Assessment of tumor markers in patients with chronic renal failure

In this study; serum levels of different tumor markers such as alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), cancer antigen 125 (CA 125), cancer antigen 19-9 (CA 19-9), cancer antigen 15-3 (CA 15-3), and prostatespecific antigen (PSA) in 36 predialysis, 42 hemodialysis (HD), 42 continuous ambulatory peritoneal dialysis (CAPD) patients and 32 healthy volunteers as control group who did not present any clinical symptoms or signs of neoplasia with negative hepatitis markers were studied. The mean serum levels of CEA and CA 19-9 were found to be higher than the control group in predialysis, HD and CAPD patients. Serum levels of CA 125 in CAPD group was found to be higher as compared to the other groups. Serum AFP, CA 15-3 and PSA levels were similar in all groups. In conclusion, serum tumor markers do not have any diagnostic utility and may be unreliable for monitoring malignancies in uremic patients.

Dergi Adı Turkish Journal of Cancer
Dergi Cilt Bilgisi 37
Dergi Sayısı 4
Sayfalar 143 - 147
Yayın Yılı 2007
Eser Adı
[dc.title]
Assessment of tumor markers in patients with chronic renal failure
Yazar
[dc.contributor.author]
Engin H.
Yazar
[dc.contributor.author]
Borazan A.
Yazar
[dc.contributor.author]
Aydemir S.
Yazar
[dc.contributor.author]
Yilmaz A.
Yayın Yılı
[dc.date.issued]
2007
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
In this study; serum levels of different tumor markers such as alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), cancer antigen 125 (CA 125), cancer antigen 19-9 (CA 19-9), cancer antigen 15-3 (CA 15-3), and prostatespecific antigen (PSA) in 36 predialysis, 42 hemodialysis (HD), 42 continuous ambulatory peritoneal dialysis (CAPD) patients and 32 healthy volunteers as control group who did not present any clinical symptoms or signs of neoplasia with negative hepatitis markers were studied. The mean serum levels of CEA and CA 19-9 were found to be higher than the control group in predialysis, HD and CAPD patients. Serum levels of CA 125 in CAPD group was found to be higher as compared to the other groups. Serum AFP, CA 15-3 and PSA levels were similar in all groups. In conclusion, serum tumor markers do not have any diagnostic utility and may be unreliable for monitoring malignancies in uremic patients.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Chronic renal failure
Konu Başlıkları
[dc.subject]
Continuous ambulatory peritoneal dialysis
Konu Başlıkları
[dc.subject]
Hemodialysis
Konu Başlıkları
[dc.subject]
Predialysis
Konu Başlıkları
[dc.subject]
Tumor marker
Haklar
[dc.rights]
info:eu-repo/semantics/closedAccess
ISSN
[dc.identifier.issn]
1019-3103
İlk Sayfa Sayısı
[dc.identifier.startpage]
143
Son Sayfa Sayısı
[dc.identifier.endpage]
147
Dergi Adı
[dc.relation.journal]
Turkish Journal of Cancer
Dergi Sayısı
[dc.identifier.issue]
4
Dergi Cilt Bilgisi
[dc.identifier.volume]
37
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/4405
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
7
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
09 Şubat 2024 06:49
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Tıklayınız
antigen levels markers patients cancer groups higher control predialysis uremic malignancies monitoring unreliable similar utility diagnostic compared conclusion studied hepatitis hemodialysis prostatespecific continuous carcinoembryonic alpha-fetoprotein different ambulatory negative present neoplasia symptoms clinical peritoneal volunteers healthy
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