Antibacterial chitosan/silk sericin 3D porous scaffolds as a wound dressing material

Antimicrobial mixed dressings have traditionally been used to minimize bacterial infection of burns and other wounds. This study presents the advancement of biocompatible chitosan/silk sericin (CHT/SS) scaffolds combined with lauric acid (LA) and zinc oxide nanoparticles (nZnO) for the successful wound dressing applications. Antibacterial assay results showed that the diameters of the inhibition zone increased from 2 ± 0.4 to 7 ± 0.1 mm for Escherichia coli, as well as from 2.5 ± 0.2 to 6 ± 0.4 mm for Staphylococcus aureus while CHTS/SS/100nZnO compared to CHT/SS/0.01LA. The results not only showed excellent inhibition against Gram-positive and Gram-negative bacterial growth but also revealed improved proliferation and extended viability for HaCaT cells. © 2016 Informa UK Limited, trading as Taylor & Francis Group.

Yazar Karahaliloglu Z.
Kilicay E.
Denkbas E.B.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/4302
Tek Biçim Adres 10.1080/21691401.2016.1203796
Konu Başlıkları Chitosan
lauric acid
silk sericin
wound dressing
zinc oxide nanoparticles
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Artificial Cells, Nanomedicine and Biotechnology
Dergi Cilt Bilgisi 45
Dergi Sayısı 6
Sayfalar 1172 - 1185
Yayın Yılı 2017
Eser Adı
[dc.title]
Antibacterial chitosan/silk sericin 3D porous scaffolds as a wound dressing material
Yazar
[dc.contributor.author]
Karahaliloglu Z.
Yazar
[dc.contributor.author]
Kilicay E.
Yazar
[dc.contributor.author]
Denkbas E.B.
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
Taylor and Francis Ltd.
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Antimicrobial mixed dressings have traditionally been used to minimize bacterial infection of burns and other wounds. This study presents the advancement of biocompatible chitosan/silk sericin (CHT/SS) scaffolds combined with lauric acid (LA) and zinc oxide nanoparticles (nZnO) for the successful wound dressing applications. Antibacterial assay results showed that the diameters of the inhibition zone increased from 2 ± 0.4 to 7 ± 0.1 mm for Escherichia coli, as well as from 2.5 ± 0.2 to 6 ± 0.4 mm for Staphylococcus aureus while CHTS/SS/100nZnO compared to CHT/SS/0.01LA. The results not only showed excellent inhibition against Gram-positive and Gram-negative bacterial growth but also revealed improved proliferation and extended viability for HaCaT cells. © 2016 Informa UK Limited, trading as Taylor & Francis Group.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Chitosan
Konu Başlıkları
[dc.subject]
lauric acid
Konu Başlıkları
[dc.subject]
silk sericin
Konu Başlıkları
[dc.subject]
wound dressing
Konu Başlıkları
[dc.subject]
zinc oxide nanoparticles
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
2169-1401
İlk Sayfa Sayısı
[dc.identifier.startpage]
1172
Son Sayfa Sayısı
[dc.identifier.endpage]
1185
Dergi Adı
[dc.relation.journal]
Artificial Cells, Nanomedicine and Biotechnology
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
45
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1080/21691401.2016.1203796
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4302
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
9
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
08 Kasım 2023 16:02
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Tıklayınız
bacterial showed results inhibition Antimicrobial CHT/SS/0 CHTS/SS/100nZnO compared aureus Staphylococcus Gram-negative Francis Taylor trading Limited Informa excellent viability extended proliferation improved revealed growth Gram-positive against Escherichia increased wounds sericin chitosan/silk biocompatible advancement presents scaffolds infection
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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