Can Plateletcrit be a Marker for Recurrent Pregnancy Loss?
Aim: To determine the utility of platelet (PLT) indices for the prediction of recurrent pregnancy loss (RPL). Methods: In all, 208 patients who experienced 2 or more first trimester spontaneous abortions and 95 controls who had no abortions were studied. The hematological markers, including plateletcrit (PCT) and neutrophil (Neu) to lymphocyte (Lym) ratio (NLR), were measured. Thrombophilia genetic tests for factor V Leiden mutation, prothrombin G202I0A mutation, and methylenetetrahydrofolate reductase C677 T and A1298C mutations were performed. Results: The PLT count, PCT, white blood cell count, red cell distribution width (RDW), Lym and Neu count, and NLR were significantly higher in patients with RPL than in controls. The RDW, PLT, and PCT values were higher in the low-risk group, whereas mean PLT volume values were lower than the high-risk group values. Conclusion: Plateletcrit is a low-cost, widely available marker for prediction of RPL in patients with a history of at least 1 abortus. © SAGE Publications.
| Yazar |
Aynloglu O. Islk H. Sahbaz A. Harma M.I. Islk M. Kokturk F. |
| Yayın Türü | Article |
| Tek Biçim Adres | https://hdl.handle.net/20.500.12628/4569 |
| Tek Biçim Adres | 10.1177/1076029614565882 |
| Konu Başlıkları |
clinical thrombophilia
hemostasis recurrent abortion |
| Koleksiyonlar |
Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD Scopus İndeksli Yayınlar Koleksiyonu WoS İndeksli Yayınlar Koleksiyonu |
| Dergi Adı | Clinical and Applied Thrombosis/Hemostasis |
| Dergi Cilt Bilgisi | 22 |
| Dergi Sayısı | 5 |
| Sayfalar | 447 - 452 |
| Yayın Yılı | 2014 |
| Eser Adı [dc.title] | Can Plateletcrit be a Marker for Recurrent Pregnancy Loss? |
| Yazar [dc.contributor.author] | Aynloglu O. |
| Yazar [dc.contributor.author] | Islk H. |
| Yazar [dc.contributor.author] | Sahbaz A. |
| Yazar [dc.contributor.author] | Harma M.I. |
| Yazar [dc.contributor.author] | Islk M. |
| Yazar [dc.contributor.author] | Kokturk F. |
| Yayın Yılı [dc.date.issued] | 2014 |
| Yayıncı [dc.publisher] | SAGE Publications Inc. |
| Yayın Türü [dc.type] | article |
| Özet [dc.description.abstract] | Aim: To determine the utility of platelet (PLT) indices for the prediction of recurrent pregnancy loss (RPL). Methods: In all, 208 patients who experienced 2 or more first trimester spontaneous abortions and 95 controls who had no abortions were studied. The hematological markers, including plateletcrit (PCT) and neutrophil (Neu) to lymphocyte (Lym) ratio (NLR), were measured. Thrombophilia genetic tests for factor V Leiden mutation, prothrombin G202I0A mutation, and methylenetetrahydrofolate reductase C677 T and A1298C mutations were performed. Results: The PLT count, PCT, white blood cell count, red cell distribution width (RDW), Lym and Neu count, and NLR were significantly higher in patients with RPL than in controls. The RDW, PLT, and PCT values were higher in the low-risk group, whereas mean PLT volume values were lower than the high-risk group values. Conclusion: Plateletcrit is a low-cost, widely available marker for prediction of RPL in patients with a history of at least 1 abortus. © SAGE Publications. |
| Kayıt Giriş Tarihi [dc.date.accessioned] | 2019-12-23 |
| Açık Erişim Tarihi [dc.date.available] | 2019-12-23 |
| Yayın Dili [dc.language.iso] | eng |
| Konu Başlıkları [dc.subject] | clinical thrombophilia |
| Konu Başlıkları [dc.subject] | hemostasis |
| Konu Başlıkları [dc.subject] | recurrent abortion |
| Haklar [dc.rights] | info:eu-repo/semantics/openAccess |
| ISSN [dc.identifier.issn] | 1076-0296 |
| İlk Sayfa Sayısı [dc.identifier.startpage] | 447 |
| Son Sayfa Sayısı [dc.identifier.endpage] | 452 |
| Dergi Adı [dc.relation.journal] | Clinical and Applied Thrombosis/Hemostasis |
| Dergi Sayısı [dc.identifier.issue] | 5 |
| Dergi Cilt Bilgisi [dc.identifier.volume] | 22 |
| Tek Biçim Adres [dc.identifier.uri] | https://dx.doi.org/10.1177/1076029614565882 |
| Tek Biçim Adres [dc.identifier.uri] | https://hdl.handle.net/20.500.12628/4569 |
