Boxing as a sport activity associated with isolated GH deficiency

Traumatic brain injury (TBI) has long been known as a cause of hypopituitarism, and it is characterized by a high prevalence of neuroendocrine abnormalities. Boxing, one of most common combative sports, may also result in TBI. As far as we know, pituitary functions including GH status have not been investigated in boxers. Therefore, in this preliminary study, have assessed the pituitary functions in boxers. Eleven actively competing or retired male boxers with a mean age of 38.0±3.6 yr and 7 age -, sex- and BMI -matched healthy non- boxing controls were included in the study. Biochemical and basal hormonal parameters including IGF - I levels were measured. To assess GH secretory status in boxers and healthy controls, GHRH (1 µg/ + GHRP- 6 (1 µg/kg) test was performed. After GHRH+ GHRP- 6 test, mean peak GH level boxers and in controls were 10.9±1.7 and 41.4±6.7 µg/l, respectively (p < 0.05). Peak GH levels 5 (45%) boxers were found to be lower than 10 µg/l and considered as severe GH deficient. In control group, mean IGF - I levels (367±18.8 ng/ml) were significantly higher than that obtained boxers (237±23.3 ng/dl) (p <0.01). All the other pituitary hormones were normal including ADH no signs and symptoms of diabetes insipidus. There was a significant negative correlation between peak GH levels and boxing duration, and between peak GH levels and number of bouts. In conclu sion, we think that boxing is a cause of TBI, and GH deficiency is very common among boxers. Further studies including large number of boxers, both professional and amateur, are needed clarify pituitary dysfunction in boxers. ©2004, Editrice Kurtis.

Yazar Kelestimur F.
Tanriverdi F.
Atmaca H.
KUnluhizarci
Selcuklu A.
Casanueva F.F.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/4534
Tek Biçim Adres 10.1007/BF03345299
Konu Başlıkları Boxer
GH deficiency
Pituitary
Traumatic brain injury
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Journal of Endocrinological Investigation
Dergi Cilt Bilgisi 27
Dergi Sayısı 11
Sayfalar RC28 - RC32
Yayın Yılı 2004
Eser Adı
[dc.title]
Boxing as a sport activity associated with isolated GH deficiency
Yazar
[dc.contributor.author]
Kelestimur F.
Yazar
[dc.contributor.author]
Tanriverdi F.
Yazar
[dc.contributor.author]
Atmaca H.
Yazar
[dc.contributor.author]
KUnluhizarci
Yazar
[dc.contributor.author]
Selcuklu A.
Yazar
[dc.contributor.author]
Casanueva F.F.
Yayın Yılı
[dc.date.issued]
2004
Yayıncı
[dc.publisher]
Springer International Publishing
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Traumatic brain injury (TBI) has long been known as a cause of hypopituitarism, and it is characterized by a high prevalence of neuroendocrine abnormalities. Boxing, one of most common combative sports, may also result in TBI. As far as we know, pituitary functions including GH status have not been investigated in boxers. Therefore, in this preliminary study, have assessed the pituitary functions in boxers. Eleven actively competing or retired male boxers with a mean age of 38.0±3.6 yr and 7 age -, sex- and BMI -matched healthy non- boxing controls were included in the study. Biochemical and basal hormonal parameters including IGF - I levels were measured. To assess GH secretory status in boxers and healthy controls, GHRH (1 µg/ + GHRP- 6 (1 µg/kg) test was performed. After GHRH+ GHRP- 6 test, mean peak GH level boxers and in controls were 10.9±1.7 and 41.4±6.7 µg/l, respectively (p < 0.05). Peak GH levels 5 (45%) boxers were found to be lower than 10 µg/l and considered as severe GH deficient. In control group, mean IGF - I levels (367±18.8 ng/ml) were significantly higher than that obtained boxers (237±23.3 ng/dl) (p <0.01). All the other pituitary hormones were normal including ADH no signs and symptoms of diabetes insipidus. There was a significant negative correlation between peak GH levels and boxing duration, and between peak GH levels and number of bouts. In conclu sion, we think that boxing is a cause of TBI, and GH deficiency is very common among boxers. Further studies including large number of boxers, both professional and amateur, are needed clarify pituitary dysfunction in boxers. ©2004, Editrice Kurtis.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Boxer
Konu Başlıkları
[dc.subject]
GH deficiency
Konu Başlıkları
[dc.subject]
Pituitary
Konu Başlıkları
[dc.subject]
Traumatic brain injury
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
0391-4097
İlk Sayfa Sayısı
[dc.identifier.startpage]
RC28
Son Sayfa Sayısı
[dc.identifier.endpage]
RC32
Dergi Adı
[dc.relation.journal]
Journal of Endocrinological Investigation
Dergi Sayısı
[dc.identifier.issue]
11
Dergi Cilt Bilgisi
[dc.identifier.volume]
27
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1007/BF03345299
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4534
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
14
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 10:37
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Tıklayınız
boxers levels pituitary including controls boxing status healthy functions between common number control higher obtained (237±23 significantly ng/ml) (367±18 considered severe deficient Traumatic professional deficiency Further studies amateur needed clarify dysfunction ©2004 Editrice Kurtis conclu
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