.E.
Yazar
[dc.contributor.author]
Canberk Ş.
Yazar
[dc.contributor.author]
Öznur M.
Yazar
[dc.contributor.author]
Yildiz P.
Yazar
[dc.contributor.author]
Bahadir B.
Yazar
[dc.contributor.author]
Behzatoglu K.
Yayın Yılı
[dc.date.issued]
2014
Yayıncı
[dc.publisher]
Spandidos Publications
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Micropapillary carcinoma (MPC) is a rare aggressive tumor, which generally accompanies the primary carcinoma of the organ of its origin, while the pure form is extremely uncommon. Angiolymphatic involvement is widespread and a considerable proportion of the cases present with metastases. The current study presents eight pure MPC cases arising from the breast (n=3), urinary bladder (n=3), parotid gland (n=1) and lung (n=1, presenting with pericardial effusion), with the cytological findings. The eight patients included three female and five male cases aged between 48 and 74 years. The most common cytological findings were three-dimensional aggregates, cell clusters with angulated or scalloped borders, single cells with a columnar configuration and eccentric nuclei, and high-grade nuclear features. Histopathological sections showed accompanying in situ ductal carcinoma in the cases of MPC arising in the parotid gland and breast (n=3), and one case in the bladder exhibited only in situ MPC. The average follow-up period was 20 months (range, 6-54 months) and, during this period, three patients succumbed to the disease. At present, four patients are alive with disease and one patient is alive and disease-free. In conclusion, cytology is an important tool for the diagnosis and management of MPC.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Breast
Konu Başlıkları
[dc.subject]
Cytology
Konu Başlıkları
[dc.subject]
Lung
Konu Başlıkları
[dc.subject]
Micropapillary carcinoma
Konu Başlıkları
[dc.subject]
Parotid
Konu Başlıkları
[dc.subject]
Urinary bladder
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
1792-1074
İlk Sayfa Sayısı
[dc.identifier.startpage]
705
Son Sayfa Sayısı
[dc.identifier.endpage]
710
Dergi Adı
[dc.relation.journal]
Oncology Letters
Dergi Sayısı
[dc.identifier.issue]
2
Dergi Cilt Bilgisi
[dc.identifier.volume]
8
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.3892/ol.2014.2198
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4972
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
18
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
18 Şubat 2024 10:33
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Tıklayınız
patients carcinoma present findings cytological arising breast bladder parotid disease period nuclei columnar average configuration eccentric ductal high-grade exhibited nuclear features Histopathological sections showed accompanying Micropapillary follow-up management diagnosis important cytology conclusion disease-free patient succumbed
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