Peripapillary retinal nerve fiber layer and choroidal thickness in cirrhosis patients

Purpose: To evaluate the effect of cirrhosis on peripapillary retinal nerve fiber layer and choroidal thickness with enhanced depth imaging optical coherence tomography. Methods: This cross sectional, single center study was undertaken at Bulent Ecevit University Ophthalmology department with the participation of internal medicine, Gastroenterology department. Patients who were treated with the diagnosis of cirrhosis (n=75) were examined in the ophthalmology clinic. Age and sex matched patients (n=50) who were healthy and met the inclusion, exclusion criteria were included in the study. Complete ophthalmological examination included visual acuity with Snellen chart, intraocular pressure measurement with applanation tonometry, biomicroscopy of anterior and posterior segments, gonioscopy, axial length measurement, visual field examination, peripapillary retinal nerve fiber layer, central macular and subfoveal choroidal thickness measurements. Results: The difference between intraocular pressure values was not statistically significant between cirrhosis and control group (p=0.843). However, mean peripapillary retinal nerve fiber layer thickness was significantly thinner in cirrhosis group in all regions (p<0.001) and subfoveal choroidal thickness was significantly thinner in cirrhosis group also (p<0.001). Moreover, central macular thickness of cirrhosis group was significantly thicker than the control group (p=0.001). Conclusion: Peripapillary retinal nerve fiber layer and subfoveal choroidal thickness was significantly thinner in cirrhosis patients.

Yazar Akdemir M.O.
Ayar O.
Yazgan S.
Ilikhan S.U.
Celik E.
Ugurbas S.H.
Ustundag Y.
Yayın Türü Article
Tek Biçim Adres https://hdl.handle.net/20.500.12628/6980
Tek Biçim Adres 10.5935/0034-7280.20150072
Konu Başlıkları Cirrhosis
OCT
Peripapillary retinal nerve fiber layer
Subfoveal choroidal thickness
Koleksiyonlar Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed | SOBİAD
Scopus İndeksli Yayınlar Koleksiyonu
Dergi Adı Revista Brasileira de Oftalmologia
Dergi Cilt Bilgisi 74
Dergi Sayısı 6
Sayfalar 345 - 349
Yayın Yılı 2015
Eser Adı
[dc.title]
Peripapillary retinal nerve fiber layer and choroidal thickness in cirrhosis patients
Yazar
[dc.contributor.author]
Akdemir M.O.
Yazar
[dc.contributor.author]
Ayar O.
Yazar
[dc.contributor.author]
Yazgan S.
Yazar
[dc.contributor.author]
Ilikhan S.U.
Yazar
[dc.contributor.author]
Celik E.
Yazar
[dc.contributor.author]
Ugurbas S.H.
Yazar
[dc.contributor.author]
Ustundag Y.
Yayın Yılı
[dc.date.issued]
2015
Yayıncı
[dc.publisher]
Sociedade Brasileira de Oftalmologia
Yayın Türü
[dc.type]
article
Özet
[dc.description.abstract]
Purpose: To evaluate the effect of cirrhosis on peripapillary retinal nerve fiber layer and choroidal thickness with enhanced depth imaging optical coherence tomography. Methods: This cross sectional, single center study was undertaken at Bulent Ecevit University Ophthalmology department with the participation of internal medicine, Gastroenterology department. Patients who were treated with the diagnosis of cirrhosis (n=75) were examined in the ophthalmology clinic. Age and sex matched patients (n=50) who were healthy and met the inclusion, exclusion criteria were included in the study. Complete ophthalmological examination included visual acuity with Snellen chart, intraocular pressure measurement with applanation tonometry, biomicroscopy of anterior and posterior segments, gonioscopy, axial length measurement, visual field examination, peripapillary retinal nerve fiber layer, central macular and subfoveal choroidal thickness measurements. Results: The difference between intraocular pressure values was not statistically significant between cirrhosis and control group (p=0.843). However, mean peripapillary retinal nerve fiber layer thickness was significantly thinner in cirrhosis group in all regions (p<0.001) and subfoveal choroidal thickness was significantly thinner in cirrhosis group also (p<0.001). Moreover, central macular thickness of cirrhosis group was significantly thicker than the control group (p=0.001). Conclusion: Peripapillary retinal nerve fiber layer and subfoveal choroidal thickness was significantly thinner in cirrhosis patients.
Kayıt Giriş Tarihi
[dc.date.accessioned]
2019-12-23
Açık Erişim Tarihi
[dc.date.available]
2019-12-23
Yayın Dili
[dc.language.iso]
eng
Konu Başlıkları
[dc.subject]
Cirrhosis
Konu Başlıkları
[dc.subject]
OCT
Konu Başlıkları
[dc.subject]
Peripapillary retinal nerve fiber layer
Konu Başlıkları
[dc.subject]
Subfoveal choroidal thickness
Haklar
[dc.rights]
info:eu-repo/semantics/openAccess
ISSN
[dc.identifier.issn]
0034-7280
İlk Sayfa Sayısı
[dc.identifier.startpage]
345
Son Sayfa Sayısı
[dc.identifier.endpage]
349
Dergi Adı
[dc.relation.journal]
Revista Brasileira de Oftalmologia
Dergi Sayısı
[dc.identifier.issue]
6
Dergi Cilt Bilgisi
[dc.identifier.volume]
74
Tek Biçim Adres
[dc.identifier.uri]
https://dx.doi.org/10.5935/0034-7280.20150072
Tek Biçim Adres
[dc.identifier.uri]
https://hdl.handle.net/20.500.12628/6980
Görüntülenme Sayısı ( Şehir )
Görüntülenme Sayısı ( Ülke )
Görüntülenme Sayısı ( Zaman Dağılımı )
Görüntülenme
11
09.12.2022 tarihinden bu yana
İndirme
1
09.12.2022 tarihinden bu yana
Son Erişim Tarihi
15 Şubat 2024 17:05
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Tıklayınız
cirrhosis thickness significantly choroidal retinal peripapillary thinner subfoveal between department control central visual patients measurement macular examination intraocular pressure included length applanation anterior gonioscopy segments posterior tonometry biomicroscopy Purpose measurements Peripapillary Conclusion thicker Moreover regions
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