A new lateral thoracic artery perforator flap design with multiple vascular territories in rats

Background To describe a new design for an extended lateral thoracic artery (LTA) perforator flap and investigate its anatomical, dynamic, and potential territories. Materials and methods To assess vascular territories, rats were randomized according to LTA perforator flap type into the surgical groups A, hemidorsal island flap; B, entire dorsal island flap; and C, reduced-size dorsal island flap. Results On postsurgical day 7, the surviving flap areas were 95%, 92%, and 89% in groups A, B, and C, respectively. Necrosis most commonly occurred in the contralateral LTA territories in groups B and C. The immunoreactivities of intercellular adhesion molecule 1 and vascular endothelial growth factor receptor 2 in dynamic territories, as choke vessel markers, were increased. Conclusions We clarified the LTA perforator flap nomenclature and defined its pedicle course and anastomosing patterns; furthermore, we demonstrated that the LTA perforator did not anastomose with its counterpart because of its unidirectional, oblique, and craniocaudal course. The LTA perforator flap was found to be a good model comprising multiple vascular territories and exhibiting continuous necrosis. © 2016 Elsevier Inc.

Yazar Savaş S.A.
Gorgulu T.
Başsorgun C.İ.
Akcal A.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/3977
Tek Biçim Adres 10.1016/j.jss.2016.08.066
Konu Başlıkları Lateral thoracic artery perforator flap
rat
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu
Dergi Adı Journal of Surgical Research
Dergi Cilt Bilgisi 209
Sayfalar 70 - 78
Yayın Yılı 2017
Eser Adı
[dc.title]
A new lateral thoracic artery perforator flap design with multiple vascular territories in rats
Yazar
[dc.contributor.author]
Savaş S.A.
Yazar
[dc.contributor.author]
Gorgulu T.
Yazar
[dc.contributor.author]
Başsorgun C.İ.
Yazar
[dc.contributor.author]
Akcal A.
Yayın Yılı
[dc.date.issued]
2017
Yayıncı
[dc.publisher]
Academic Press Inc.
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Background To describe a new design for an extended lateral thoracic artery (LTA) perforator flap and investigate its anatomical, dynamic, and potential territories. Materials and methods To assess vascular territories, rats were randomized according to LTA perforator flap type into the surgical groups A, hemidorsal island flap; B, entire dorsal island flap; and C, reduced-size dorsal island flap. Results On postsurgical day 7, the surviving flap areas were 95%, 92%, and 89% in groups A, B, and C, respectively. Necrosis most commonly occurred in the contralateral LTA territories in groups B and C. The immunoreactivities of intercellular adhesion molecule 1 and vascular endothelial growth factor receptor 2 in dynamic territories, as choke vessel markers, were increased. Conclusions We clarified the LTA perforator flap nomenclature and defined its pedicle course and anastomosing patterns; furthermore, we demonstrated that the LTA perforator did not anastomose with its counterpart because of its unidirectional, oblique, and craniocaudal course. The LTA perforator flap was found to be a good model comprising multiple vascular territories and exhibiting continuous necrosis. © 2016 Elsevier Inc.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Lateral thoracic artery perforator flap
Konu Başlıkları
[dc.subject]
rat
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0022-4804
İlk Sayfa Sayısı
[dc.identifier.startpage]
70
Son Sayfa Sayısı
[dc.identifier.endpage]
78
Dergi Adı
[dc.relation.journal]
Journal of Surgical Research
Dergi Cilt Bilgisi
[dc.identifier.volume]
209
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.1016/j.jss.2016.08.066
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/3977
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
15
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 11:38
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Tıklayınız
territories perforator vascular groups island dorsal dynamic course demonstrated patterns furthermore anastomosing Background pedicle defined nomenclature clarified Conclusions increased markers vessel receptor anastomose Elsevier necrosis continuous exhibiting multiple comprising craniocaudal oblique unidirectional because counterpart growth
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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